Abstract: The invention relates to a method comprising the following steps: a) use of a support which has at least two different microparticle populations immobilized thereon; b) measuring the fluorescence of the support from step a) with an optical resolution 1, said resolution 1 permitting differentiation of microparticle singlets, doublets, triplets, multiplets and monolayers and determination of the localized position of individual immobilized microparticles; c) contacting the support from step a) with the sample to be analyzed; d) performing at least one additional measurement of the fluorescence of the support during or after contacting in accordance with step c) with a resolution 2; e) assigning the fluorescence values measured with resolution 2 to the individual microparticle singlets, doublets, triplets, multiplets and monolayers locally identified on the support in accordance with step b) and assigned to a particular acceptor molecule population; f) determining the change in fluorescence.

Abstract: The invention relates to an apparatus (100) for detecting analytes (26) in a sample comprising—a base carrier (10); —a multitude of sensor carriers (18) which are arranged on the base carrier (10) and can be assigned to at least two different sensor carrier populations (181, 182, 183); —the sensor carrier populations (181, 182, 183) being defined at least by different sensor molecules (24) which are assigned to the sensor carrier (18) and each have at least one measurable specificity for an analyte (26) or an analyte group, such that the population (181, 182, 183) of the sensor carriers (18) constitutes a coding which enables the assignment of sensor molecules (24) and/or analyte (26).

Abstract: The invention relates to a method and test kit for the detection of analytes in a biological sample, wherein at least one microparticle population is labelled with fluorescent dyes serving as coding fluorescent dyes and reference fluorescent dyes and immobilized, acceptor molecules interacting with labelled analytes being bound to the microparticle population, so that the difference between the fluorescence of the microparticles and analyte(s) can be used to determine which kind of analyte, optionally in which amount, is present in the sample. In particular, the invention finds use in medical diagnostics.

Abstract: The invention suggests a method of producing an array for the detection of components from a biological sample, wherein the detection molecules are immobilized on one or more supports, said support(s) is/are embedded and subjected to curing, the support is separated into sections, and the sections are applied on another support.

Abstract: The invention suggests a method of producing an array for the detection of components from a biological sample, wherein the detection molecules are immobilized on one or more supports, said support(s) is/are embedded and subjected to curing, the support is separated into sections, and the sections are applied on another support.

Abstract: The invention relates to a method and test kit for the detection of analytes in a biological sample, wherein at least one microparticle population is labelled with fluorescent dyes serving as coding fluorescent dyes and reference fluorescent dyes and immobilized, acceptor molecules interacting with labelled analytes being bound to the microparticle population, so that the difference between the fluorescence of the microparticles and analyte(s) can be used to determine which kind of analyte, optionally in which amount, is present in the sample. In particular, the invention finds use in medical diagnostics.

Abstract: A buckle folding machine is provided with a device with which the folding rollers (W1 through W5) can be automatically set to different folding gap widths as a function of the measured or calculated thickness of a sheet of paper or stack passing through the folding gap (F1 through F4). The folding rollers to be adjusted are mounted on pivoted levers (22), which are mounted coaxially in pairs and which be pivoted against permanent restoring forces under the effect of electrically controllable adjusting members (S1 through S5). The adjusting members are actuated by an electronic process computer, which calculates the folding gap widths to be set in the particular case according to a preset working program from measured and/or manually entered paper thicknesses or stack thicknesses and/or fold types. The adjusting members (S1 through S5) comprise a plurality of pneumatic working cylinders, which are arranged in a row in a cascade-like pattern, and whose working strokes mutually add up.

Abstract: Buckle folding machine including folding pockets, which have a paper stop each. One folding pocket being for collection and subsequent joint folding of a plurality of sheets. From the folding pocket the collected sheets of paper pass together through a folding mechanism, having a draw-in point formed by upper and lower draw-in rollers and having at least one pair of folding rollers forming a folding point. A sheet feeder with a conveyor track directed toward the draw-in point, in which a stacking ramp is located, is arranged in front of the draw-in point.

