Patents by Inventor Wilfried Claes

Wilfried Claes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • L-amino acid-containing feedstuff additive
    Patent number: 11076616
    Abstract: By substituting biomass with a surface-active substance in a fermentation broth containing amino acid before spray-drying, granulated animal feed additives with improved product specifications were obtained.
    Type: Grant
    Filed: October 6, 2014
    Date of Patent: August 3, 2021
    Assignee: Evonik Operations GmbH
    Inventors: Ansgar Oelmann, Hans Christian Alt, Franz Ulrich Becker, Wilfried Blümke, Wilfried Claes
  • MICROORGANISM AND METHOD FOR PRODUCTION OF AMINO ACIDS BY FERMENTATION
    Publication number: 20160265072
    Abstract: The invention relates to a microorganism that produces and/or secretes an organic chemical compound, wherein the microorganism has an increased expression, compared to the respective starting strain, of a polypeptide LpdA with the activity of a transhydrogenase; and a process for producing an organic chemical compound using the microorganism according to the invention.
    Type: Application
    Filed: January 13, 2014
    Publication date: September 15, 2016
    Inventors: Frederik Walter, Marcus Persicke, Jorn Kalinowski, Andrea Huser, Wilfried Claes, Alexander Reth
  • L-AMINO ACID-CONTAINING FEEDSTUFF ADDITIVE
    Publication number: 20160255863
    Abstract: By substituting biomass with a surface-active substance in a fermentation broth containing amino acid before spray-drying, granulated animal feed additives with improved product specifications were obtained.
    Type: Application
    Filed: October 6, 2014
    Publication date: September 8, 2016
    Applicant: Evonik Degussa GmbH
    Inventors: Ansgar Oelmann, Hans Christian Alt, Franz Ulrich Becker, Wilfried Blümke, Wilfried Claes
  • Microorganism and Method for the Fermentative Production of an Organic-Chemical Compound
    Publication number: 20160244490
    Abstract: The invention relates to a microorganism which produces and/or secretes an organic-chemical compound, wherein the microorganism has increased expression, compared to the particular starting strain, of one or more protein subunits of the ABC transporter having the activity of a trehalose importer, said microorganism being capable of taking up trehalose from the medium; and to a method for the production of an organic-chemical compound, using the microorganism according to the invention, wherein accumulation of trehalose in the fermentation broth is reduced or avoided.
    Type: Application
    Filed: May 5, 2016
    Publication date: August 25, 2016
    Applicant: Evonik Degussa GmbH
    Inventors: Stephan Hans, Brigitte Bathe, Alexander Reth, Wilfried Claes, Reinhard Krämer, Gerd Seibold, Alexander Henrich
  • Microorganism and method for the fermentative production of an organic-chemical compound
    Patent number: 9359413
    Abstract: The invention relates to a microorganism which produces and/or secretes an organic-chemical compound, wherein the microorganism has increased expression, compared to the particular starting strain, of one or more protein subunits of the ABC transporter having the activity of a trehalose importer, said microorganism being capable of taking up trehalose from the medium; and to a method for the production of an organic-chemical compound, using the microorganism according to the invention, wherein accumulation of trehalose in the fermentation broth is reduced or avoided.
    Type: Grant
    Filed: April 3, 2012
    Date of Patent: June 7, 2016
    Assignee: Evonik Degussa GmbH
    Inventors: Stephan Hans, Brigitte Bathe, Alexander Reth, Wilfried Claes, Reinhard Krämer, Gerd Seibold, Alexander Henrich
  • MICROORGANISM AND METHOD FOR PRODUCTION OF AMINO ACIDS BY FERMENTATION
    Publication number: 20160053335
    Abstract: The invention relates to a microorganism that produces and/or secretes an organic chemical compound, wherein the microorganism has an increased expression, compared to the respective starting strain, of a polypeptide LpdA with the activity of a transhydrogenase; and a process for producing an organic chemical compound using the microorganism according to the invention.
    Type: Application
    Filed: January 13, 2014
    Publication date: February 25, 2016
    Inventors: Frederik Walter, Marcus Persicke, Jörn Kalinowski, Andrea Hüser, Wilfried Claes, Alexander Reth
  • Method for fermentatively preparing L-amino acids
    Patent number: 9163268
    Abstract: The invention relates to a method for preparing organic-chemical compounds, characterized in that the following steps are carried out: a) fermentation of a microorganism secreting an L-amino acid, which microorganism contains an overexpressed polynucleotide coding for a polypeptide having polyphosphate-dependent NAD+ kinase activity, in a fermentation medium, to form a fermentation broth, b) accumulation of said compound in said fermentation broth and/or in the cells of said microorganism. The invention relates to a method for preparing organic-chemical compounds by fermentation of a microorganism in which a polypeptide having polyphosphate-dependent NAD+ kinase is overexpressed.
