Patents by Inventor Wilfried Seifert

Wilfried Seifert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6344323
    Abstract: The invention features antisense oligonucleotide molecules that specifically bind polynucleotides encoding COX-2. The present invention provides antisense oligonucleotides capable of inhibiting COX-2 expression, and methods of use thereof to reduce activity of COX-2 in tissues in order to treat diseases such as, for example, rheumatoid arthritis, inflammatory bowel disease, multiple sclerosis, chronic liver disease, ulcerative colitis, cell proliferative disorders, and inflammation associated with Alzheimer's Disease and stroke.
    Type: Grant
    Filed: September 16, 1999
    Date of Patent: February 5, 2002
    Assignee: Vitagenix, Inc.
    Inventor: Wilfried Seifert
  • Patent number: 5723589
    Abstract: Methods and compositions are provided which increase the cellular uptake of bioactive materials by covalently bonding such compounds to carbohydrate moieties through chemical linkers using other than glycosidic bonds. Numerous carbohydrates, linkers and bioactive materials can be joined in this way to form novel compositions, which are collectively referred to herein as glinkosides. Preferred glinkosides are preferentially taken up by glucose receptor and/or other cellular receptors, and once inside the cells, the glinkosides are cleaved into a sugar, a linker or linker fragments, and a biologically active compound. Various aspects of the invention include processes for synthesizing glinkosides, glinkoside compositions, and methods of treating diseases using glinkosides.
    Type: Grant
    Filed: December 21, 1995
    Date of Patent: March 3, 1998
    Assignee: ICN Pharmaceuticals
    Inventors: Dusan Miljkovic, Zbigniew Pietrzkowski, Esmir Gunic, Wilfried Seifert