Patent number: 7244846
Abstract: Compounds of the formula (I), in which D, R1, R2 and n are defined in Claim 1, are potent 5-HT1A agonists and 5-HT reuptake inhibitors and are suitable for the treatment of depression, anxiety states, panic attacks, obsessive-compulsive disorders, psychiatric illnesses, cerebral infarction, cerebral ischaemia, tension states, side-effects in the treatment of high blood pressure, for the prophylaxis and therapy of cerebral illnesses, acromegaly, hypogonadism, secondary amenorrhoea, premenstrual syndrome, undesired puerperal lactation, pain, sleep disorders, narcolepsy, bipolar illnesses, mania, dementia, addiction illnesses, sexual dysfunction, eating disorders, obesity or fibromyalgia
Type:
Grant
Filed:
February 27, 2002
Date of Patent:
July 17, 2007
Assignee:
Merck Patent GmbH
Inventors:
Dieter Dorsch, Henning Boettcher, Christoph van Amsterdam, Wilfried Rautenberg, Gerd Bartoszyk