Patents by Inventor Whitney Shatz

Whitney Shatz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRODUCTION OF HETEROMULTIMERIC PROTEINS USING MAMMALIAN CELLS
    Publication number: 20220002386
    Abstract: Described herein are methods for the efficient production of antibodies and other multimeric protein complexes (collectively referred to herein as heteromultimeric proteins) capable of specifically binding to more than one target. The targets may be, for example, different epitopes located on a single molecule or located on different molecules.
    Type: Application
    Filed: February 9, 2021
    Publication date: January 6, 2022
    Applicant: Genentech, Inc.
    Inventors: Justin SCHEER, Whitney SHATZ, Domingos NG
  • Anti-factor D antibody variant conjugates and uses thereof
    Patent number: 10961313
    Abstract: The disclosure relates to antibody-polymer conjugates comprising one or more anti-Factor D antibody variants, their production and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation.
    Type: Grant
    Filed: December 30, 2019
    Date of Patent: March 30, 2021
    Assignee: Genentech, Inc.
    Inventors: Philip E. Hass, Robert F. Kelley, Justin M. Scheer, Whitney Shatz, Devin Tesar, Menno van Lookeren Campagne
  • Production of heteromultimeric proteins using mammalian cells
    Patent number: 10941190
    Abstract: Described herein are methods for the efficient production of antibodies and other multimeric protein complexes (collectively referred to herein as heteromultimeric proteins) capable of specifically binding to more than one target. The targets may be, for example, different epitopes located on a single molecule or located on different molecules.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: March 9, 2021
    Assignee: Genentech, Inc.
    Inventors: Justin Scheer, Whitney Shatz, Domingos Ng
  • Anti-factor D antibody variant conjugates and uses thereof
    Patent number: 10654932
    Abstract: The disclosure relates to antibody-polymer conjugates comprising one or more anti-Factor D antibody variants, their production and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation.
    Type: Grant
    Filed: October 27, 2016
    Date of Patent: May 19, 2020
    Assignee: Genentech, Inc.
    Inventors: Philip E. Hass, Robert F. Kelley, Justin M. Scheer, Whitney Shatz, Devin Tesar, Menno van Lookeren Campagne
  • ANTI-FACTOR D ANTIBODY VARIANT CONJUGATES AND USES THEREOF
    Publication number: 20200115462
    Abstract: The disclosure relates to antibody-polymer conjugates comprising one or more anti-Factor D antibody variants, their production and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation.
    Type: Application
    Filed: December 30, 2019
    Publication date: April 16, 2020
    Inventors: Philip E. Hass, Robert F. Kelley, Justin M. Scheer, Whitney Shatz, Devin Tesar, Menno van Lookeren Campagne
  • Anti-factor D antibodies and conjugates
    Patent number: 10407510
    Abstract: The invention provides anti-Factor D antibodies and conjugates and methods of using the same.
    Type: Grant
    Filed: October 27, 2016
    Date of Patent: September 10, 2019
    Assignee: Genentech, Inc.
    Inventors: Robert F. Kelley, Whitney Shatz, Devin Tesar, Justin M. Scheer, Michelle Dion
  • SYSTEMS AND METHODS FOR PREDICTING VITREAL HALF-LIFE OF THERAPEUTIC AGENT-POLYMER CONJUGATES
    Publication number: 20180293360
    Abstract: Disclosed are systems and methods for estimating the vitreal half-life of a therapeutic agent. In particular, systems and methods are disclosed for predicting the vitreal half-life of a therapeutic agent conjugated to a polymer that make use of an empirically-derived relationship of vitreal half-life to the hydrodynamic radius of a candidate therapeutic agent-polymer conjugate. The present disclosure is further directed to the use of the systems and methods disclosed herein to design a candidate therapeutic agent-polymer conjugate with a preselected vitreal half-life.
    Type: Application
    Filed: October 5, 2016
    Publication date: October 11, 2018
    Inventors: Robert Kelley, Justin Scheer, Whitney Shatz
  • ANTI-IL-13/IL-17 BISPECIFIC ANTIBODIES AND USES THEREOF
    Publication number: 20170334985
    Abstract: The invention provides anti-IL-13/IL-17 bispecific antibodies, in particular, anti-IL13/IL17 AA, AF and FF antibodies and methods of using the same, including without limitation, methods of using the anti-IL-13/IL-17 bispecific antibodies for treating moderate to severe asthma and/or eosinophilic asthma.
    Type: Application
    Filed: February 23, 2017
    Publication date: November 23, 2017
    Applicant: Genentech, Inc.
    Inventors: LAWREN WU, JOSEPH R. ARRON, MICHAEL DILLON, DAVID F. CHOY, SUE SOHN, CHRISTOPH SPIESS, WHITNEY SHATZ
  • PRODUCTION OF HETEROMULTIMERIC PROTEINS USING MAMMALIAN CELLS
    Publication number: 20170260252
    Abstract: Described herein are methods for the efficient production of antibodies and other multimeric protein complexes (collectively referred to herein as heteromultimeric proteins) capable of specifically binding to more than one target. The targets may be, for example, different epitopes located on a single molecule or located on different molecules.
    Type: Application
    Filed: November 4, 2016
    Publication date: September 14, 2017
    Applicant: Genentech, Inc.
    Inventors: JUSTIN SCHEER, WHITNEY SHATZ, DOMINGOS NG
  • ANTI-FACTOR D ANTIBODY VARIANT CONJUGATES AND USES THEREOF
    Publication number: 20170143843
    Abstract: The disclosure relates to antibody-polymer conjugates comprising one or more anti-Factor D antibody variants, their production and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation.
    Type: Application
    Filed: October 27, 2016
    Publication date: May 25, 2017
    Inventors: Philip E. Hass, Robert F. Kelley, Justin M. Scheer, Whitney Shatz, Devin Tesar, Menno van Lookeren Campagne
  • ANTI-FACTOR D ANTIBODIES AND CONJUGATES
    Publication number: 20170145112
    Abstract: The invention provides anti-Factor D antibodies and conjugates and methods of using the same.
    Type: Application
    Filed: October 27, 2016
    Publication date: May 25, 2017
    Applicant: GENENTECH, INC.
    Inventors: Robert F. Kelley, Whitney Shatz, Devin Tesar, Justin M. Scheer, Michelle Dion