Patents by Inventor Werner Sarlikiotis

Werner Sarlikiotis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Injection solution of an LHRH antagonist
    Patent number: 7790686
    Abstract: An aqueous injectable solution of an LHRH antagonist, such as Cetrorelix, in an organic, pharmaceutically acceptable acid, such as gluconic acid.
    Type: Grant
    Filed: February 27, 2007
    Date of Patent: September 7, 2010
    Inventors: Werner Sarlikiotis, Horst Bauer, Matthias Rischer, Jürgen Engel, Frank Güthlein, Dominique Di Stefano
  • Pharmaceutical administration form for peptides, process for its preparation, and use
    Patent number: 7718599
    Abstract: The invention relates to pharmaceutical compositions suitable for parenteral administration comprising, peptides in the form of acetate, gluconate, glucuronate, lactate, citrate, ascorbate, benzoate or phosphate salts in dissolved or dispersed form and at least one of the acids for forming the salts in free acid form.
    Type: Grant
    Filed: May 18, 2001
    Date of Patent: May 18, 2010
    Assignee: AEterna Zentaris GmbH
    Inventors: Horst Bauer, Michael Damm, Werner Sarlikiotis
  • Pharmaceutical administration form for peptides, process for its preparation, and use
    Patent number: 7696149
    Abstract: A method for preventing aggregation of an LHRH antagonist in a pharmaceutical composition. The method comprises combining the LHRH antagonist in the form of an acetate, gluconate, glucuronate, lactate, citrate, ascorbate, benzoate or phosphate salt and at least one of the acids for forming the salts in free acid form.
    Type: Grant
    Filed: January 4, 2005
    Date of Patent: April 13, 2010
    Assignee: AEterna Zentaris GmbH
    Inventors: Horst Bauer, Michael Damm, Werner Sarlikiotis
  • Solid peptide preparations for inhalation and their preparation
    Publication number: 20090142407
    Abstract: The invention relates to solid pharmaceutical preparations, in particular for inhalatory administration in mammals, their preparation and their use such as, for example, in powder inhalers.
    Type: Application
    Filed: June 4, 2008
    Publication date: June 4, 2009
    Applicant: MEDA Pharama GmbH & Co. KG
    Inventors: Rosario Lizio, Michael Damm, Werner Sarlikiotis, Elisabeth Wolf-Heuss
  • Injection solution of an LHRH antagonist
    Publication number: 20070161571
    Abstract: An aqueous injectable solution of an LHRH antagonist, such as Cetrorelix, in an organic, pharmaceutically acceptable acid, such as gluconic acid.
    Type: Application
    Filed: February 27, 2007
    Publication date: July 12, 2007
    Inventors: Werner Sarlikiotis, Horst Bauer, Matthias Rischer, Jurgen Engel, Frank Guthlein, Dominique Di Stefano
  • Injectable solution of an LHRH antagonist
    Patent number: 7214662
    Abstract: An aqueous injectable soution of an LHRH antagonist, such as Cetrorelix, in an organic, pharmaceutically acceptable acid, such as gluconic acid.
    Type: Grant
    Filed: October 23, 2002
    Date of Patent: May 8, 2007
    Assignee: Zentaris GmbH
    Inventors: Werner Sarlikiotis, Horst Bauer, Matthias Rischer, Jürgen Engel, Frank Güthlein, Dominique Di Stefano
  • Pharmaceutical administration form for peptides, process for its preparation, and use
    Publication number: 20050159335
    Abstract: A method for preventing aggregation of an LHRH antagonist in a pharmaceutical composition. The method comprises combining the LHRH antagonist in the form of an acetate, gluconate, glucuronate, lactate, citrate, ascorbate, benzoate or phosphate salt at least one of the acids for forming the salts in free acid form.
    Type: Application
    Filed: January 4, 2005
    Publication date: July 21, 2005
    Inventors: Horst Bauer, Michael Damm, Werner Sarlikiotis
  • Solid peptide preparations for inhalation and their preparation
    Publication number: 20050014677
    Abstract: The invention relates to solid pharmaceutical preparations, in particular for inhalatory administration in mammals, their preparation and their use such as, for example, in powder inhalers.
    Type: Application
    Filed: March 23, 2004
    Publication date: January 20, 2005
    Inventors: Rosario Lizio, Michael Damm, Werner Sarlikiotis, Elisabeth Wolf-Heuss
  • Pharmaceutical forms for the oral administration of mesna
    Publication number: 20030119906
    Abstract: The invention relates to pharmaceutical forms for oral administration in the form of tablets, film-coated tablets, pellets or granules comprising at least 88% of mesna, produced by granulation with up to 15% of water, based on the amount of solid employed, and also tablets, film-coated tablets, pellets or granules comprising at least 80% of mesna, produced by direct compression or compaction without the use of organic solvents.
    Type: Application
    Filed: January 3, 2003
    Publication date: June 26, 2003
    Applicant: ASTA Medical AG
    Inventors: Jurgen Rawert, Werner Sarlikiotis
  • Injectable solution of an LHRH antagonist
    Publication number: 20030100509
    Abstract: An aqueous injectable soution of an LHRH antagonist, such as Cetrorelix, in an organic, pharmaceutically acceptable acid, such as gluconic acid.
