Patents by Inventor Wilfried Schrock
Wilfried Schrock has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 3978223Abstract: 6-(.alpha.-3-Acyl-ureidoacetamido)-penicillanic acids and pharmaceutically acceptable non-toxic salts thereof in which the hydrogen atom of the nitrogen atom present in the 3-position is substituted, are effective against Gram-positive and Gram-negative infections, particularly Klebsiella aerobacter infections.Type: GrantFiled: April 16, 1975Date of Patent: August 31, 1976Assignee: Bayer AktiengesellschaftInventors: Hans-Bodo Konig, Wilfried Schrock, Hans Disselnkotter, Karl Georg Metzer
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Patent number: 3978056Abstract: Arylmethyl- and cyclohexenylmethyl- penicillins, substituted on the .alpha.-carbon atom of the side chain by a 2,3-disubstituted imidazolidinylcarbamide or a 2,3-disubstituted imidazolidinylthiocarbamido group, or by the corresponding 2,3-disubstituted 1,3-diazacyclohexylcarbamido or thiocarbamido groups are anti-bacterial agents.Type: GrantFiled: September 3, 1974Date of Patent: August 31, 1976Assignee: Bayer AktiengesellschaftInventors: Hans-Bodo Konig, Wilfried Schrock, Karl-Georg Metzger
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Patent number: 3975375Abstract: Arylmethyl- and cyclohexenylmethyl- penicillins, substituted on the .alpha.-carbon atom of the side chain by a 2,3-disubstituted imidazolidinylcarbamide or a 2,3-disubstituted imidazolidinylthiocarbamido group, or by the corresponding 2,3-disubstituted 1,3-diazacyclohexylcarbamido or thiocarbamido groups are anti-bacterial agents.Type: GrantFiled: September 3, 1974Date of Patent: August 17, 1976Assignee: Bayer AktiengesellschaftInventors: Hans-Bodo Konig, Wilfried Schrock, Karl-Georg Metzger
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Patent number: 3974140Abstract: 6-(.alpha.-3-Acyl-ureidoacetamido)-penicillanic acids and pharmaceutically acceptable non-toxic salts thereof in which the hydrogen atom of the nitrogen atom present in the 3-position is substituted, are effective against Gram-positive and Gram-negative infections, particularly Klebsiella aerobacter infections.Type: GrantFiled: August 13, 1975Date of Patent: August 10, 1976Assignee: Bayer AktiengesellschaftInventors: Hans-Bodo Konig, Wilfried Schrock, Hans Disselnkotter, Karl Georg Metzer
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Patent number: 3974141Abstract: Arylmethyl- and cyclohexenylmethyl- penicillins, substituted on the .alpha.carbon atom of the side chain by a 2,3-disubstituted imidazolidinylcarbamido or a 2,3-disubstituted imidazolidinylthiocarbamido group, or by the corresponding 2,3-disubstituted 1,3-diazacyclohexylcarbamido or thiocarbamido groups are anti-bacterial agents.Type: GrantFiled: September 3, 1974Date of Patent: August 10, 1976Assignee: Bayer AktiengesellschaftInventors: Hans-Bodo Konig, Wilfried Schrock, Karl-Georg Metzger
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Patent number: 3974142Abstract: Arylmethyl- and cyclohexenylmethyl- penicillins, substituted on the .alpha.carbon atom of the side chain by a 2,3-disubstituted imidazolidinylcarbamido or a 2,3-disubstituted imidazolidinylthiocarbamido group, or by the corresponding 2,3-disubstituted 1,3-diazacyclohexylcarbamido or thiocarbamido groups are anti-bacterial agents.Type: GrantFiled: September 3, 1974Date of Patent: August 10, 1976Assignee: Bayer AktiengesellschaftInventors: Hans-Bodo Konig, Wilfried Schrock, Karl-Georg Metzger
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Patent number: 3974288Abstract: A compound of the formula: ##SPC1##Or a pharmaceutically acceptable nontoxic salt thereof whereinR.sub.1 is hydrogen, straight or branched chain alkyl of 1 to 5 carbon atoms, monoaralkyl of up to 8 carbon atoms, monoaryl, substituted monoaryl, or thienyl;A is moiety of the formula: ##EQU1## wherein R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6 and R.sub.7 are the same or different and each is hydrogen, straight or branched chain alkyl of 1 to 5 carbon atoms, monoaralkyl of up to 8 carbon atoms, monoaryl, substituted monoaryl, or thienyl;B is a moiety of the formula: ##SPC2##WhereinR.sub.8, r.sub.9 and R.sub.10 are the same or different and each is hydrogen, fluorine, chlorine, bromine.Type: GrantFiled: January 28, 1975Date of Patent: August 10, 1976Assignee: Bayer AktiengesellschaftInventors: Wilfried Schrock, Karl-Georg Metzger, Hans-Bodo Konig
