Patents by Inventor Weston K. Kightlinger

Weston K. Kightlinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protein glycosylation sites by rapid expression and characterization of N-glycosyltransferases
    Patent number: 11898187
    Abstract: Disclosed are components, systems, and methods for glycoprotein or recombinant glycoprotein protein synthesis in vitro and in vivo. In particular, the present invention relates to components, systems, and methods for identifying amino acid glycosylation tag motifs for N-glycosyltransferases and the use of the identified amino acid glycosylation tag motifs in methods for preparing glycoproteins and recombinant glycoproteins in vitro and in vivo.
    Type: Grant
    Filed: August 15, 2018
    Date of Patent: February 13, 2024
    Assignee: Northwestern University
    Inventors: Michael Christopher Jewett, Weston K. Kightlinger, Liang Lin, Milan Mrksich
  • Design of Protein Glycosylation Sites by Rapid Expression and Characterization of N-Glycosyltransferases
    Publication number: 20220235389
    Abstract: Disclosed are components, systems, and methods for glycoprotein or recombinant glycoprotein protein synthesis in vitro and in vivo. In particular, the present invention relates to components, systems, and methods for identifying amino acid glycosylation tag motifs for N-glycosyltransferases and the use of the identified amino acid glycosylation tag motifs in methods for preparing glycoproteins and recombinant glycoproteins in vitro and in vivo.
    Type: Application
    Filed: August 15, 2018
    Publication date: July 28, 2022
    Applicant: Northwestern University
    Inventors: Michael Christopher Jewett, Weston K. Kightlinger, Liang Lin, Milan Mrksich
  • PLATFORM FOR PRODUCING GLYCOPROTEINS, IDENTIFYING GLYCOSYLATION PATHWAYS
    Publication number: 20220186276
    Abstract: Disclosed are components, systems, and methods for glycoprotein protein synthesis in vitro and in vivo. In particular, the disclosed components, systems, and methods relate to modular platforms for producing glycoproteins. The components, systems, and methods disclosed herein may be used in synthesizing glycoproteins and recombinant glycoproteins in cell-free protein synthesis (CFPS) and in modified cells.
    Type: Application
    Filed: January 25, 2019
    Publication date: June 16, 2022
    Inventors: Michael C. Jewett, Weston K. Kightlinger