Patents by Inventor Wilfried Schwab

Wilfried Schwab has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sulfonylaminocarboxylic acids
    Patent number: 7160903
    Abstract: Compounds of formula (I) are suitable for the production of pharmaceuticals for the prophylaxis and therapy of disorders in the course of which an increased activity of matrix-degrading metalloproteinases is involved.
    Type: Grant
    Filed: June 13, 2002
    Date of Patent: January 9, 2007
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Werner Thorwart, Wilfried Schwab, Manfred Schudok, Burkhard Haase
  • Process for preparing 2-cyano-3-hydroxy-N-(phenyl)but-2-enamides
    Patent number: 6894184
    Abstract: A process is described for producing 2-cyano-3-hydroxy-N-(phenyl)but-2-enamide, in which a phenyl-substituted 2-cyano-N-(phenyl)acetamide is reacted in the presence of a base, acetic anhydride and at least one solvent, and the resultant 2-cyano-3-hydroxy-N-(phenyl-derivative)but-2-enamide is crystallized by acidification.
    Type: Grant
    Filed: March 17, 2004
    Date of Patent: May 17, 2005
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Jochen Hachtel, Bernd Neises, Wilfried Schwab, Roland Utz, Martin Zahn
  • Cyclic and heterocyclic N-substituted &agr;-iminohydroxamic and -carboxylic acids
    Patent number: 6815440
    Abstract: Cyclic and heterocyclic N-substituted &agr;-iminohydroxamic and -carboxylic acids Compounds of the formula I are suitable for preparing pharmaceuticals for the treatment of disorders in the course of which is involved an increased activity of matrix-degrading metalloproteinases.
    Type: Grant
    Filed: March 3, 2003
    Date of Patent: November 9, 2004
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Werner Thorwart, Wilfried Schwab, Manfred Schudok, Burkhard Haase, Eckart Bartnik, Klaus-Ulrich Weithmann
  • Process for preparing 2-cyano-3-hydroxy-N-(phenyl)but-2-enamides
    Publication number: 20040186173
    Abstract: A process is described for producing 2-cyano-3-hydroxy-N-(phenyl)but-2-enamide, in which a phenyl-substituted 2-cyano-N-(phenyl)acetamide is reacted in the presence of a base, acetic anhydride and at least one solvent, and the resultant 2-cyano-3-hydroxy-N-(phenyl-derivative)but-2-enamide is crystallized by acidification.
    Type: Application
    Filed: March 17, 2004
    Publication date: September 23, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Jochen Hachtel, Bernd Neises, Wilfried Schwab, Roland Utz, Martin Zahn
  • Optically active B-aminoketones, optically active 1,3-amino alcohols and processes for preparing them
    Publication number: 20040030145
    Abstract: The invention relates to chiral Mannich bases of formula (I), chiral 1,3-amino alcohols of formula (II) derived therefrom, wherein R1, R2, R3, R4 and R5 are as defined herein, and to processes for preparing Mannich salts of formula (III) containing a chiral anion Y*− and compounds of ormulae (I) and (II), wherein R1, R2, R3, R4, R5 and Y*− are as defined herein.
    Type: Application
    Filed: May 5, 2003
    Publication date: February 12, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Heiner Jendralla, Wilfried Schwab, Thomas Stuedemann
  • Cyclic and heterocyclic N-substituted alpha-iminohydroxamic and -carboxylic acids
    Publication number: 20030176432
    Abstract: Cyclic and heterocyclic N-substituted &agr;-iminohydroxamic and -carboxylic acids
    Type: Application
    Filed: March 3, 2003
    Publication date: September 18, 2003
    Applicant: Aventis Pharma Deutschland GmbH.
    Inventors: Werner Thorwart, Wilfried Schwab, Manfred Schudok, Burkhard Haase, Eckart Bartnik, Klaus-Ulrich Weithmann
  • Cyclic and heterocyclic N-substituted &agr;-iminohydroxamic and -carboxylic acids
    Patent number: 6573277
    Abstract: Compounds of the formula I are suitable for preparing pharmaceuticals for the treatment of disorders in the course of which is involved an increased activity of matrix-degrading metalloproteinases.
    Type: Grant
    Filed: February 12, 2001
    Date of Patent: June 3, 2003
    Inventors: Werner Thorwart, Wilfried Schwab, Manfred Schudok, Burkhard Haase, Eckart Bartnik, Klaus-Ulrich Weithmann
  • Sulfonylaminocarboxylic acids
    Publication number: 20030087945
    Abstract: Compounds of formula (I) 1
    Type: Application
    Filed: June 13, 2002
    Publication date: May 8, 2003
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Werner Thorwart, Wilfried Schwab, Manfred Schudok, Burkhard Haase
  • Sulfonylaminophosphinic and sulfonylaminophosphonic acid derivatives, methods for their preparation and use
    Patent number: 6500811
    Abstract: Compounds of the formula I are suitable for the production of pharmaceuticals for the prophylaxis and therapy of disorders in the course of which an increased activity of matrix-degrading enzymes is involved.
    Type: Grant
    Filed: March 20, 2001
    Date of Patent: December 31, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Manfred Schudok, Wilfried Schwab, Gerhard Zoller, Eckart Bartnik, Frank Büttner, Klaus-Ulrich Weithmann
  • Sulfonylaminocarboxylic acids
    Patent number: 6451824
    Abstract: Compounds of formula (I) are suitable for the production of pharmaceuticals for the prophylaxis and therapy of disorders in the course of which an increased activity of matrix-degrading metalloproteinases is involved.