    Type: Grant
    Filed: June 18, 2010
    Date of Patent: October 20, 2015
    Assignee: Evonik Degussa GmbH
    Inventors: Volker F. Wendisch, Steffen Lindner, Brigitte Bathe, Wilfried Claes
  • Variants of the promoter of the gap gene coding for glyceraldehyde-3-phosphate dehydrogenase
    Patent number: 9074229
    Abstract: The invention relates to an isolated polynucleotide having promoter activity, a variant of the promoter of the gap gene coding for glyceraldehyde-3-phosphate dehydrogenase; and to a microorganism which produces and/or secretes a fine chemical, the microorganism including the isolated polynucleotide having promoter activity, which enables various genes to be overexpressed in comparison with the particular starting strain; and to a process for preparing fine chemicals using the microorganism.
    Type: Grant
    Filed: January 28, 2015
    Date of Patent: July 7, 2015
    Assignee: EVONIK DEGUSSA GmbH
    Inventors: Alexander Reth, Brigitte Bathe, Stephan Hans, Wilfried Claes
  • Variants of the promoter of the gap gene coding for glyceraldehyde-3-phosphate dehydrogenase
    Patent number: 9045762
    Abstract: The invention relates to an isolated polynucleotide having promoter activity, a variant of the promoter of the gap gene coding for glyceraldehyde-3-phosphate dehydrogenase; and to a microorganism which produces and/or secretes a fine chemical, the microorganism including the isolated polynucleotide having promoter activity, which enables various genes to be overexpressed in comparison with the particular starting strain; and to a process for preparing fine chemicals using the microorganism.
    Type: Grant
    Filed: November 4, 2014
    Date of Patent: June 2, 2015
    Assignee: EVONIK DEGUSSA GmbH
    Inventors: Alexander Reth, Brigitte Bathe, Stephan Hans, Wilfried Claes
  • VARIANTS OF THE PROMOTER OF THE GAP GENE CODING FOR GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE
    Publication number: 20150140614
    Abstract: The invention relates to an isolated polynucleotide having promoter activity, a variant of the promoter of the gap gene coding for glyceraldehyde-3-phosphate dehydrogenase; and to a microorganism which produces and/or secretes a fine chemical, the microorganism including the isolated polynucleotide having promoter activity, which enables various genes to be overexpressed in comparison with the particular starting strain; and to a process for preparing fine chemicals using the microorganism.
    Type: Application
    Filed: January 28, 2015
    Publication date: May 21, 2015
    Applicant: EVONIK DEGUSSA GMBH
    Inventors: ALEXANDER RETH, BRIGITTE BATHE, STEPHAN HANS, WILFRIED CLAES
  • VARIANTS OF THE PROMOTER OF THE GAP GENE CODING FOR GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE
    Publication number: 20150056666
    Abstract: The invention relates to an isolated polynucleotide having promoter activity, a variant of the promoter of the gap gene coding for glyceraldehyde-3-phosphate dehydrogenase; and to a microorganism which produces and/or secretes a fine chemical, the microorganism including the isolated polynucleotide having promoter activity, which enables various genes to be overexpressed in comparison with the particular starting strain; and to a process for preparing fine chemicals using the microorganism.
    Type: Application
    Filed: November 4, 2014
    Publication date: February 26, 2015
    Applicant: Evonik Degussa GmbH
    Inventors: Alexander RETH, Brigitte Bathe, Stephan Hans, Wilfried Claes
  • Process for the fermentative preparation of L-ornithine
    Patent number: 8951759
    Abstract: A process for the fermentative preparation of L-ornithine using microorganisms characterized by an increased export of the amino acid.
    Type: Grant
    Filed: February 20, 2014
    Date of Patent: February 10, 2015
    Assignee: Evonik Degussa GmbH
    Inventors: Wilfried Claes, Robert Gerstmeir
  • Variants of the promoter of the gap gene coding for glyceraldehyde-3-phosphate dehydrogenase
    Patent number: 8912313
    Abstract: The invention relates to an isolated polynucleotide having promoter activity, a variant of the promoter of the gap gene coding for glyceraldehyde-3-phosphate dehydrogenase; and to a microorganism which produces and/or secretes a fine chemical, the microorganism including the isolated polynucleotide having promoter activity, which enables various genes to be overexpressed in comparison with the particular starting strain; and to a process for preparing fine chemicals using the microorganism.
