Abstract: An apparatus for filling and sealing ampules has a support disc rotatable about an upright axis and provided along its outer edge with a succession of seats formed by rollers. Ampules are pressed into these seats by an endless belt spanned around the disc, or by a plurality of pressing wheels. The pressing wheels or the belt are driven so that the ampules are rotated in place in their seats during the filling and sealing operations. A tool carrier, which is pivotal about the axis of rotation of the support disc, angularly oscillates back and forth over a limited arc and the tools carried on this carrier are displaced at the same angular speed as the continuously displaced ampules so that they act on the ampules as they move in the forward direction, then return and act on the next ampule or group of ampules. These tools can be filling or sealing units.