Patents by Inventor Werner Skubalia

Werner Skubalia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microbiological reduction of 15-ketoprostaglandin intermediates
    Patent number: 4247635
    Abstract: A process for the preparation of a 15 .alpha.-hydroxyprostaglandin intermediate of the formula ##STR1## wherein R.sub.1 is phenoxymethyl, phenoxymethyl substituted on the phenyl moiety by halogen or trifluoromethyl, or alkyl of 1-5 carbon atoms, andR.sub.2 is hydrogen, acetyl, benzoyl or p-phenylbenzoyl,which comprises stereospecifically microbiologically reducing a corresponding 15-ketone of the formula ##STR2## with a strain of the microorganism Kloeckera, Saccharomyces or Hansenula.
    Type: Grant
    Filed: December 5, 1979
    Date of Patent: January 27, 1981
    Assignee: Schering Aktiengesellschaft
    Inventors: Klaus Kieslich, Bernd Raduchel, Werner Skubalia, Helmut Vorbruggen, Helmut Dahl