Patents by Inventor Werner Zwerschke

Werner Zwerschke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9902763
    Abstract: The present invention relates to monoclonal anti-HPV (human papillomavirus) E7 antibodies capable of specifically recognizing an epitope of the C-terminal or the N-terminal region of a HPV E7 protein, diagnostic compositions and kits comprising said antibodies as well as methods for immunohistochemical and ELISA-based diagnosis of HPV infections utilizing said antibodies.
    Type: Grant
    Filed: January 6, 2016
    Date of Patent: February 27, 2018
    Assignees: OSTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN, AUSTRIA WIRTSCHAFTSSERVICE GESELLSCHAFT MBH
    Inventors: Pidder Jansen-Durr, Werner Zwerschke, Haymo Pircher, Daniela Ehehalt, Barbara Lener, Kerstin Dreier
  • Publication number: 20160237143
    Abstract: The present invention relates to monoclonal anti-HPV (human papillomavirus) E7 antibodies capable of specifically recognising an epitope of the C-terminal or the N-terminal region of a HPV E7 protein, diagnostic compositions and kits comprising said antibodies as well as methods for immunohistochemical and ELISA-based diagnosis of HPV infections utilizing said antibodies.
    Type: Application
    Filed: January 6, 2016
    Publication date: August 18, 2016
    Inventors: Pidder Jansen-Durr, Werner Zwerschke, Haymo Pircher, Daniela Ehehalt, Barbara Lener, Kerstin Dreier
  • Patent number: 9249212
    Abstract: Monoclonal anti-HPV (human papillomavirus) E7 antibodies are capable of specifically recognizing an epitope of the C-terminal or the N-terminal region of a HPV E7 protein.
    Type: Grant
    Filed: February 16, 2011
    Date of Patent: February 2, 2016
    Assignees: OSTERREICHISCHE AKADEMIE DER WISSENCHAFTEN, AUSTRIA WIRTSCHAFTSSERVICE GESELLSCHAFT MBH
    Inventors: Pidder Jansen-Dürr, Werner Zwerschke, Haymo Pircher, Daniela Ehehalt, Barbara Lener, Kerstin Dreier
  • Publication number: 20130029322
    Abstract: Monoclonal anti-HPV (human papillomavirus) E7 antibodies are capable of specifically recognizing an epitope of the C-terminal or the N-terminal region of a HPV E7 protein.
    Type: Application
    Filed: February 16, 2011
    Publication date: January 31, 2013
    Applicants: AUSTRIA WIRTSCHAFTSSERVICE GESELLSCHAFT MBH, ÖSTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN
    Inventors: Pidder Jansen-Dürr, Werner Zwerschke, Haymo Pircher, Daniela Ehehalt, Barbara Lener, Kerstin Dreier
  • Publication number: 20070166699
    Abstract: The present invention relates to a combination of antibodies comprising (a) an anti-HPV-16 E7 antibody obtainable by (i) eliciting an in vivo humoral response against HPV-16 E7 protein or a fragment thereof in a goat; and (ii) affinity-purifying antibodies as obtained in the eliciting-step (i) and (b) an anti-HPV-18 E7 antibody. Additionally, in another aspect the present invention relates to methods for producing said combination of antibodies. Furthermore, the invention provides for the use of the combination of antibodies or for the use of an anti-HPV-16 E7 antibody obtainable as mentioned above for the preparation of a diagnostic composition for the (immuno-) histological detection of high risk HPV in a biological sample. Additionally, the invention relates to diagnostic compositions comprising said combination of antibodies or said anti-HPV-16 E7 antibody obtainable as mentioned above as well as to methods for producing said diagnostic compositions.
    Type: Application
    Filed: September 17, 2004
    Publication date: July 19, 2007
    Inventors: Werner Zwerschke, Pidder Jansen-Duerr, Marc Fiedler, Andreas Laich, Barbara Fitzky
  • Publication number: 20060147906
    Abstract: The present invention relates to an anti-HPV-16 E7 antibody obtainable by (a) eliciting an in vivo humoral response against highly purified HPV-16 E7 protein or a fragment thereof in a non-human vertebrate; and (b) affinity-purifying antibodies as obtained in the eliciting-step (a). Furthermore, the invention provides for the use of the anti-HPV-1 E7 antibody/antibodies for the preparation of a diagnostic composition of the (immuno-)histological detection of expressed HPV-16 E7 in a biological sample. Additionally, the invention relates to specific diagnostic compositions as well as to methods producing the same. The invention also provides for kits comprising (an) anti-HPV-16 E7 antibody(ies) of the invention or a diagnostic composition and discloses in vitro methods for the detection of a sexually transmittable disease or cancer, in particular cervical cancer, breast cancer, prostate cancer, anogenital cancer/neoplasia, penile cancer or head and neck cancer by using the described antibodies.
    Type: Application
    Filed: March 21, 2003
    Publication date: July 6, 2006
    Applicant: Amynon Biotech GmbH
    Inventors: Werner Zwerschke, Pidder Jansen-Duerr, Marc Fiedler, Johann Viertler, Andreas Widschwendter, Elisabeth Mueller-Holzner, Andreas Laich, Barhard Fitzky