Patents by Inventor Wesley R. Anderson

Wesley R. Anderson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20040110735
    Abstract: The present invention relates to amphiphilic drug-oligomer conjugates capable of traversing the blood-brain barrier (“BBB”) and to methods of making and using such conjugates. An amphiphilic drug-oligomer conjugate comprises a therapeutic compound conjugated to an oligomer, wherein the oligomer comprises a lipophilic moiety coupled to a hydrophilic moiety. The conjugates of the invention further comprise therapeutic agents such as proteins, peptides, nucleosides, nucleotides, antiviral agents, antineoplastic agents, antibiotics, etc., and prodrugs, precursors, derivatives and intermediates thereof, chemically coupled to amphiphilic oligomers.
    Type: Application
    Filed: November 19, 2003
    Publication date: June 10, 2004
    Inventors: Nnochiri N. Ekwuribe, Balasingam Radhakrishnan, Christopher H. Price, Wesley R. Anderson, Aslam M. Ansari
  • Publication number: 20040102381
    Abstract: The present invention relates to amphiphilic drug-oligomer conjugates capable of traversing the blood-brain barrier (“BBB”) and to methods of making and using such conjugates. An amphiphilic drug-oligomer conjugate comprises a therapeutic compound conjugated to an oligomer, wherein the oligomer comprises a lipophilic moiety coupled to a hydrophilic moiety. The conjugates of the invention further comprise therapeutic agents such as proteins, peptides, nucleosides, nucleotides, antiviral agents, antineoplastic agents, antibiotics, etc., and prodrugs, precursors, derivatives and intermediates thereof, chemically coupled to amphiphilic oligomers.
    Type: Application
    Filed: November 19, 2003
    Publication date: May 27, 2004
    Inventors: Nnochiri N. Ekwuribe, Balasingam Radhakrishnan, Christopher H. Price, Wesley R. Anderson, Aslam M. Ansari
  • Patent number: 4863911
    Abstract: The invention provides a method for treating sexual dysfunction in male mammals using a compound of the formula[E--DHC] (I)or a non-toxic pharmaceutically acceptable salt thereof, wherein [E] is an estrogen and [DHC] is the reduced, biooxidizable, blood-brain barrier-penetrating, lipoidal form of a dihydropridine.revreaction.pyridinium salt redox carrier. Compositions for use in the subject method are also disclosed. A preferred compound for use in the method and compositions is an estradiol derivative, namely, 17.beta.-[(1-methyl-1,4-dihydro-3-pyridinyl)carbonyloxy]estra-1,3,5(10)-tr ien-3-ol.
    Type: Grant
    Filed: August 4, 1986
    Date of Patent: September 5, 1989
    Assignee: University of Florida
    Inventors: Wesley R. Anderson, Jr., Nicholas S. Bodor, James W. Simpkins