Patents by Inventor Werner Strüver

Werner Strüver has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CROSSLINKED CATION EXCHANGE POLYMERS, COMPOSITIONS AND USE IN TREATING HYPERKALEMIA
    Publication number: 20220000906
    Abstract: The present invention is directed to crosslinked cation exchange polymers comprising a fluoro group and an acid group, pharmaceutical compositions of these polymers, compositions of a linear polyol and a salt of such polymer. Crosslinked cation exchange polymers having beneficial physical properties, including combinations of particle size, particle shape, particle size distribution, viscosity, yield stress, compressibility, surface morphology, and/or swelling ratio are also described. These polymers and compositions are useful to bind potassium in the gastrointestinal tract.
    Type: Application
    Filed: May 18, 2021
    Publication date: January 6, 2022
    Inventors: Paul Mansky, Detlef Albrecht, Michael Burdick, Han-Ting Chang, Dominique Charmot, Eric Connor, Sherin Halfon, I-Zu Huang, Mingjun Liu, Ramakrishnan Chidambaram, Jonathan Mills, Werner Strüver
  • LINEAR POLYOL STABILIZED POLYFLUOROACRYLATE COMPOSITIONS
    Publication number: 20210228620
    Abstract: The present invention is directed to compositions of a linear polyol and a salt of a crosslinked cation exchange polymer comprising a fluoro group and an acid group. These compositions are useful to bind potassium in the gastrointestinal tract.
    Type: Application
    Filed: April 5, 2021
    Publication date: July 29, 2021
    Inventors: Detlef Albrecht, Michael Burdick, Han-Ting Chang, Dominique Charmot, Ramakrishnan Chidambaram, Eric Connor, Sherin Halfon, I-Zu Huang, Mingjun Liu, Jonathan Mills, Werner Strüver
  • CROSSLINKED CATION EXCHANGE POLYMERS, COMPOSITIONS AND USE IN TREATING HYPERKALEMIA
    Publication number: 20200289550
    Abstract: The present invention is directed to crosslinked cation exchange polymers comprising a fluoro group and an acid group, pharmaceutical compositions of these polymers, compositions of a linear polyol and a salt of such polymer. Crosslinked cation exchange polymers having beneficial physical properties, including combinations of particle size, particle shape, particle size distribution, viscosity, yield stress, compressibility, surface morphology, and/or swelling ratio are also described. These polymers and compositions are useful to bind potassium in the gastrointestinal tract.
    Type: Application
    Filed: November 1, 2019
    Publication date: September 17, 2020
    Inventors: Paul Mansky, Detlef Albrecht, Michael Burdick, Han-Ting Chang, Dominique Charmot, Eric Connor, Sherin Halfon, I-Zu Huang, Mingjun Liu, Ramakrishnan Chidambaram, Jonathan Mills, Werner Strüver
  • CROSSLINKED POLYFLUOROACRYLIC ACID AND PROCESSES FOR THE PREPARATION THEREOF
    Publication number: 20200095354
    Abstract: The present invention is directed to crosslinked cation exchange polymers comprising a fluoro group and an acid group and being a polymerization product of at least three monomers. Pharmaceutical compositions of these polymers are useful to bind potassium in the gastrointestinal tract.
    Type: Application
    Filed: November 25, 2019
    Publication date: March 26, 2020
    Inventors: Han-Ting Chang, Dominique Charmot, Mingjun Liu, Werner Strüver
  • LINEAR POLYOL STABILIZED POLYFLUOROACRYLATE COMPOSITIONS
    Publication number: 20180125881
    Abstract: The present invention is directed to compositions of a linear polyol and a salt of a crosslinked cation exchange polymer comprising a fluoro group and an acid group. These compositions are useful to bind potassium in the gastrointestinal tract.
    Type: Application
    Filed: January 9, 2018
    Publication date: May 10, 2018
    Inventors: Detlef Albrecht, Michael Burdick, Han-Ting Chang, Dominique Charmot, Ramakrishnan Chidambaram, Eric Connor, Sherin Halfon, I-Zu Huang, Mingjun Liu, Jonathan Mills, Werner Strüver
  • CROSSLINKED POLYFLUOROACRYLIC ACID AND PROCESSES FOR THE PREPARATION THEREOF
    Publication number: 20180072833
    Abstract: The present invention is directed to crosslinked cation exchange polymers comprising a fluoro group and an acid group and being a polymerization product of at least three monomers. Pharmaceutical compositions of these polymers are useful to bind potassium in the gastrointestinal tract.
    Type: Application
    Filed: November 17, 2017
    Publication date: March 15, 2018
    Inventors: Han-Ting Chang, Dominique Charmot, Mingjun Liu, Werner Strüver
  • TREATING HYPERKALEMIA WITH CROSSLINKED CATION EXCHANGE POLYMERS OF IMPROVED PHYSICAL PROPERTIES
    Publication number: 20170209481
    Abstract: The present invention is directed to methods of removing potassium or treating hyperkalemia by administering pharmaceutical compositions of crosslinked cation exchange polymers having beneficial physical properties, including combinations of particle size, particle shape, particle size distribution, viscosity, yield stress, compressibility, surface morphology, and/or swelling ratio.