    Type: Grant
    Filed: June 27, 2012
    Date of Patent: December 16, 2014
    Assignee: Evonik Degussa GmbH
    Inventors: Alexander Reth, Brigitte Bathe, Stephan Hans, Wilfried Claes
  • PROCESS FOR THE FERMENTATIVE PREPARATION OF L-ORNITHINE
    Publication number: 20140206068
    Abstract: A process for the fermentative preparation of L-ornithine using microorganisms characterized by an increased export of the amino acid.
    Type: Application
    Filed: February 20, 2014
    Publication date: July 24, 2014
    Applicant: Evonik Degussa GmbH
    Inventors: Wilfried CLAES, Robert Gerstmeir
  • Process for the fermentative preparation of L-ornithine
    Patent number: 8741608
    Abstract: A process for the fermentative preparation of L-ornithine using microorganisms characterized by an increased export of the amino acid.
    Type: Grant
    Filed: March 29, 2011
    Date of Patent: June 3, 2014
    Assignee: Evonik Degussa GmbH
    Inventors: Wilfried Claes, Robert Gerstmeir
  • Process for the production of L-lysine
    Patent number: 8637295
    Abstract: The invention relates to mutants of coryneform bacteria in which genes have been enhanced by the use of a mutated promoter region, and to processes for the production of amino acids using bacteria according to the invention.
    Type: Grant
    Filed: December 7, 2011
    Date of Patent: January 28, 2014
    Assignee: Evonik Degussa GmbH
    Inventors: Wilfried Claes, Brigitte Bathe
  • Alleles of the oxyR gene from coryneform bacteria
    Patent number: 8592187
    Abstract: The invention relates to mutants and alleles of the oxyR gene of coryneform bacteria coding for variants of the OxyR transcription regulator and processes for producing amino acids using bacteria which comprise these alleles.
    Type: Grant
    Filed: February 15, 2011
    Date of Patent: November 26, 2013
    Assignee: Evonik Degussa GmbH
    Inventors: Brigitte Bathe, Wilfried Claes, Silke Jerrentrup, Caroline Kreutzer, Georg Thierbach
  • Alleles of the oxyR Gene from Coryneform Bacteria
    Publication number: 20130142937
    Abstract: The invention relates to mutants and alleles of the oxyR gene of coryneform bacteria coding for variants of the OxyR transcription regulator and processes for producing amino acids using bacteria which comprise these alleles.
    Type: Application
    Filed: February 15, 2011
    Publication date: June 6, 2013
    Inventors: Brigitte Bathe, Wilfried Claes, Silke Jerrentrup, Caroline Kreutzer, Georg Thierbach
  • VARIANTS OF THE PROMOTER OF THE GAP GENE CODING FOR GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE
    Publication number: 20130004999
    Abstract: The invention relates to an isolated polynucleotide having promoter activity, a variant of the promoter of the gap gene coding for glyceraldehyde-3-phosphate dehydrogenase; and to a microorganism which produces and/or secretes a fine chemical, the microorganism including the isolated polynucleotide having promoter activity, which enables various genes to be overexpressed in comparison with the particular starting strain; and to a process for preparing fine chemicals using the microorganism.
    Type: Application
    Filed: June 27, 2012
    Publication date: January 3, 2013
    Applicant: Evonik Degussa GmbH
    Inventors: Alexander RETH, Brigitte Bathe, Stephan Hans, Wilfried Claes
  • Microorganism and Method for the Fermentative Production of an Organic-Chemical Compound
    Publication number: 20120252075
    Abstract: The invention relates to a microorganism which produces and/or secretes an organic-chemical compound, wherein the microorganism has increased expression, compared to the particular starting strain, of one or more protein subunits of the ABC transporter having the activity of a trehalose importer, said microorganism being capable of taking up trehalose from the medium; and to a method for the production of an organic-chemical compound, using the microorganism according to the invention, wherein accumulation of trehalose in the fermentation broth is reduced or avoided.
    Type: Application
    Filed: April 3, 2012
    Publication date: October 4, 2012
    Applicant: Evonik Degussa GmbH
    Inventors: Stephan Hans, Brigitte Bathe, Alexander Reth, Wilfried Claes, Reinhard Krämer, Gerd Seibold, Alexander Henrich