Abstract: Compounds of general formula I as well as pharmaceutically acceptable salts and esters thereof, are potent inhibitors of neuropeptide Y and can be used in the form of pharmaceutical preparations for the treatment or prevention of various disease states and related morbidities including obesity.

Abstract: Compounds of formula I 1

Abstract: What is described here is a method of manufacturing progressive ophthalmic lenses whereof each is produced in correspondence with the individual data of a specific spectacle wearer, and whereof each presents a first surface having a defined surface power value in the surface apex, and presents a non-spherical second surface (prescription surface) whose surface power varies along a line (referred to as principal line in the following) that follows at least approximately the main line of sight when the view is lowered, such that the ophthalmic lens produces a first effect in a first reference point, which is suitable for viewing in a first distance envisaged for the respective application, and that this effect varies along the principal line by a predetermined value (addition Add) to a second value present in a second reference point, which is suitable for viewing in a second distance envisaged for the respective application, and whose second surface possibly presents a surface astigmatism optionally for pa

Abstract: A spectacle lens is provided with a region (distance portion) designed for viewing at greater distances and, in particular, “to infinity”, a region (near portion) designed for viewing at short distances and, in particular, “reading distances”, and a progression zone disposed between the distance portion and the near portion, in which the power of the spectacle lens increases from the value in the distance reference point located in the distance portion to the value at the near reference point located in the near portion along a line (principal meridian) curving towards the nose. The invention is marked by specific conditions for the astigmatic deviation and/or the mean “as worn” power being observed.

Abstract: Described is a spectacle lens comprising a region (distance portion) designed for viewing at large distances and in particular “to infinity”, a region (near portion) designed for viewing at short distances and in particular “reading distances”, and a progressive zone disposed between the distance portion and the near portion, in which the power of the spectacle lens increases from a value at a distance reference point located in the distance portion to a value at the near reference point located in the near portion along a curve (principal line) veering towards the nose. The invention is distinct in that the astigmatic deviation, i.e.

Abstract: What is described here is a method of manufacturing spectacles comprising individual progressive ophthalmic lenses, including the following steps: selection of a spectacle frame, detection of the shape of the lens rings with a precision better than ±0.

Abstract: Described is a spectacle lens comprising a region (distance portion) designed for viewing at large distances and in particular “to infinity”, a region (near portion) designed for viewing at short distances and in particular “reading distances”, and a progressive zone disposed between the distance portion and the near portion, in which the power of the spectacle lens increases from a value at a distance reference point located in the distance portion to a value at the near reference point located in the near portion along a curve (principal line) veering towards the nose. The invention is distinct in that the astigmatic deviation, i.e.

Abstract: Compounds of formula I 1

Abstract: Compounds of general formula I 1

Abstract: The invention relates to an efficient and interference insensitive authentication test procedure for accessing a machine control (1). Said procedure is carried out through reading and checking of cards (10-12) in a centralised control system and/or in decentralised control systems.

Abstract: A tissue holder (1, 1a) has a first connector (2, 2a) which can be connected to a tissue part and a second connector (3, 3a) which can be connected to a further tissue part. The tissue holder further holds the two connectors (2, 2a; 3, 3a) and thus the tissue parts relative to one another. The first and second connectors (2, 2a; 3, 3a) each have at least one curved spike (21, 22, 21a, 22a; 31, 32, 31a, 32a) which extends around the longitudinal axis of the tissue holder (1, 1a).

Abstract: What is described here is a method of manufacturing progressive ophthalmic lenses whereof each is produced in correspondence with the individual data of a specific spectacle wearer, and whereof each

Abstract: An optical system, in particular a microlithographic projection printing installation, has in particular a slot-shaped image field or rotationally non-symmetrical illumination. The system comprises a light source (30) as well as at least one optical element, in particular a lens or a mirror. In the region of at least one surface acted upon by the radiation (1) of the light source (30) the optical element is substantially symmetrical in relation to an axis of rotational symmetry (5). The optical element or its housing (6) is rotatably connected to a frame (7) by at least one bearing (8, 9, 10). An actuator (18) sets the optical element (25) or its housing (6) in rotation about the axis of rotational symmetry (5). The actuation cooperates with a control device (23). The latter activates the actuator (18) for rotation of the optical element at least temporarily during the period, when the optical element is exposed to lumination. In such a manner rotationally non-symmetrical image defects are compensated.

Abstract: An optical arrangement, in particular a microlithographic projection printing installation, has in particular a slot-shaped image field or rotationally non-symmetrical illumination. A refractive optical element, e.g. a lens (2), is heated by the rotationally non-symmetrical radiated impingement (3) of a light source. At least one electric heating element is coupled to the optical element. Said heating element comprises a resistance heating coating carried by the optical element. In the region of the surface (3) of the optical element acted upon by the radiation of the light source the resistance heating coating is substantially optically transparent. It comprises a plurality of parallel, electrically mutually insulated coating strips (5 to 10). A heating current source (17 to 19) is additionally part of the heating element.

Abstract: Quinoline derivatives are useful as neuropeptide Y (NPY) receptor ligands and are particularly effective as neuropeptide Y (NPY) antagonists. These compounds are useful in pharmaceutical preparations for the treatment or prevention of arthritis, cardiovascular diseases, diabetes, renal failure, eating disorders, or obesity.

Abstract: A gas generator for a vehicle occupant restraint system. The gas generator comprises a housing, a filter chamber, and a combustion chamber which is filled with solid propellant and which has an outflow end. The gas generator further comprises at least one igniter unit which has an igniter and ignites the solid propellant, and comprises at least one filter which adjoins the solid propellant at the outflow end and delimits the combustion chamber. The filter has a central part which at least in sections has the shape of a cone and tapers in a direction towards an interior of the combustion chamber. The solid propellant laterally adjoins the conical section.

Abstract: An optical arrangement, in particular a projection exposure system for microlithography, has, in particular, a slit-shaped image field or a non-rotational-symmetric illumination. As a result, an optical element (101) is exposed in a non-rotational-symmetric manner to the radiation of the light source (110, 111, 112). The optical element (101) has an absorbing coating (104, 105). The absorption of the coating (104, 105) is distributed in such a manner that it is non-rotation-symmetrical in a manner that is at least approximately complementary to the intensity distribution of the exposure to the radiation (107, 108, 109) of the light source (110, 111, 112). As a result of the energy absorbed in the coating (104, 105), an additional heating of the optical element (101) takes place that results in a better non-rotational-symmetric temperature distribution and, consequently, a compensation for light-induced imaging errors.

Abstract: A multi-stage gas generator comprises a housing with an outer wall and also inner walls, at least two combustion chambers filled with at least one propellant charge, one igniter each associated with a propellant charge for the independent activation of each propellant charge, and at least one thermal insulation arrangement between the propellant charges. The arrangement reduces a transport of thermal energy, generated on the ignition of a propellant charge, to the other non-ignited propellant charge to such a high extent that the non-ignited propellant charge remains below its autogenous ignition temperature. Instead of or additionally to the thermal arrangement a cooling arrangement may be provided.

Abstract: An assay for compounds useful in the treatment of a bacterial induced coagulation disorder has the following steps: a) incubating a plasma sample with a strain of bacteria; b) adding a compound to be assayed to the plasma sample before, during or after step (a); c) conducting an activated partial thromboplastin time test; d) determining the clotting time.

Abstract: Kinin antagonists, especially bradykinin antagonists, can be used for treating bacterial infections, in particular infections caused by bacteria belonging to the genera Streptococcus, Escherichia, Salmonella, Staphylococcus, Klebsiella, Moracella, Haemophilus and Yersinia.