Patents by Inventor Wilfred H. Nelson

Wilfred H. Nelson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Direct detection of bacteria-antibody complexes via UV resonance Raman spectroscopy
    Patent number: 6844199
    Abstract: A system for the detection of bacteria based on bacteria-antibody complexes. Bacteria attached to antibody are detected with resonance Raman spectroscopy. The bacteria are detected directly in a great numerical excess, e.g. 100 to 10,000 of antibody molecules. A sample to be tested is placed in a medium, the medium containing antibodies attached to a surface for binding to a specific bacteria to form an antigen to antibody complex. The medium is contacted with a beam of light energy. The bacteria, as a lower resonance enhanced Raman backscattered energy, is analyzed for the presence or absence of the bacteria.
    Type: Grant
    Filed: March 14, 1997
    Date of Patent: January 18, 2005
    Assignee: The Board of Governors for Higher Education, State of Rhode Island and Providence Plantations
    Inventors: Wilfred H. Nelson, Jay F. Sperry
  • Antibiotic susceptibility test
    Patent number: 5573927
    Abstract: This invention relates to a method for biodetection and identification of antibiotic susceptibility tested in bacteria by cerating spectrum against target cells and comparing them.
    Type: Grant
    Filed: November 18, 1992
    Date of Patent: November 12, 1996
    Inventor: Wilfred H. Nelson
  • Detection and indentification of bacteria by means of ultra-violet excited resonance Raman spectra
    Patent number: 4847198
    Abstract: A bacterial suspension is contacted by a single vavelength in the ultra-violet range. A portion of the light energy used is absorbed and a portion of the light energy is emitted. The emitted light energy, resonance enhanced Raman scattering, is measured as backscattered energy. The energy is processed to produce spectra which are characteristic of the bacteria.
    Type: Grant
    Filed: October 7, 1987
    Date of Patent: July 11, 1989
    Assignee: The Board of Governors for Higher Education, State of Rhode Island and Providence Plantations
    Inventors: Wilfred H. Nelson, Richard A. Dalterio, Jay F. Sperry