Patents by Inventor Werner Mantele

Werner Mantele has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230190145
    Abstract: A method of analyzing a material (12) comprising at least one analyte, said method comprising a material status analyzing procedure (76), in which a present status of the material is analyzed, wherein based on a result of said material status analyzing procedure (76), at least one of a selection of analyte-characteristic-wavelengths used during an analyte measurement procedure (78), an absolute time or a relative time proportion of use of analyte-characteristic-wavelengths during said analyte measurement procedure (78), an individual excitation radiation intensity, or a relative weight given to the wavelengths in the analysis, a selection of analyte-characteristic-wavelengths to be used simultaneously during said analyte measurement procedure (78), and a selection of one or more main frequencies of the modulation of said excitation radiation (18) intensity to be used during said analyte measurement procedure (78) is determined.
    Type: Application
    Filed: May 20, 2021
    Publication date: June 22, 2023
    Inventors: Werner Mäntele, Thorsten Lubinski, Sergius Janik, Michael Kaluza
  • Publication number: 20230190146
    Abstract: An apparatus (10) for analyzing a material (12) comprising at least one analyte, said apparatus comprising a measurement body (16) having a contact surface (14) suitable to be brought in thermal contact or pressure-transmitting contact with said material (12), an excitation radiation source (26) configured for irradiating excitation radiation (18) into the material (12) to be absorbed therein, and a detection device for detecting a physical response of the measurement body to heat or a pressure wave received from said material (12) upon absorption of said excitation radiation (18) and for generating a response signal indicative of the degree of absorption of excitation radiation, wherein a protrusion (80) is provided, said protrusion having a front surface (82) facing said material (12) and being in contact with the material when the material is brought in contact with the contact surface, and wherein said excitation radiation (18) is irradiated into the material (12) through said front surface (82) of said p
    Type: Application
    Filed: May 26, 2021
    Publication date: June 22, 2023
    Inventors: Werner Mäntele, Thorsten Lubinski, Sergius Janik, Michael Kaluza
  • Publication number: 20230181064
    Abstract: Disclosed herein is an apparatus (10) for analyzing a material (12) comprising at least one analyte, said apparatus (10) comprising a measurement body (16) having a contact surface (14) suitable to be brought in thermal contact or pressure-transmitting contact with said material (12), an excitation radiation source configured for irradiating excitation radiation into the material (12) to be absorbed therein, and a detection light source for generating a detection light beam (22) travelling through at least a portion of said measurement body (16) or a component included in said measurement body, wherein said detection light beam is directed to be totally or partially reflected at said contact surface (14), wherein said contact surface (14) of the measurement body is curved in at least one principal direction in the area where the detection light beam (22) is reflected.
    Type: Application
    Filed: July 31, 2020
    Publication date: June 15, 2023
    Inventors: Werner Mäntele, Thorsten Lubinski, Sergius Janik, Michael Kaluza
  • Publication number: 20230181063
    Abstract: A method of analyzing a material (12) comprising at least one analyte, wherein analyte-wavelength-specific measurements are interspersed with reference measurements (80), and wherein response signals obtained for the reference measurements (80) are used for one or more of calibrating an excitation radiation source (26) for generating said excitation radiation, calibrating said detection device, recognizing a variation in the measurement conditions by comparing results of individual reference measurements (80), adapting the analyte measurement procedure (78) with respect to one or more of the entire duration thereof, the absolute or relative duration of analyte-wavelength-specific measurements for a given analyte-characteristic-wavelength, or terminating and/or restarting the analyte measurement procedure, and adapting the analysis carried out in the analyzing step.
    Type: Application
    Filed: May 20, 2021
    Publication date: June 15, 2023
    Inventors: Werner Mäntele, Thorsten Lubinski, Sergius Janik, Michael Kaluza
  • Patent number: 11639894
    Abstract: A method and apparatus for analyzing a substance is disclosed. An optical medium is arranged on a substance surface with at least one region of the optical medium surface in contact with the substance surface. An excitation light beam is emitted through the contacting region of the medium surface (to the substance surface. A measurement light beam is emitted through the optical medium to the contacting region of the medium surface such that the measurement light beam and the excitation light beam overlap on the interface of the optical medium and of the substance surface, on which the measurement light beam is reflected. A deflection of the reflected measurement light beam is detected in dependence on the wavelength of the excitation light beam. The substance is then analyzed based on the detected deflection of the measurement light beam in dependence on the wavelength of the excitation light beam.