    Type: Grant
    Filed: May 8, 1998
    Date of Patent: September 17, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Werner Thorwart, Wilfried Schwab, Manfred Schudok, Burkhard Haase
  • Sulfonylaminophosphinic and sulfonylaminophosphonic acid derivatives, methods for their preparation and use
    Publication number: 20020082246
    Abstract: Compounds of the formula I 1
    Type: Application
    Filed: March 20, 2001
    Publication date: June 27, 2002
    Applicant: Aventis Pharma Deutschland GmbH.
    Inventors: Manfred Schudok, Wilfried Schwab, Gerhard Zoller, Eckart Bartnik, Frank Buttner, Klaus-Ulrich Weithmann
  • 2-Cyano-3,5-dihydroxyhex-2-enecarboxamide derivatives
    Patent number: 6387934
    Abstract: 2-Cyano-3,5-dihydroxyhex-2-enecarboxamide derivatives are suitable for the production of pharmaceuticals for the prophylaxis and therapy of diseases or disorders whose course involves increased connective tissue or cartilage degradation.
    Type: Grant
    Filed: October 23, 2000
    Date of Patent: May 14, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Wilfried Schwab, Ruth Raiss
  • Substituted diaminocarboxylic acids
    Patent number: 6355673
    Abstract: Compounds of formula (I) are suitable for the production of pharmaceuticals for the prophylaxis and therapy of disorders in the course of which an increased activity of matrix-degrading metalloproteinases is involved
    Type: Grant
    Filed: October 18, 2000
    Date of Patent: March 12, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Werner Thorwart, Wilfried Schwab, Manfred Schudok, Burkhard Haase, Bernhard Neises, Günter Billen
  • N-arylsulfonylamino acid omega-amides
    Patent number: 6335333
    Abstract: Compounds of the formula I: stereoisomeric forms, and physiologically tolerable salts thereof are suitable for the production of pharmaceuticals for the therapy and prophylaxis of disorders involving matrix-degrading metalloproteinases.
    Type: Grant
    Filed: December 28, 2000
    Date of Patent: January 1, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Wilfried Schwab, Werner Thorwart, Manfred Schudok, Burkhard Haase
  • Cyclic and heterocyclic N-substituted alpha-iminohydroxamic and -carboxylic acids
    Publication number: 20010011134
    Abstract: Cyclic and heterocyclic N-substituted &agr;-iminohydroxamic and -carboxylic acids
    Type: Application
    Filed: February 12, 2001
    Publication date: August 2, 2001
    Applicant: Hoechst Aktiengesellschaft
    Inventors: Werner Thorwart, Wilfried Schwab, Manfred Schudok, Burkhard Haase, Eckart Bartnik, Klaus-Ulrich Weithmann
  • Isoxazole and crotonamide derivatives and their use as pharmaceuticals and diagnostics
    Patent number: 6265588
    Abstract: A compound of the formula where R1 is the radical of the formula II or III is suitable for the production of a pharmaceutical for the treatment of inflammations, carcinomatous diseases, or autoimmune diseases. A compound of the formula IV is suitable for the production of specific antibodies against a compound of the formula I for the discovery of specific-binding proteins from cell extracts, serum, blood, or synovial fluids, for the purification of proteins, for the modification of microtiter plates, or for the preparation of chromatography material, in particular of affinity chromatography material, and for use in diagnostics.
    Type: Grant
    Filed: May 30, 2000
    Date of Patent: July 24, 2001
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Stefan Müllner, Bernd Kirschbaum, Wilfried Schwab
  • Sulfonylaminophosphinic and sulfonylaminophosphinic acid derivatives, methods for their preparation and use
    Patent number: 6235727
    Abstract: Compounds of the formula I are suitable for the production of pharmaceuticals for the prophylaxis and therapy of disorders in the course of which an increased activity of matrix-degrading enzymes is involved.
    Type: Grant
    Filed: July 15, 1999
    Date of Patent: May 22, 2001
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Manfred Schudok, Wilfried Schwab, Gerhard Zoller, Eckart Bartnik, Frank Büttner, Klaus-Ulrich Weithmann
  • Cyclic and heterocyclic N-substituted &agr;-iminohydroxamic and carboxyclic acids
    Patent number: 6207672
    Abstract: Compounds of the formula I are suitable for preparing pharmaceuticals for the treatment of disorders in the course of which is involved an increased activity of matrix-degrading metalloproteinases.
    Type: Grant
    Filed: March 9, 1999
    Date of Patent: March 27, 2001
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Werner Thorwart, Wilfried Schwab, Manfred Schudok, Burkhard Haase, Eckart Bartnik, Klaus-Ulrich Weithmann
  • N-arylsulfonylamino acid omega-amides
    Patent number: 6201130
    Abstract: Compounds of the formula I: stereoisomeric forms, and physiologically tolerable salts thereof are suitable for the production of pharmaceuticals for the therapy and prophylaxis of disorders involving matrix-degrading metalloproteinases.
    Type: Grant
    Filed: November 5, 1999
    Date of Patent: March 13, 2001
    Assignee: Aventis Pharma Duetschland GmbH
    Inventors: Wilfried Schwab, Werner Thorwart, Manfred Schudok, Burkhard Haase
  • 2-cyano-3,5-dihydroxyhex-2-enecarboxamide derivatives
    Patent number: 6172103
    Abstract: 2-Cyano-3,5-dihydroxyhex-2-enecarboxamide derivatives are suitable for the production of pharmaceuticals for the prophylaxis and therapy of diseases or disorders whose course involves increased connective tissue or cartilage degradation.
    Type: Grant
    Filed: November 24, 1999
    Date of Patent: January 9, 2001
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Wilfried Schwab, Ruth Raiss