Abstract: A motion indicating device used especially to monitor the movement of sheets of paper, which are moved via conveyor paths. A scanning device has a rotatably mounted scanning member, which lies on the scannable surfaces of the moving sheet of paper and is set into rotation by same, and which is provided with signal elements, which generate motion signals in a stationary electronic signal transmitter by their rotary movements. The scanning member is a ball (8) with uneven weight distribution or a hollow ball (81, 82). The ball is guided freely rotatably in a guide cage (7) and has at least one signal element. A signal transmitter is arranged on a side located diametrically opposite the contact point (19) of the ball (8) and is directed in this plane of rotation toward the ball (8).

Abstract: A buckling-type paper sheet folder comprises a protective housing (7) and two pairs of folding cylinders (W1, W2, W3, W4) which are mounted in a cylinder frame (1) and conjointly driven by an electric motor (4). Folding pockets (5,6) and the cylinder frame are enclosed on all sides by the housing which has two parts, namely a base (8) and a cover (9), that are hinged and/or detachably connected to each other. In the base, a box-like compartment (12) is formed below the folding pockets accommodating the cylinder frame. The cover comprises a wall (45) extending between vertical side walls (40,41) and covering the upper foldin pocket (5) and having a portion (48) forming the upper boundary of a sheet intake opening. The cover further comprises a second wall (54) extending above the second folding pocket (6) inwardly, to form the lower boundary of the intake opening (51), and having a front portion 39.

Abstract: A buckle folding machine with at last one pair of folding rollers and at least one folding pocket (1). The folding pocket includes a top rail (43), which extends over the width of the folding pocket (1) and is attached to lateral toothed belts (26, 27) and has, on its side facing the folding pocket mouth (9), a plurality of stop fingers (44). The stop fingers have front end faces (48), located in a common plane, serve together as a paper stop within the folding pocket (1), and which can be brought by the toothed belts (26, 27) into a front deflecting position, in which their front end faces (48) together act as a paper deflector and guide the material arriving at the folding pocket mouth (9) for folding past the folding pocket (1) and into the next folding station (F2).

Abstract: A paper-folding machine with a plurality of folding rollers, which form a folding station in pairs and the distances between whose axes can be set to different folding gap widths corresponding to the paper thickness to be processed and the number of layers of paper passing through the individual folding stations, as well as with mechanical or electronic feed limiters, which are arranged in front of the individual folding stations and can be set individually to different feed lengths. The thickness of the incoming material to be folded, which is determined by means of a thickness-measuring device (40), and the sheet length of the arriving material to be folded, which is determined by a length-measuring device (41), as well as the desired type of folding and/or the set feed lengths of the individual feed limiters (T1-T4), are entered into a process computer (20) to determine the folding gap widths of the individual pairs of folding rollers (W1-W5).

Abstract: An setup folding machine with at least two folding stations (F1, F2), which are formed by a pair of folding rollers (W1/W2; W2/W3) each. An intake device is provided including two feed rollers (T1, T2), which determines the speed of feed of the material to be folded, the intake device is located in a feed web (4) moving past the first folding station (F1). A enclosure feed mechanism is positioned directed toward the first folding station (F1), arranged behind the intake device. In order for an enclosure to be able to be optionally inserted into the first or second fold, the first folding station (F1) is associated with a knife-like deflecting member (6), which can be moved to the first folding station (F1) while the material is being deflected at the same time to form a fold, and can be actuated individually for each folding process by an electronic control device (21).

Abstract: The paper folding machine is provided with a roller pair (T1,T2) which forms an intake zone (E) and determines the velocity of feed of the material to be folded, and with at least one pair of folding rollers (W1,W2,W3), which forms a folding zone (F1) and is parallel to the former pair of rollers. A stopless feed limiting device, which determines the actual folding length and can be actuated individually for each folding operation by a microprocessor and/or an electronic control circuit as a function of a feed measuring unit, is arranged in a material feed path (4) which extends past the folding zone (F1,F2).

Abstract: A device for folding successively fed sheets which have a plurality of transversely spaced dried adhesive areas thereon includes a plurality of folding rolls arranged in a sheet feedback between which the sheets are fed and which have at least one pocket into which the sheets are fed after they have been folded at least once as they are passed between folding rolls. The sheet wetting device comprises a plurality of moveable belts which are arranged over the sheets as they are fed through the sheet feed path, they are guided and moved through a path in which they overlie each sheet in succession. Construction includes means for holding at least some of the belts into contact with the sheets as they are moved in order to wet the sheets in selected areas in it includes means for passing the belts into association with a belt wetting device or reservoir so that they wet the dry areas which they contact.

