Patents by Inventor Wieslaw M. Kazmierski

Wieslaw M. Kazmierski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE
    Publication number: 20200291008
    Abstract: Provided are IDO1 inhibitor compounds of Formula I and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and methods for their use in the prevention and/or treatment of diseases.
    Type: Application
    Filed: November 28, 2018
    Publication date: September 17, 2020
    Inventors: Wieslaw M. KAZMIERSKI, John G. CATALANO, Pek Y. CHONG
  • Prodrugs of aspartyl protease inhibitors
    Publication number: 20030144217
    Abstract: The present invention relates to prodrugs of a class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of prodrugs of HIV aspartyl protease inhibitors characterized by favorable aqueous solubility, high oral bioavailability and facile in vivo generation of the active ingredient. This invention also relates to pharmaceutical compositions comprising these prodrugs. The prodrugs and pharmaceutical compositions of this invention are particularly well suited for decreasing the pill burden and increasing patient compliance. This invention also relates to methods of treating mammals with these prodrugs and pharmaceutical compositions.
    Type: Application
    Filed: August 21, 2002
    Publication date: July 31, 2003
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Roger D. Tung, Michael R. Hale, Christopher T. Baker, Andrew Spaltenstein, Eric S. Furfine, Istvan Kaldor, Wieslaw M. Kazmierski