Patents by Inventor Wilfred F. Ngwa

Wilfred F. Ngwa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230111402
    Abstract: Methods and systems for radiation therapy involve administering a payload / combination of biocompatible high-Z and semiconductor NPs to tissue, such as a tumor or an eye. Ionizing radiation may be directed towards the payload, and ionized electrons generate Cerenkov radiation (CR). The CR interacts with semiconductor NPs to produce chemical species that are damaging to cells. The payload may be administered via injection or via a radiotherapy (RT) device that includes NPs in a biodegradable polymer matrix. Biodegradation of the polymer matrix, which results in release of its payload, may be remotely activated using, for example, electromagnetic or sound waves. The payload may include one or more immunologic adjuvants capable of promoting an immunologic response at remote sites (such as a metastatic tumors) that are separate from the site at which the NPs and adjuvants were administered.
    Type: Application
    Filed: May 9, 2022
    Publication date: April 13, 2023
    Inventor: Wilfred F. Ngwa
  • Patent number: 11534471
    Abstract: The present disclosure relates to the isolation, preservation, compositions and uses of extracts from a newly discovered species of Justicia plants. The present disclosure also relates to compositions comprising the extracts of the new species of Justicia plant, as well as methods of producing and using such compositions for treating blood disorders and/or for other health, food and industrial uses.
    Type: Grant
    Filed: September 21, 2018
    Date of Patent: December 27, 2022
    Assignees: DANA-FARBER CANCER INSTITUTE, INC., THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
    Inventor: Wilfred F. Ngwa
  • Patent number: 11351258
    Abstract: Methods and systems for radiation therapy involve administering a payload/combination of biocompatible high-Z and semiconductor NPs to tissue, such as a tumor or an eye. Ionizing radiation may be directed towards the payload, and ionized electrons generate Cerenkov radiation (CR). The CR interacts with semiconductor NPs to produce chemical species that are damaging to cells. The payload may be administered via injection or via a radiotherapy (RT) device that includes NPs in a biodegradable polymer matrix. Biodegradation of the polymer matrix, which results in release of its payload, may be remotely activated using, for example, electromagnetic or sound waves. The payload may include one or more immunologic adjuvants capable of promoting an immunologic response at remote sites (such as a metastatic tumors) that are separate from the site at which the NPs and adjuvants were administered.
    Type: Grant
    Filed: April 3, 2017
    Date of Patent: June 7, 2022
    Assignee: The Brigham and Women's Hospital, Inc
    Inventor: Wilfred F. Ngwa
  • Publication number: 20200289596
    Abstract: The present disclosure relates to the isolation, preservation, compositions and uses of extracts from a newly discovered species of Justicia plants. The present disclosure also relates to compositions comprising the extracts of the new species of Justicia plant, as well as methods of producing and using such compositions for treating blood disorders and/or for other health, food and industrial uses.
    Type: Application
    Filed: September 21, 2018
    Publication date: September 17, 2020
    Inventor: Wilfred F. NGWA
  • Publication number: 20200253143
    Abstract: A new species of Justicia plants preliminarily named Justicia sanguinis is disclosed. The present disclosure relates to the morphological and physiological characteristics of the newly discovered Justicia plants and their uses. The disclosure further relates to methods of making and drinking a beverage produced using a Justicia plant of the present invention or a part thereof.
    Type: Application
    Filed: September 21, 2018
    Publication date: August 13, 2020
    Inventor: Wilfred F. NGWA
  • Publication number: 20190111134
    Abstract: Methods and systems for radiation therapy involve administering a payload/combination of biocompatible high-Z and semiconductor NPs to tissue, such as a tumor or an eye. Ionizing radiation may be directed towards the payload, and ionized electrons generate Cerenkov radiation (CR). The CR interacts with semiconductor NPs to produce chemical species that are damaging to cells. The payload may be administered via injection or via a radiotherapy (RT) device that includes NPs in a biodegradable polymer matrix. Biodegradation of the polymer matrix, which results in release of its payload, may be remotely activated using, for example, electromagnetic or sound waves. The payload may include one or more immunologic adjuvants capable of promoting an immunologic response at remote sites (such as a metastatic tumors) that are separate from the site at which the NPs and adjuvants were administered.
    Type: Application
    Filed: April 3, 2017
    Publication date: April 18, 2019
    Inventor: Wilfred F. Ngwa