Patents by Inventor Wilford Mendelson

Wilford Mendelson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for preparing substituted 4-phenyl-4-cyanocylohexanoic acids
    Publication number: 20030083507
    Abstract: This invention relates to a method of preparing a compound type where at least one of R′ or R″ is a carbosyl group (I) by treating a compound of formula (II) with a Group I(a) or Group II(a) metal halide, with an aprotic dipolar amide-based solvent and water.
    Type: Application
    Filed: October 9, 2002
    Publication date: May 1, 2003
    Applicant: SmithKline Beecham Corporation
    Inventors: Kevin Webb, Wilford Mendelson, Jianhao Chen
  • Method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids
    Patent number: 6452022
    Abstract: This invention relates to a method of preparing a compound type where at least one of R′ or R″ is a carboxyl group (I) by treating a compound of formula (II) with a Group I(a) or Group II(a) metal halide, with an aprotic dipolar amide-based solvent and water.
    Type: Grant
    Filed: November 8, 2001
    Date of Patent: September 17, 2002
    Assignee: SmithKline Beecham Corporation
    Inventors: Kevin Webb, Wilford Mendelson, Jianhao Chen
  • METHOD FOR PREPARING SUBSTITUTED 4-PHENYL-4-CYANOCYCLOHEXANOIC ACIDS
    Publication number: 20020082440
    Abstract: This invention relates to a method of preparing a compound type where at least one of R′ or R″ is a carboxyl group (I) by treating a compound of formula (II) with a Group I(a) or Group II(a) metal halide, with an aprotic dipolar amide-based solvent and water.
    Type: Application
    Filed: November 8, 2001
    Publication date: June 27, 2002
    Applicant: SmithKline Beecham Corporation
    Inventors: Kevin Webb, Wilford Mendelson, Jianhao Chen
  • Compounds and method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids
    Patent number: 6337408
    Abstract: This invention relates to a method of preparing a compound of the following type by treating a compound of formula (II) with lithium bromide, magnesium bromide and the like.
    Type: Grant
    Filed: March 22, 2000
    Date of Patent: January 8, 2002
    Assignee: SmithKline Beecham Corporation
    Inventors: Andrew Allen, Ann Marie Diederich, Li Liu, Wilford Mendelson, Kevin Webb
  • Large scale preparation of 2,4-dihydroxybenzaldehyde using a variation of the Vilsmeierhaack reaction and isolated intermediates
    Patent number: 5599988
    Abstract: A novel process for producing chiral hydroxylamines for use as intermediates to make chiral hydroxyureas, which process comprises a tandem condensation-cyclization reaction between a dimethylsulfoxoniurn methylide and an appropriately substituted nitrone bearing a D- or L- mannose chiral auxiliary to yield a compound of Formula (I) as claimed herein.
    Type: Grant
    Filed: December 22, 1994
    Date of Patent: February 4, 1997
    Assignee: SmithKline Beecham Corporation
    Inventor: Wilford Mendelson