Patents by Inventor Wilfried Wachter

Wilfried Wachter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the manufacture of flavanolignan preparation with improved release and absorbability, compositions obtainable thereby and their use for the preparation of pharmaceuticals
    Patent number: 6020384
    Abstract: The present invention provides a process for the production of a flavanolignan preparation with an improved liberation in comparison with one of the pure flavanolignans, characterised in that a) an aqueous-alcoholic solution of pharmaceutically-acceptable carrier materials and wetting agents is prepared, a flavanolignan is suspended in this solution and the mixture obtained is heated to the boiling temperature in order to form a clear solution or b) a flavanolignan and a wetting agent is suspended in alcohol, the suspension obtained is heated with stirring up to the formation of a clear solution, this is mixed with an aqueous solution of pharmaceutically-acceptable carrier materials and the mixture obtained is heated with stirring until a clear solution is present and that subsequently the clear solution obtained according to a) or b) is concentrated for the formation of a co-precipitate, filtered and the resulting co-precipitate dried in a vacuum.
    Type: Grant
    Filed: February 10, 1999
    Date of Patent: February 1, 2000
    Assignee: Madaus AG
    Inventors: Wilfried Wachter, Helga Zaeske
  • Process for the manufacture of flavanolignan preparations with improved release and absorbability, compositions obtainable thereby and their use for the preparation of pharmaceuticals
    Patent number: 5906991
    Abstract: The present invention provides a process for the production of a flavanolignan preparation with an improved liberation in comparison with one of the pure flavanolignans, characterized in that a) an aqueous-alcoholic solution of pharmaceutically-acceptable carrier materials and wetting agents is prepared, a flavanolignan is suspended in this solution and the mixture obtained is heated to the boiling temperature in order to form a clear solution or b) a flavanolignan and a wetting agent is suspended in alcohol, the suspension obtained is heated with stirring up to the formation of a clear solution, this is mixed with an aqueous solution of pharmaceutically-acceptable carrier materials and the mixture obtained is heated with stirring until a clear solution is present and that subsequently the clear solution obtained according to a) or b) is concentrated for the formation of a co-precipitate, filtered and the resulting co-precipitate dried in a vacuum.
    Type: Grant
    Filed: November 24, 1997
    Date of Patent: May 25, 1999
    Assignee: Dr. Madaus GmbH & Co
    Inventors: Wilfried Wachter, Helga Zaeske
  • Inclusion complexes with silybinin, their preparation and pharmaceutical compositions containing them
    Patent number: 5198430
    Abstract: The invention relates to inclusion complexes of Silybinin with a cyclodextrin selected from the group consisting of .alpha.-, .beta.- and .gamma.-cyclodextrin and a suitable derivative thereof and to the method for the preparation thereof. The inclusion complexes of Silybinin showed a highly improved bioavailability in comparison to Silybinin which makes them particularly interesting in the treatment of various hepatotoxic conditions.
    Type: Grant
    Filed: October 9, 1990
    Date of Patent: March 30, 1993
    Assignee: Istituto Biochimico Italiano Giovanni Lorenzini SpA
    Inventors: Umberto Valcavi, Vincenzo Monterosso, Roberto Caponi, Enrico Bosone, Wilfried Wachter, Jozsef Szejtli