Patents by Inventor Wessel Lageweg

Wessel Lageweg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Production of antimicrobial proteins in fusion proteins
    Patent number: 7785828
    Abstract: The invention relates to a method of producing cysteine containing polypeptides in fusion proteins by recombinantly expressing in a host cell sequences encoding an antifungal polypeptide, a maltose binding protein, and a histidine tag. The method is carried out in the presence of a reducing agent to prevent misfolding of the fusion proteins.
    Type: Grant
    Filed: February 6, 2004
    Date of Patent: August 31, 2010
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Gusui Wu, Wessel Lageweg, Maarten H. Stuiver, Lu Liu, Wei Wei, Michael A. Dojka, Jr., Linda K. Dojka, legal representative
  • Antifungal proteins, DNA coding therefore, and hosts incorporating same
    Patent number: 6864076
    Abstract: The present invention provides an isolated protein obtainable from a plant source which has antifungal activity, specifically anti-Phytophthora activity and/or anti-Pythium activity and a molecular weight of about 55-65 kDa as judged by SDS PAGE-electrophoresis, an isolated DNA sequence comprising an open reading frame capable of encoding a protein according to the invention, preferably characterized in that it comprises an open reading frame which is capable of encoding a protein depicted in SEQ ID NO. 16, SEQ ID NO. 57, SEQ ID NO. 70, SEQ ID NO. 72 or SEQ ID NO. 74 or muteins thereof, and DNA capable of hybridizing therewith under stringent conditions. The invention further comprises plants incorporating chimeric DNA capable of encoding a protein according to the invention, and wherein the protein is expressed. Also shown is the carbohydrate and preferably hexose oxidating activity of said protein.
    Type: Grant
    Filed: February 25, 1999
    Date of Patent: March 8, 2005
    Assignee: Syngenta Mogen B.V.
    Inventors: Maarten Hendrik Stuiver, Jerome Hubertus Henricus Victor Custers, Marianne Beatrix Sela-Buurlage, Leo Sjoerd Melchers, Wessel Lageweg, Anne Silene Ponstein, Johanna Pieternella Els Van Deventer-Troost
  • ANTIFUNGAL PROTEINS, DNA CODING THEREFORE, AND HOSTS INCORPORATING SAME
    Publication number: 20020168735
    Abstract: The present invention provides an isolated protein obtainable from a plant source which has antifungal activity, specifically anti-Phytophthora activity and/or anti-Pythium activity and a molecular weight of about 55-65 kDa as judged by SDS PAGE-electrophoresis, an isolated DNA sequence comprising an open reading frame capable of encoding a protein according to the invention, preferably characterized in that it comprises an open reading frame which is capable of encoding a protein depicted in SEQ ID NO. 16, SEQ ID NO. 57, SEQ ID NO. 70, SEQ ID NO. 72 or SEQ ID NO. 74 or muteins thereof, and DNA capable of hybridizing therewith under stringent conditions The invention further comprises plants incorporating chimeric DNA capable of encoding a protein according to the invention and wherein the protein is expressed. Also shown is the carbohydrate and preferably hexose oxidating activity of said protein.
    Type: Application
    Filed: February 25, 1999
    Publication date: November 14, 2002
    Inventors: MAARTEN HENDRIK STUIVER, JEROME HUBERTUS HENRICUS VICTOR CUSTERS, MARIANNE BEATRIX SELA-BUURLAGE, LEO SJOERD MELCHERS, WESSEL LAGEWEG, ANNE SILENE PONSTEIN, JOHANNA PIETERNELLA ELS VAN DEVENTER-TROOST