Patents by Inventor Wieslaw Mieczyslaw Kazmierski

Wieslaw Mieczyslaw Kazmierski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds and methods for treating HIV
    Patent number: 9163023
    Abstract: Provided are compounds and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and their use for treating viral infections mediated by a member of the retrovirus family of viruses such as the Human Immunodeficiency Virus (HIV).
    Type: Grant
    Filed: July 10, 2013
    Date of Patent: October 20, 2015
    Assignee: ViiV Healthcare UK Limited
    Inventors: Martha Alicia De La Rosa, Brian Alvin Johns, Wieslaw Mieczyslaw Kazmierski, Vicente Samano, Lita Suwandi, David Temelkoff, Emile Velthuisen, Jason Gordon Weatherhead
  • COMPOUNDS AND METHODS FOR TREATING HIV
    Publication number: 20150191469
    Abstract: Provided are compounds and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and their use for treating viral infections mediated by a member of the retrovirus family of viruses such as the Human Immunodeficiency Virus (HIV).
    Type: Application
    Filed: July 10, 2013
    Publication date: July 9, 2015
    Inventors: Martha Alicia De La Rosa, Brian Alvin Johns, Wieslaw Mieczyslaw Kazmierski, Vicente Samano, Lita Suwandi, David Temelkoff, Emile Velthuisen, Jason Gordon Weatherhead
  • Chemica compounds
    Patent number: 8889726
    Abstract: Disclosed are compounds of Formula I, Formula II, and Formula III. Also disclosed are salts of the compounds, pharmaceutical composition comprising the compounds or salts, and methods for treating HCV infection by administration of the compounds or salts.
    Type: Grant
    Filed: August 6, 2012
    Date of Patent: November 18, 2014
    Assignee: GlaxoSmithKline LLC
    Inventors: Subramanian Baskaran, Richard Martin Grimes, Wieslaw Mieczyslaw Kazmierski, Martin Robert Leivers
  • Chemical Compounds
    Publication number: 20140171476
    Abstract: Disclosed are compounds of Formula I, Formula II, and Formula III. Also disclosed are salts of the compounds, pharmaceutical composition comprising the compounds or salts, and methods for treating HCV infection by administration of the compounds or salts.
    Type: Application
    Filed: August 6, 2012
    Publication date: June 19, 2014
    Applicant: GlaxoSmith Kline LLC
    Inventors: Subramanian Baskaran, Richard Martin Grimes, Wieslaw Mieczyslaw Kazmierski, Martin Robert Leivers
  • Therapeutic compounds
    Patent number: 8592395
    Abstract: The present invention relates to compounds of Formula (I) and (Ia) useful in the treatment of CCR5-related diseases and disorders, for example, the prevention or treatment of an HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).
    Type: Grant
    Filed: July 23, 2010
    Date of Patent: November 26, 2013
    Assignee: GlaxoSmithKline LLC
    Inventors: Maosheng Duan, Wieslaw Mieczyslaw Kazmierski, Matthew Tallant
  • Chemical compounds
    Patent number: 8492554
    Abstract: Disclosed are compounds of Formula III. Also disclosed are salts of the compounds, pharmaceutical composition comprising the compounds or salts, and methods for treating HCV infection by administration of the compounds or salts.
    Type: Grant
    Filed: November 15, 2012
    Date of Patent: July 23, 2013
    Assignee: GlaxoSmithKline LLC
    Inventors: Pingyun Chen, Ricky Couch, Maosheng Duan, Richard Martin Grimes, Wieslaw Mieczyslaw Kazmierski, Beth Adams Norton, Matthew Tallant
  • Therapeutic Compounds
    Publication number: 20120295877
    Abstract: The present invention relates to compounds of Formula (I) and (Ia) useful in the treatment of CCR5-related diseases and disorders, for example, the prevention or treatment of an HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).