    Type: Application
    Filed: October 23, 2002
    Publication date: May 29, 2003
    Inventors: Werner Sarlikiotis, Horst Bauer, Matthias Rischer, Jurgen Engel
  • Solid pharmaceutical compositions containing hexedecylphosphocholine (miltefosine) for oral administration in the treatment of leishmaniasis
    Patent number: 6544551
    Abstract: The present invention relates to new solid pharmaceutical compositions containing hexadecylphosphocholine (miltefosine) for oral administration in the treatment of leishmaniasis, a process for the manufacture of said pharmaceutical composition, a dosage scheme for oral administration of said pharmaceutical composition in the treatment of leishmaniasis, and finally a combination comprising said solid pharmaceutical composition, antiemeticum, and/or an antidiarrhoeal.
    Type: Grant
    Filed: July 24, 2000
    Date of Patent: April 8, 2003
    Assignee: Zentaris AG
    Inventors: Juergen Engel, Werner Sarlikiotis, Thomas Klenner, Peter Hilgard, Dieter Sauerbier, Eckhard Milsmann
  • Solid peptide preparations for inhalation and their preparation
    Publication number: 20020122826
    Abstract: The invention relates to solid pharmaceutical preparations, in particular for inhalatory administration in mammals, their preparation and their use such as, for example, in powder inhalers.
    Type: Application
    Filed: August 31, 2001
    Publication date: September 5, 2002
    Inventors: Rosario Lizio, Michael Damm, Werner Sarlikiotis, Elisabeth Wolf-Heuss
  • Pharmaceutical forms for the oral administration of mesna
    Publication number: 20020119194
    Abstract: The invention relates to pharmaceutical forms for oral administration in the form of tablets, film-coated tablets, pellets or granules comprising at least 88% of mesna, produced by granulation with up to 15% of water, based on the amount of solid employed, and also tablets, film-coated tablets, pellets or granules comprising at least 80% of mesna, produced by direct compression or compaction. without the use of organic solvents.
    Type: Application
    Filed: October 19, 2001
    Publication date: August 29, 2002
    Inventors: Jurgen Rawert, Werner Sarlikiotis
  • Pharmaceutical administration form for peptides, process for its preparation, and use
    Publication number: 20020039996
    Abstract: The invention relates to pharmaceutical administration forms suitable for parenteral administration, which contains [sic] peptides prone to aggregation in the form of their acetate, gluconate, glucuronate, lactate, citrate, ascorbate, benzoate or phosphate salts in dissolved or dispersed form and additionally comprises [sic] one of the acids mentioned as free acid.
    Type: Application
    Filed: May 18, 2001
    Publication date: April 4, 2002
    Inventors: Horst Bauer, Michael Damm, Werner Sarlikiotis
  • Dosage forms containing thioctic acid or solid salts of thioctic acid with improved release and bioavailability
    Patent number: 6348490
    Abstract: Novel, advantageous dosage forms of thioctic acid and the enantiomers thereof together with thioctic acid salts are described. The pharmaceutical formulations according to the invention are used for the production of pharmaceutical dosage forms which release the active ingredient more rapidly and have greater bioavailability than previous forms.
    Type: Grant
    Filed: August 20, 1999
    Date of Patent: February 19, 2002
    Assignee: Asta Medica Aktiengesellschaft
    Inventors: Helmut Hettche, Matthias Rischer, Werner Sarlikiotis
  • Pharmaceutical forms for the oral administration of mesna
    Patent number: 6322812
    Abstract: The invention relates to pharmaceutical forms for oral administration in the form of tablets, film-coated tablets, pellets or granules comprising at least 88% of mesna, produced by granulation with up to 15% of water, based on the amount of solid employed, and also tablets, film-coated tablets, pellets or granules comprising at least 80% of mesna, produced by direct compression or compaction, without the use of organic solvents.
    Type: Grant
    Filed: April 27, 1999
    Date of Patent: November 27, 2001
    Assignee: ASTA Medica AG
    Inventors: Jurgen Rawert, Werner Sarlikiotis
  • Particulate formulation for administration by inhalation
    Patent number: 6284287
    Abstract: A pharmaceutical formulation for administration by inhalation, a micronized active compound or micronized active compound mixture with a mean particle size of 0.1 &mgr;m to 10 &mgr;m being applied to a pharmaceutically acceptable excipient having a mean particle size of 200 &mgr;m to 1000 &mgr;m without the use of binders.
    Type: Grant
    Filed: April 2, 1997
    Date of Patent: September 4, 2001
    Assignee: Asta Medica AG
    Inventors: Werner Sarlikiotis, Anne De Boer
  • Dosage forms containing thioctic acid or solid salts of thioctic acid with improved release and bioavailability
    Patent number: 5990152
    Abstract: Novel, advantageous dosage forms of thioctic acid and the enantiomers thereof together with thioctic acid salts are described. The pharmaceutical formulations according to the invention are used for the production of pharmaceutical dosage forms which release the active ingredient more rapidly and have greater bioavailability than previous forms.
    Type: Grant
    Filed: February 12, 1997
    Date of Patent: November 23, 1999
    Assignee: Asta Medica Aktiengesellschaft
    Inventors: Helmut Hettche, Matthias Rischer, Werner Sarlikiotis
  • Tablets with thioctic acid of specific particle size
    Patent number: 5527539
    Abstract: The invention relates to a drug formulation in the form of tablets containing thioctic acid (.alpha.-lipoic acid) with an active ingredient content between 45% by weight and 99.9% by weight. The invention is characterized in that 20% to 100% of the active ingredient used has a particle size exceeding 100 .mu.m, particulary between 100 .mu.m and 710 .mu.m, preferably 30% to 80% a particle size between 200 .mu.m and 710 .mu.m.
    Type: Grant
    Filed: January 5, 1995
    Date of Patent: June 18, 1996
    Assignee: ASTA Medica Aktiengesellschaft
    Inventors: Werner Sarlikiotis, Helmut Hettche