Patents by Inventor Wilbur R. Leopold, III

Wilbur R. Leopold, III has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4853221
    Abstract: 5-Methyl-6-[[(3,4,5-trimethoxyphenyl)amino]-methyl]-2,4-quinazolinediamine (trimetrexate) has been shown to possess clinical activity against non-small cell lung cancer, head and neck squamous cancers, and breast cancer. The compound also demonstrates therapeutic synergy with several known antineoplastic agents. Methods of treating non-small cell lung cancer, head and neck cancers, and breast cancer by administering trimetrexate alone or in combination with other neoplastic agents is disclosed.
    Type: Grant
    Filed: October 23, 1987
    Date of Patent: August 1, 1989
    Assignee: Warner-Lambert Company
    Inventors: Edward F. Elslager, Wilbur R. Leopold, III