    Type: Application
    Filed: December 16, 2016
    Publication date: July 27, 2017
    Inventors: Paul Mansky, Detlef Albrecht, Michael Burdick, Han-Ting Chang, Dominique Charmot, Eric Connor, Sherin Halfon, I-Zu Huang, Mingjun Liu, Werner Strüver
  • CROSSLINKED CATION EXCHANGE POLYMERS, COMPOSITIONS AND USE IN TREATING HYPERKALEMIA
    Publication number: 20170165292
    Abstract: The present invention is directed to crosslinked cation exchange polymers comprising a fluoro group and an acid group, pharmaceutical compositions of these polymers, compositions of a linear polyol and a salt of such polymer. Crosslinked cation exchange polymers having beneficial physical properties, including combinations of particle size, particle shape, particle size distribution, viscosity, yield stress, compressibility, surface morphology, and/or swelling ratio are also described. These polymers and compositions are useful to bind potassium in the gastrointestinal tract.
    Type: Application
    Filed: February 27, 2017
    Publication date: June 15, 2017
    Inventors: Paul Mansky, Detlef Albrecht, Michael Burdick, Han-Ting Chang, Dominique Charmot, Eric Connor, Sherin Halfon, I-Zu Huang, Mingjun Liu, Ramakrishnan Chidambaram, Jonathan Mills, Werner Strüver
  • Linear polyol stabilized polyfluoroacrylate compositions
    Patent number: 8337824
    Abstract: The present invention is directed to compositions of a linear polyol and a salt of a crosslinked cation exchange polymer comprising a fluoro group and an acid group. These compositions are useful to bind potassium in the gastrointestinal tract.
    Type: Grant
    Filed: August 22, 2009
    Date of Patent: December 25, 2012
    Assignee: Relypsa, Inc.
    Inventors: Detlef Albrecht, Michael Burdick, Han-Ting Chang, Dominique Charmot, Ramakrishnan Chidambaram, Eric Connor, Sherin Halfon, I-Zu Huang, Mingjun Liu, Jonathan Mills, Werner Strüver
  • CROSSLINKED CATION EXCHANGE POLYMERS, COMPOSITIONS AND USE IN TREATING HYPERKALEMIA
    Publication number: 20110236340
    Abstract: The present invention is directed to crosslinked cation exchange polymers comprising a fluoro group and an acid group, pharmaceutical compositions of these polymers, compositions of a linear polyol and a salt of such polymer. Crosslinked cation exchange polymers having beneficial physical properties, including combinations of particle size, particle shape, particle size distribution, viscosity, yield stress, compressibility, surface morphology, and/or swelling ratio are also described. These polymers and compositions are useful to bind potassium in the gastrointestinal tract.
    Type: Application
    Filed: August 22, 2009
    Publication date: September 29, 2011
    Applicant: Relypsa, Inc.
    Inventors: Paul Mansky, Detlef Albrecht, Michael Burdick, Han-Ting Chang, Dominique Charmot, Eric Connor, Sherin Halfon, I-Zu Huang, Mingjun Liu, Ramakrishnan Chidambaram, Jonathan Mills, Werner Strüver
  • CROSSLINKED POLYFLUOROACRYLIC ACID AND PROCESSES FOR THE PREPARATION THEREOF
    Publication number: 20100111892
    Abstract: The present invention is directed to crosslinked cation exchange polymers comprising a fluoro group and an acid group and being a polymerization product of at least three monomers. Pharmaceutical compositions of these polymers are useful to bind potassium in the gastrointestinal tract.
    Type: Application
    Filed: August 22, 2009
    Publication date: May 6, 2010
    Applicant: RELYPSA, INC.
    Inventors: Han-Ting Chang, Dominique Charmot, Mingjun Liu, Werner Strüver
  • LINEAR POLYOL STABILIZED POLYFLUOROACRYLATE COMPOSITIONS
    Publication number: 20100111891
    Abstract: The present invention is directed to compositions of a linear polyol and a salt of a crosslinked cation exchange polymer comprising a fluoro group and an acid group. These compositions are useful to bind potassium in the gastrointestinal tract.
    Type: Application
    Filed: August 22, 2009
    Publication date: May 6, 2010
    Applicant: RELYPSA, INC.
    Inventors: Detlef Albrecht, Michael Burdick, Han-Ting Chang, Dominique Charmot, Ramakrishnan Chidambaram, Eric Connor, Sherin Halfon, I-Zu Huang, Mingjun Liu, Jonathan Mills, Werner Strüver
  • TREATING HYPERKALEMIA WITH CROSSLINKED CATION EXCHANGE POLYMERS OF IMPROVED PHYSICAL PROPERTIES
    Publication number: 20100104527
    Abstract: The present invention is directed to methods of removing potassium or treating hyperkalemia by administering pharmaceutical compositions of crosslinked cation exchange polymers having beneficial physical properties, including combinations of particle size, particle shape, particle size distribution, viscosity, yield stress, compressibility, surface morphology, and/or swelling ratio.