    Type: Application
    Filed: July 23, 2010
    Publication date: November 22, 2012
    Inventors: Maosheng Duan, Wieslaw Mieczyslaw Kazmierski, Matthew Tallant
  • Chemical Compounds
    Publication number: 20110152237
    Abstract: Disclosed are compounds of Formula III. Also disclosed are salts of the compounds, pharmaceutical composition comprising the compounds or salts, and methods for treating HCV infection by administration of the compounds or salts.
    Type: Application
    Filed: August 26, 2010
    Publication date: June 23, 2011
    Inventors: Pingyun Chen, Ricky Couch, Maosheng Duan, Richard Martin Grimes, Wieslaw Mieczyslaw Kazmierski, Beth Adams Norton, Matthew Tallant, Pingyun Chen, Ricky Couch, Maosheng Duan, Richard Martin Grimes, Wleslaw Mieczyslaw Kazmierski, Beth Adams Norton, Matthew Tallant
  • CCR5 antagonists as therapeutic agents
    Patent number: 7645771
    Abstract: The present invention relates to compounds of formula (I) or a pharmaceutically acceptable derivatives thereof, useful in the treatment of prophylazis of CCR5-related diseases and disorders, for example, in the inhibition of HIV replication, the prevention or treatment of HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).
    Type: Grant
    Filed: December 12, 2003
    Date of Patent: January 12, 2010
    Assignee: SmithKline Beecham Corp.
    Inventors: Wieslaw Mieczyslaw Kazmierski, Chrisopher Joseph Aquino, Neil Bifulco, Eric Eugene Boros, Brian Andrew Chauder, Pek Yoke Chong, Maosheng Duan, Felix Deanda, Jr., Cecilia Suarez Koble, Ed Williams McLean, Jennifer Poole Peckham, Angilique C Perkins, James Benjamin Thompson, Dana Vanderwall
  • Cyclohexyl compounds as CCR5 antagonists
    Patent number: 7589207
    Abstract: The present invention relates to compounds of formula (I), or pharmaceutically acceptable derivatives thereof, useful in the treatment of CCR5-related diseases and disorders, for example, useful in the inhibition of HIV replication, the prevention or treatment of an HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).
    Type: Grant
    Filed: December 12, 2003
    Date of Patent: September 15, 2009
    Assignee: SmithKline Beecham Corporation
    Inventors: Maosheng Duan, Wieslaw Mieczyslaw Kazmierski, Christopher Joseph Aquino
  • Indane compounds as CCR5 antagonists
    Patent number: 7589204
    Abstract: The present invention relates to compounds of formula (I), or pharmaceutically acceptable derivatives thereof, useful in the treatment of CCR5-related diseases and disorders, for example, useful in the inhibition of HIV replication, the prevention or treatment of an HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).
    Type: Grant
    Filed: April 1, 2009
    Date of Patent: September 15, 2009
    Assignee: SmithKline Beecham Corporation
    Inventors: Michael Youngman, Wieslaw Mieczyslaw Kazmierski, Hanbiao Yang, Christopher Joseph Aquino
  • Cyclopropyl compounds as ccr5 antagonists
    Patent number: 7569579
    Abstract: The present invention relates to compounds of formula (I), or pharmaceutically acceptable derivatives thereof, useful in the treatment of CCR5-related diseases and disorders, for example, useful in the inhibition of HIV replication, the prevention or treatment of an HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).
    Type: Grant
    Filed: December 12, 2003
    Date of Patent: August 4, 2009
    Assignee: SmithKline Beecham Corporation
    Inventors: Jennifer Poole Peckham, Christopher Joseph Aquino, Wieslaw Mieczyslaw Kazmierski
  • INDANE COMPOUNDS AS CCR5 ANTAGONISTS
    Publication number: 20090187021
    Abstract: The present invention relates to compounds of formula (I), or pharmaceutically acceptable derivatives thereof, useful in the treatment of CCR5-related diseases and disorders, for example, useful in the inhibition of HIV replication, the prevention or treatment of an HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).