Abstract: Idling/final speed governor for internal combustion engines, having a centrifugal-weight regulator (4) which is used for controlling the idling and final speed and produces, against the force of control springs (8), a regulating force corresponding to the engine speed, having a coupling (9) present between a control rod (3), used for controlling the quantity, and the centrifugal-weight regulator (4), having a governor sleeve (7) which has a drag member and having a link (13) between an intermediate lever (12), belonging to the coupling (9), and the control rod (3), with this link (13) having a slide (26) which can be displaced in the quantity-regulating direction, is loaded by a starting spring (27) in the direction of increasing injection quantity and interacts with a full-load stop (32) which is fixed per se but can be changed as a function of operating parameters, such as, for example, by a supercharge-pressure regulator (33), with this change in the stop position signifying a control-travel change which i

Abstract: A pneumatic diaphragm control element for a fuel injection apparatus for internal combustion engines, in particular for supercharged diesel engines, has a thrust rod that is axially displaceable between two end stop counter to the force of a restoring spring, which thrust rod acts upon a control member of the fuel injection apparatus and is connected to a pressure-actuated diaphragm. One end stop determines the position assumed by the thrust rod when there is no pressure and is embodied as a stop screw for the thrust rod. The second end stop defines the position assumed by the thrust rod with maximal pressure being exerted on the diaphragm, and to this end cooperates with a counterpart stop that is adjustably coupled with the thrust rod.

Abstract: A sheet separator for a sheet feeder comprises a friction cylinder which is rotatable for feeding a sheet from a stack of sheets. A retaining member is mounted for radial movement with respect to the friction cylinder. The retaining member has a friction surface which holds back other sheets in the stack and which forms with the friction cylinder a passage gap which is adjusted to the thickness of a sheet to be fed. A carrier is connected to and supports the retaining member. An adjustment mechanism is provided between the carrier and the retaining member for adjusting the passage gap width. A bracket is mounted for radial movement on the carrier and has a contact surface for engaging the friction cylinder or a sheet held in the passage gap. Signal switch is provided in the bracket and is activated by a checking element which is movably mounted to the bracket and engaged with either the carrier or the retaining member.

Abstract: A centrifugal speed governor, functioning as a minimum-maximum-speed governor, includes an adjusting member which is pivotable for adjusting the supply quantity, and the governor rod of the associated injection pump is adjustable via an intermediate lever by means of the adjusting member and a governor spring which is displaceable counter to the force of associated governor springs. The travel of the governor rod is limited in the direction of an increasing supply quantity by a governor rod stop including a starting spring. With the adjusting member resting on an end stop, the governor rod is pressed away from a basic test position (P) into its full-load position (V), and the differential travel (.DELTA.R) thereby resulting is absorbed by an accumulator in the governor linkage, preferably in the governor sleeve. The deflection stroke (A) of the accumulator is only slightly longer than that required to compensate for the differential travel (.DELTA.R).

Abstract: A buckling-type paper sheet folder comprises at least two pairs of folding cylinders W1 and W2 and two folding pockets F1, F2. The adjustable sheet stops 65,66, embodied by stop rails, of the folding pockets F1, F2 are secured to endless belts 67,68,69 and 70 which are drivable, conjointly two and two, through a manually actuable shaft 79 or 80. Scales of length S1 to S8 are carried on scale bands 48 and 49 which are associated each with one of the folding pockets F1 or F2 and displaceable by, the respective drive shafts 79, 80 in synchronism with the sheet stops 65, 66. The scale bands 48 and 49 are mounted in the housing to be visible through windows which are provided with reference marks. The sheet stops 65 and 66 can be set to the desired position through the closed housing by means of knobs 81 and 82. To facilitate the setting of the sheet stops, a plurality of scales S1 to S8 is provided on each scale band, each associated with a folding manner and sheet size, and made separately noticeable by a light.