    Type: Application
    Filed: August 22, 2009
    Publication date: April 29, 2010
    Applicant: RELYPSA, INC.
    Inventors: Paul Mansky, Detlef Albrecht, Michael Burdick, Han-Ting Chang, Dominique Charmot, Eric Connor, Sherin Halfon, I-Zu Huang, Mingjun Liu, Werner Strüver
  • Process for preparing monodisperse ion exchangers having chelating functional
    Patent number: 7077964
    Abstract: The present invention relates to a process for preparing novel, monodisperse ion exchangers having chelating functional groups, and their use for adsorbing metal compounds, in particular, heavy metal compounds and noble metal compounds, and also for extracting alkaline-earth metals from saline solutions from alkali metal chloride electrolysis.
    Type: Grant
    Filed: October 17, 2003
    Date of Patent: July 18, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Reinhold Klipper, Werner Strüver, Ulrich Schnegg, Bruno Hees, Bernhard Lehmann, Holger Lütjens
  • Process for preparing monodisperse anion exchangers
    Patent number: 7053129
    Abstract: The present invention relates to a process for preparing novel, monodisperse anion exchangers by (a) reacting monomer droplets made from monovinylaromatic compounds and polyvinylaromatic compounds, and optional porogens and/or initiators, (b) amidomethylating the resultant monodisperse, crosslinked bead polymers with phthalimide derivatives, (c) converting the amidomethylated bead polymers to aminomethylated bead polymers, and (d) alkylating the aminomethylated bead polymers.
    Type: Grant
    Filed: August 21, 2000
    Date of Patent: May 30, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Reinhold Klipper, Werner Strüver, Ulrich Schnegg, Rüdiger Seidel, Alfred Mitschker, Holger Lütjens
  • Process for preparing monodisperse ion exchangers having chelating functional groups and the use thereof
    Patent number: 6649663
    Abstract: The present invention relates to a process for preparing novel, monodisperse ion exchangers having chelating functional groups, and their use for adsorbing metal compounds, in particular, heavy metal compounds and noble metal compounds, and also for extracting alkaline-earth metals from saline solutions from alkali metal chloride electrolysis.
    Type: Grant
    Filed: August 21, 2000
    Date of Patent: November 18, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Reinhold Klipper, Werner Strüver, Ulrich Schnegg, Bruno Hees, Bernhard Lehmann, Holger Lütjens
  • Process for preparing monodisperse, crosslinked bead polymers having thiourea groups and their use for adsorbing metal compounds
    Patent number: 6329435
    Abstract: The present invention relates to a process for preparing novel, monodisperse crosslinked bead polymers having thiourea groups and their use for adsorbing metal compounds, in particular heavy metal compounds or noble metal compounds.
    Type: Grant
    Filed: August 21, 2000
    Date of Patent: December 11, 2001
    Assignee: Bayer Aktiengesellschaft
    Inventors: Reinhold Klipper, Werner Strüver, Ulrich Schnegg, Heiko Hoffmann, Dieter Mauer, Bernhard Lehmann, Bruno Hees, Holger Lütjens
  • Process for the preparation of microencapsulated polymers
    Patent number: 6251314
    Abstract: The present invention relates to a process for the preparation of microencapsulated polymers having a high surface smoothness, a soluble fraction of less than 6%, and a swelling index of between 1.3 and 9 by polymerizing a microencapsulated monomer mixture suspended in an aqueous phase containing at least one hydroxyaromatic compound as polymerization inhibitor, wherein the microencapsulated monomer mixture contains (a) 34 to 99.7% by weight of a monomer having one polymerizable C═C double bond, (b) 0.1 to 15% by weight of a crosslinking agent having at least 2 polymerizable C═C double bonds, (c) 0.2 to 1.0% by weight of at least one aliphatic peroxyester as polymerization initiator, and (d) 0 to 50% by weight of additives, the percentages being based on the sum of the components (a) to (c).
    Type: Grant
    Filed: June 4, 1999
    Date of Patent: June 26, 2001
    Assignee: Bayer Aktiengesellschaft
    Inventors: Olaf Halle, Werner Strüver, David Bryan Harrison, Wolfgang Podszun
  • Process for the preparation of crosslinked spherical polymers
    Patent number: 6221287
    Abstract: This invention relates to suspension polymers having high swellability have low contents of soluble fractions prepared using aliphatic peroxyesters as polymerization initiators.
    Type: Grant
    Filed: June 4, 1999
    Date of Patent: April 24, 2001
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Podszun, Olaf Halle, Werner Strüver, Robert Bloodworth, Holger Lütjens