    Type: Application
    Filed: April 1, 2009
    Publication date: July 23, 2009
    Inventors: Michael YOUNGMAN, Wieslaw Mieczyslaw KAZMIERSKI, Hanbiao YANG, Christopher Joseph AQUINO
  • Indane compounds as CCR5 antagonists
    Patent number: 7531661
    Abstract: The present invention relates to compounds of formula (I), or pharmaceutically acceptable derivatives thereof, useful in the treatment of CCR5-related diseases and disorders, for example, useful in the inhibition of HIV replication, the prevention or treatment of an HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).
    Type: Grant
    Filed: December 12, 2003
    Date of Patent: May 12, 2009
    Assignee: SmithKline Beecham Corporation
    Inventors: Michael Youngman, Wieslaw Mieczyslaw Kazmierski, Hanbiao Yang, Christopher Joseph Aquino
  • HETEROCYCLIC COMPOUNDS AS CCR5 ANTAGONISTS
    Publication number: 20090053172
    Abstract: The present invention relates to compounds of formula (I), or pharmaceutically acceptable derivatives thereof, useful in the treatment of CCR5-related diseases and disorders, for example, useful in the inhibition of HIV replication, the prevention or treatment of an HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).
    Type: Application
    Filed: October 15, 2008
    Publication date: February 26, 2009
    Inventors: Christopher Joseph AQUINO, Pek Yoke CHONG, Maosheng DUAN, Wieslaw Mieczyslaw KAZMIERSKI
  • Heterocyclic compounds as CCR5 antagonists
    Patent number: 7452992
    Abstract: The present invention relates to compounds of formula (I), or pharmaceutically acceptable derivatives thereof, useful in the treatment of CCR5-related diseases and disorders, for example, useful in the inhibition of HIV replication, the prevention or treatment of an HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).
    Type: Grant
    Filed: December 12, 2003
    Date of Patent: November 18, 2008
    Assignee: SmithKline Beecham Corporation
    Inventors: Christopher Joseph Aquino, Pek Yeng Chong, Maosheng Duan, Wieslaw Mieczyslaw Kazmierski
  • Pyrrolidine and azetidine compounds as CCR5 antagonists
    Patent number: 7271172
    Abstract: The present invention relates to compounds of formula (I), or pharmaceutically acceptable derivatives thereof, useful in the treatment of CCR5-related diseases and disorders, for example, useful in the inhibition of HIV replication, the prevention or treatment of an HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).
    Type: Grant
    Filed: December 12, 2003
    Date of Patent: September 18, 2007
    Assignee: SmithKline Beecham Corporation
    Inventors: Hanbiao Yang, Wieslaw Mieczyslaw Kazmierski, Christopher Joseph Aquino
  • Treatment of septic shock
    Patent number: 7022734
    Abstract: The use of transition metal complexes in the treatment of septic shock, in particular the hypotension associated therewith and pharmaceutical formulations comprising such complexes are disclosed. The use of such transition metal complexes in the treatment of other conditions caused by pathological NO production are also disclosed.
    Type: Grant
    Filed: August 6, 2002
    Date of Patent: April 4, 2006
    Assignee: Molichem Medicines, Inc.
    Inventors: Wieslaw Mieczyslaw Kazmierski, Luis Molina
  • Treatment of septic shock
    Publication number: 20030008856
    Abstract: The use of transition metal complexes in the treatment of septic shock, in particular the hypotension associated therewith and pharmaceutical formulations comprising such complexes are disclosed. The use of such transition metal complexes in the treatment of other conditions caused by pathological NO production are also disclosed.
    Type: Application
    Filed: August 6, 2002
    Publication date: January 9, 2003
    Inventors: Wieslaw Mieczyslaw Kazmierski, Luis Molina
  • Treatment of septic shock
    Patent number: 6465511
    Abstract: The use of transition metal complexes in the treatment of septic shock, in particular the hypotension associated therewith and pharmaceutical formulation comprising such complexes are disclosed. The use of such transition metal complexes in the treatment of other conditions caused by pathological NO production are also disclosed.
    Type: Grant
    Filed: August 27, 1997
    Date of Patent: October 15, 2002
    Assignee: Molichem Medicines, Inc.
    Inventors: Wieslaw Mieczyslaw Kazmierski, Luis Molina