    Type: Grant
    Filed: January 4, 2021
    Date of Patent: May 2, 2023
    Assignee: DiaMonTech AG
    Inventors: Werner Mäntele, Miguel Angel Pleitez Rafael, Tobias Lieblein, Otto Hertzberg, Alexander Bauer, Hermann Von Lilienfeld-Toal, Arne Küderle, Tabea Pfuhl
  • Publication number: 20210148817
    Abstract: A method and apparatus for analyzing a substance is disclosed. An optical medium is arranged on a substance surface with at least one region of the optical medium surface in contact with the substance surface. An excitation light beam is emitted through the contacting region of the medium surface (to the substance surface. A measurement light beam is emitted through the optical medium to the contacting region of the medium surface such that the measurement light beam and the excitation light beam overlap on the interface of the optical medium and of the substance surface, on which the measurement light beam is reflected. A deflection of the reflected measurement light beam is detected in dependence on the wavelength of the excitation light beam. The substance is then analyzed based on the detected deflection of the measurement light beam in dependence on the wavelength of the excitation light beam.
    Type: Application
    Filed: January 4, 2021
    Publication date: May 20, 2021
    Inventors: Werner Mäntele, Miguel Angel Pleitez Rafael, Tobias Lieblein, Otto Hertzberg, Alexander Bauer, Hermann Von Lilienfeld-Toal, Arne Küderle, Tabea Pfuhl
  • Patent number: 10953103
    Abstract: The present invention pertains to a composition comprising at least one biocompatible and biodegradable polymer, the polymer further comprising nanocarriers wherein the nanocarriers comprise a drug. Moreover, also encompassed by the invention is the use of the composition in the treatment of a disease and a method for manufacturing the composition.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: March 23, 2021
    Assignee: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V
    Inventors: Matthias Wacker, Susanne Beyer, Michael Parnham, Werner Mäntele, Li Xie, Vitali Vogel
  • Patent number: 10883933
    Abstract: The invention relates to analyzing a substance. An optical medium is arrange on a substance surface with at least one region of the optical medium surface in contact with the substance surface. An excitation light beam is emitted through the contacting region of the medium surface to the substance surface. A measurement light beam is emitted through the optical medium to the contacting region of the medium surface such that the measurement light beam and the excitation light beam overlap on the interface of the optical medium and of the substance surface, on which the measurement light beam is reflected. A deflection of the reflected measurement light beam is detected in dependence on the wavelength of the excitation light beam. The substance is then analyzed based on the detected deflection of the measurement light beam in dependence on the wavelength of the excitation light beam.
    Type: Grant
    Filed: June 16, 2015
    Date of Patent: January 5, 2021
    Assignee: DiaMonTech AG
    Inventors: Werner Mäntele, Miguel Angel Pleitez Rafael, Tobias Lieblein, Otto Hertzberg, Alexander Bauer, Hermann Von Lilienfeld-Toal, Arne Küderle, Tabea Pfuhl
  • Publication number: 20180318433
    Abstract: The present invention pertains to a composition comprising at least one biocompatible and biodegradable polymer, said polymer further comprising nanocarriers wherein said nanocarriers comprise a drug. Moreover, also encompassed by the invention is the use of said composition in the treatment of a disease and a method for manufacturing said composition.
    Type: Application
    Filed: November 4, 2016
    Publication date: November 8, 2018
    Applicant: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.
    Inventors: Matthias WACKER, Susanne BEYER, Michael PARNHAM, Werner MÄNTELE, Li XIE, Vitali VOGEL
  • Publication number: 20170146455
    Abstract: The invention relates to analyzing a substance. An optical medium is arranged on a substance surface with at least one region of the optical medium surface in contact with the substance surface. An excitation light beam is emitted through the contacting region of the medium surface to the substance surface. A measurement light beam is emitted through the optical medium to the contacting region of the medium surface such that the measurement light beam and the excitation light beam overlap on the interface of the optical medium and of the substance surface, on which the measurement light beam is reflected. A deflection of the reflected measurement light beam is detected in dependence on the wavelength of the excitation light beam. The substance is then analyzed based on the detected deflection of the measurement light beam in dependence on the wavelength of the excitation light beam.
