Abstract: In some embodiments, novel approaches to processing bioinformatics data are used wherein the input data is divided into many small pieces that are processed in parallel by serverless functions. In effect, the functions can be used as on-demand compute units to form an affordable public-cloud version of a supercomputer. Some embodiments of the present disclosure can be used to accelerate the alignment of a single dataset. In some embodiments, the process of setting up the cloud infrastructure is automated so that the user need only to enter credentials from the cloud account. In some embodiments, these improvements are incorporated into an accessible and containerized graphical front-end that allows the user to use a browser to execute, monitor and modify all steps of the analyses from alignment to the display of the resulting differentially expressed genes.