Patents by Inventor Wesley Kwan Mung Chong

Wesley Kwan Mung Chong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nitric oxide donating prostamides
    Patent number: 8101658
    Abstract: Nitroderivatives of prostaglandins having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension.
    Type: Grant
    Filed: May 11, 2009
    Date of Patent: January 24, 2012
    Assignee: Nicox S.A.
    Inventors: Francesca Benedini, Stefano Biondi, Valerio Chiroli, Wesley Kwan Mung Chong, Liming Dong, Achim Hans-Peter Krauss, Fabio Nicoli, Ganesh Prasanna, William Francois Vernier, Yi Yang
  • NITRIC OXIDE DONATING PROSTAMIDES
    Publication number: 20110092590
    Abstract: Nitroderivatives of prostaglandins having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension.
    Type: Application
    Filed: May 11, 2009
    Publication date: April 21, 2011
    Applicant: NICOX S.A.
    Inventors: Francesca Benedini, Stefano Biondi, Valerio Chiroli, Wesley Kwan Mung Chong, Liming Dong, Achim Hans-Peter Krauss, Fabio Nicoli, Ganesh Prasanna, William Francois Vernier, Yi Yang
  • HETEROCYCLES USEFUL AS INHIBITORS OF CARBONIC ANHYDRASE
    Publication number: 20100256357
    Abstract: Sulfonamides and pharmaceutical compositions containing the compounds useful in controlling intraocular pressure are disclosed. Methods for controlling intraocular pressure through administration of the compositions are also disclosed.
    Type: Application
    Filed: July 30, 2007
    Publication date: October 7, 2010
    Inventors: Wesley Kwan Mung Chong, Andrew M. Haidle, Martha Alicia Ornelas, Lin Li, Seiji Nukui, Eugene Yuanjin Rui, Min Teng, William Francois Vernier, Joe Zhongxiang Zhou
  • Quinoxaline derivatives of alpha-2 adrenergic agonists
    Patent number: 7799784
    Abstract: The present invention relates to alpha2-adrenergic receptor agonist nitrooxyderivatives, including the following structure, having improved pharmacological activity and enhanced tolerability. They can be employed for the treatment of ocular diseases, in particular high intraocular pressure and glaucoma.
    Type: Grant
    Filed: February 2, 2007
    Date of Patent: September 21, 2010
    Assignee: Nicox S.A.
    Inventors: Francesca Benedini, Francesco Impagnatiello, Stefano Biondi, Ennio Ongini, Wesley Kwan Mung Chong
  • Prostaglandin derivatives
    Patent number: 7718656
    Abstract: Nitroderivatives of prostaglandin amides having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension.
    Type: Grant
    Filed: June 28, 2006
    Date of Patent: May 18, 2010
    Assignee: Nicox S.A.
    Inventors: Francesca Benedini, Valerio Chiroli, Wesley Kwan Mung Chong, Achim Hans-Peter Krauss, Michael Ross Niesman, Ennio Ongini
  • Prostaglandin derivatives
    Publication number: 20090062296
    Abstract: Nitroderivatives of prostaglandin amides having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension.
    Type: Application
    Filed: June 28, 2006
    Publication date: March 5, 2009
    Inventors: Francesca Benedini, Valerio Chiroli, Wesley Kwan Mung Chong, Achim Hans-Peter Krauss, Michael Ross Niesman, Ennio Ongini
  • Derivatives of Alpha2-Adrenergic Receptor Agonist
    Publication number: 20080318965
    Abstract: The present invention relates to alpha2-adrenergic receptor agonist nitrooxyderivatives having improved pharmacological activity and enhanced tolerability. They can be employed for the treatment of ocular diseases, in particular high intraocular pressure and glaucoma.
    Type: Application
    Filed: February 2, 2007
    Publication date: December 25, 2008
    Inventors: Francesca Benedini, Francesco Impagnatiello, Stefano Biondi, Ennio Ongini, Wesley Kwan Mung Chong
  • Thiazole benzamide derivatives and pharmaceutical compositions for inhibiting cell proliferation
    Patent number: 6720346
    Abstract: Aminothiazole compounds with mono-/di-substituted benzamide are represented by the Formula (I), and their pharmaceutically acceptable salts, pharmaceutically acceptable prodrugs, pharmaceutically active metabolites, and pharmaceutically acceptable salts of said metabolites are described. These agents modulate and/or inhibit the cell proliferation and activity of protein kinases and are useful as pharmaceuticals for treating malignancies and other disorders.
    Type: Grant
    Filed: July 5, 2002
    Date of Patent: April 13, 2004
    Assignee: Agouron Pharmaceuticals, Inc.
    Inventors: Shao Song Chu, Larry Andrew Alegria, Ted Michael Bleckman, Wesley Kwan Mung Chong, Rohit K. Duvadie, Lin Li, Siegfried Heinz Reich, William Henry Romines, III, Michael B. Wallace, Yi Yang
  • Thiazole benzamide derivatives and pharmaceutical compositions for inhibiting cell proliferation, and methods for their use
    Publication number: 20030225147
    Abstract: Aminothiazole compounds with mono-/di-substituted benzamide are represented by the Formula (I), and their pharmaceutically acceptable salts, pharmaceutically acceptable prodrugs, pharmaceutically active metabolites, and pharmaceutically acceptable salts of said metabolites are described.
    Type: Application
    Filed: July 5, 2002
    Publication date: December 4, 2003
    Inventors: Shao Song Chu, Larry Andrew Alegria, Ted Michael Bleckman, Wesley Kwan Mung Chong, Rohit K. Duvadie, Lin Li, Siegfried Heinz Reich, William Henry Romines, Michael B. Wallace, Yi Yang
  • Pyrazole-thiazole compounds, pharmaceutical compositions containing them
    Patent number: 6566363
    Abstract: Pyrazole-thiazole compounds that modulate and/or inhibit the activity of cyclin-dependent kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating cyclin-dependent diseases to modulate and/or inhibit unwanted cell proliferation. The invention is also directed to the therapeutic or prophylactic use of pharmaceutical compositions containing such compounds, and to methods of treating cancer as well as other disease states associated with unwanted angiogenesis and/or cellular proliferation, such as diabetic retinopathy, glaucoma, rheumatoid arthritis, and psoriasis, by administering effective amounts of such compounds.
    Type: Grant
    Filed: August 8, 2001
    Date of Patent: May 20, 2003
    Assignee: Agouron Pharmaceuticals, Inc.
    Inventors: Wesley Kwan Mung Chong, Rohit Kumar Duvadie
  • Pyrazole-thiazole compounds, pharmaceutical compositions containing them, and methods of their use for inhibiting cyclin-dependent kinases
    Publication number: 20020049215
    Abstract: Pyrazole-thiazole compounds that modulate and/or inhibit the activity of cyclin-dependent kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating cyclin-dependent diseases to modulate and/or inhibit unwanted cell proliferation. The invention is also directed to the therapeutic or prophylactic use of pharmaceutical compositions containing such compounds, and to methods of treating cancer as well as other disease states associated with unwanted angiogenesis and/or cellular proliferation, such as diabetic retinopathy, glaucoma, rheumatoid arthritis, and psoriasis, by administering effective amounts of such compounds.
    Type: Application
    Filed: August 8, 2001
    Publication date: April 25, 2002
    Inventors: Wesley Kwan Mung Chong, Rohit Kumar Duvadie