    Type: Application
    Filed: June 16, 2015
    Publication date: May 25, 2017
    Inventors: Werner Mäntele, Miguel Angel Pleitez Rafael, Tobias Lieblein, Otto Hertzberg, Alexander Bauer, Hermann Von Lilienfeld-Toal, Arne Küderle, Tabea Pfuhl
  • Patent number: 7920260
    Abstract: A measuring device determines the size, size distribution, and/or concentration of nanoscopic particles or hollow spaces in a measuring sample, the degree of opacity of such measuring samples, or the degree of roughness of surfaces by determining the wavelength and scattering angle dependent intensities of a measuring radiation scattered on a measuring sample. The measuring device comprises a retaining device for a measuring sample to be measured, a detector comprising at least one detector inlet, an evaluation unit, and at least two radiation sources that are respectively at a distance from each other and at a distance from the measuring sample. Via the radiation sources, a ray bundle can in each case be emitted in an essentially parallel beam in the direction of the measuring sample. The ray bundles directed onto the measuring sample are aligned or can be aligned in different angles onto the measuring sample.
    Type: Grant
    Filed: February 2, 2007
    Date of Patent: April 5, 2011
    Assignee: Johann Wolfgang Goethe-Universität
    Inventors: Werner Mäntele, Vitali Vogel, Oliver Klein, Lea Schröder
  • Patent number: 7812312
    Abstract: The invention relates to an infrared measuring device, especially for the spectrometry of aqueous systems. Said device comprises at least one measuring unit, especially a measuring cell, also comprising at least one ATR-body and at least one infrared light source. The measuring unit contains at least one ATR-body which comprises at least two planar, substantially parallel limiting surfaces and which is transparent with respect to measuring radiation and which has an index of refraction which is greater than that of the medium which is arranged next to at least one limiting surface and which is to be examined, especially larger or equal to 1.5. The IR-measuring radiation on at least one of the planar, parallel limiting surfaces of the ATR-body can be totally reflected in an attenuated manner by at least six times.
    Type: Grant
    Filed: April 3, 2003
    Date of Patent: October 12, 2010
    Assignee: Johann Wolfgang Goethe-Universitaet
    Inventors: Werner Mäntele, Oliver Klein, Christian Zscherp, Andreas Barth, Hermann Von Lillienfeld-Toal, Hellmuth Von Prollius, Frithjof von Germar, Heribert Offermanns
  • Publication number: 20090185160
    Abstract: The present invention relates to a measuring device to determine the size, size distribution and/or concentration of nanoscopic particles or hollow spaces in a measuring sample, the degree of opacity of such measuring samples, or the degree of roughness of surfaces by determining the wavelength and scattering angle dependent intensities of a measuring radiation scattered on a measuring sample, comprising a retaining device for a measuring sample to be measured, a detector, comprising at least one detector inlet, an evaluation unit and at least two radiation sources, which are respectively at a distance from each other and at a distance from the measuring sample, which comprise a multiple wavelength spectrum or a continuous spectrum, and the radiation intensities of which are adjustable and/or determinable, wherein via the radiation sources one ray bundle can in each case be emitted in an essentially parallel beam in the direction of a measuring sample, and wherein the ray bundles which can be directed onto th
    Type: Application
    Filed: February 2, 2007
    Publication date: July 23, 2009
    Applicant: JOHANN WOLFGANG GOETHE-UNIVERSITAT
    Inventors: Werner Mäntele, Vitali Vogel, Oliver Klein, Lea Schröder
  • Publication number: 20060043301
    Abstract: The invention relates to an infrared measuring device, especially for the spectrometry of aqueous systems. Said device comprises at least one measuring unit, especially a measuring cell, also comprising at least one ATR-body and at least one infrared light source. The measuring unit contains at least one ATR-body which comprises at least two planar, substantially parallel limiting surfaces and which is transparent with respect to measuring radiation and which has an index of refraction which is greater than that of the medium which is arranged next to at least one limiting surface and which is to be examined, especially larger or equal to 1.5. The IR-measuring radiation on at least one of the planar, parallel limiting surfaces of the ATR-body can be totally reflected in an attenuated manner by at least six times.
    Type: Application
    Filed: April 3, 2003
    Publication date: March 2, 2006
    Inventors: Werner Mantele, Oliver Klein, Christian Zscherp, Andreas Barth, Hermann Lillienfeld-Toal, Hellmuth Prollius, Frithjof Germar, Heribert Offermanns