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Patent number: 3972869Abstract: Penicillins of the formula ##EQU1## or pharmaceutically acceptable non-toxic salts thereof, wherein C is a carbon atom constituting a center of chirality;A is a moiety of the formula ##EQU2## or ##EQU3## wherein X is ##EQU4## Y is ##EQU5## or wherein Aryl is an aryl moiety; Z is ##EQU6## Q.sub.1 is ##EQU7## or ##SPC1##Q.sub.2 is ##EQU8## ##SPC2##or ##SPC3##R is straight-chain or branched alkyl of 1 to 5 carbon atoms;R.sub.1 is alkyl of 1 to 10 carbon atoms, cycloalkyl of 3 to 10 carbon atoms, alkenyl of 2 to 10 carbon atoms, cycloalkenyl of 3 to 10 carbon atoms, vinyl, arylvinyl, mono-, di-, or tri-halo-lower alkyl, H.sub.2 N--, R--NH--, (R).sub.2 N--, aryl--NH--, aryl-lower alkylamino, alkoxy of 1 to 8 carbon atoms, aralkoxy of 1 to 8 carbon atoms in the alkoxy portion, cycloalkoxy of 3 to 7 carbon atoms, aryloxy, R--O--V--, R--S-- V--, N=C--V--, R--O--CO--V--, H.sub.2 N--CO--V--, R--NH--CO--V--, R--O--CO--NH--, R--SO.sub.2 --NH--, (R).sub.Type: GrantFiled: September 3, 1974Date of Patent: August 3, 1976Assignee: Bayer AktiengesellschaftInventors: Hans-Bodo Konig, Wilfried Schrock, Karl-Georg Metzger
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Patent number: 3972870Abstract: Penicillins of the formula ##EQU1## or pharmaceutically acceptable non-toxic salts thereof, wherein C* is a carbon atom constituting a center of chirality;A is a moiety of the formula ##EQU2## or ##EQU3## wherein X is ##EQU4## Y is ##EQU5## or wherein Aryl is an aryl moiety; Z is ##EQU6## Q.sub.1 is ##EQU7## or ##SPC1##Q.sub.2 is ##EQU8## ##SPC2##or ##SPC3##R is straight- chain or branched alkyl of 1 to 5 carbon atoms;R.sub.1 is alkyl of 1 to 10 carbon atoms, cycloalkyl of 3 to 10 carbon atoms, alkenyl of 2 to 10 carbon atoms, cycloalkenyl of 3 to 10 carbon atoms. vinyl, arylvinyl, mono-, di-, or tri-halo-lower alkyl, H.sub.2 N--, R--NH--, (R).sub.2 N--, aryl--NH--, aryl-lower alkylamino, alkoxy of 1 to 8 carbon atoms, aralkoxy of 1 to 8 carbon atoms in the alkoxy portion, cycloalkoxy of 3 to 7 carbon atoms, aryloxy, R--O--V--, R--S--V--, N=C--V--, R--O--CO--V--, H.sub.2 N--CO--V--, R--NH--CO--V--, R--O--CO--NH--, R--SO.sub.2 --NH--, (R).sub.Type: GrantFiled: September 3, 1974Date of Patent: August 3, 1976Assignee: Bayer AktiengesellschaftInventors: Hans-Bodo Konig, Wilfried Schrock, Karl-Georg Metzger
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Patent number: 3966709Abstract: .beta.-Lactams of the formula ##SPC1##And pharmaceutically acceptable nontoxic salts thereof whereinA is hydrogen or alkyl of 1 to 4 carbon atoms;B is phenyl, methylphenyl, chlorophenyl, hydroxyphenyl or cyclohexa-1,4-dien-1-yl;R is a moiety of the formula ##SPC2##WhereinE is hydrogen --OH or --O-- CO--CH.sub.3 ; andC constitutes a center of chirality; are produced which exhibit antibiotic activity.Type: GrantFiled: October 25, 1974Date of Patent: June 29, 1976Assignee: Bayer AktiengesellschaftInventors: Hans-Bodo Konig, Karl Georg Metzger, Wilfried Schrock
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Patent number: 3959258Abstract: 6-(.alpha.-3-Acyl-ureidoacetamido)-penicillanic acids and pharmaceutically acceptable non-toxic salts thereof in which the hydrogen atom of the nitrogen atom present in the 3-position is substituted, are effective against Gram-positive and Gram-negative infections, particularly Klebsiella aerobacter infections.Type: GrantFiled: December 19, 1973Date of Patent: May 25, 1976Assignee: Bayer AktiengesellschaftInventors: Hans-Bodo Konig, Wilfried Schrock, Hans Disselnkotter, Karl Georg Metzger
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Patent number: 3939149Abstract: 6-(.alpha.-3-Acyl-ureidoacetamido)-penicillanic acids and pharmaceutically acceptable non-toxic salts thereof in which the hydrogen atom of the nitrogen atom present in the 3-position is substituted, are effective against Gram-positive and Gram-negative infections, particularly Klebsiella aerobacter infections.Type: GrantFiled: December 19, 1973Date of Patent: February 17, 1976Assignee: Bayer AktiengesellschaftInventors: Hans-Bodo Konig, Wilfried Schrock, Hans Disselnkotter, Karl Georg Metzger
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Patent number: 3936442Abstract: 6-(.alpha.-3-Acyl-ureidoacetamido)-penicillanic acids and pharmaceutically acceptable non-toxic salts thereof in which the hydrogen atom of the nitrogen atom present in the 3-position is substituted, are effective against Gram-positive and Gram-negative infections, particularly Klebsiella aerobacter infections.Type: GrantFiled: December 19, 1973Date of Patent: February 3, 1976Assignee: Bayer AktiengesellschaftInventors: Hans-Bodo Konig, Wilfried Schrock, Hans Disselnkotter, Karl Georg Metzer