Abstract: There is described an apparatus for handling and conditioning biologically injurious waste, especially radioactive waste which consists of a working space or chamber having containers for receiving and dosing the waste, conveying and control devices for the waste and the additions and a filling station for filling the final storage container. It is characterized by the working space having a slanting bottom running into a sump, the containers for receiving and dosing the waste being surrounded by a variable shielding, the cover of the final storage container provided with a stirrer convertable to the stirrer driving mechanism taking place by means of a slidable lift which supports the driving mechanism, a waste supply line, a waste air line, a positioning device and stopping pins, and controlling the sequence of operations by a freely programmable control.