Patents by Inventor Wilhelm Quittmann

Wilhelm Quittmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for preventing plugging of a continuous-reaction channel-system and micro-reactor for carrying out the method
    Patent number: 10058840
    Abstract: A method for preventing plugging of a continuous-reaction channel-system caused by a by-product of a continuous-reaction being carried out in said channel-system comprises the step of generating at least one ultrasonic wave travelling through said channel-system by coupling in a flow direction of at least one process fluid of a plurality of process fluids said at least one ultrasonic wave into said at least one process fluid.
    Type: Grant
    Filed: August 26, 2010
    Date of Patent: August 28, 2018
    Assignee: LONZA LTD.
    Inventors: Dominique Roberge, Fabio Rainone, Wilhelm Quittmann, Michael Gottsponer, Markus Eyholzer
  • Method for Preventing Plugging of a Continuous-Reaction Channel-System and Micro-Reactor for Carrying Out the Method
    Publication number: 20150158007
    Abstract: A method for preventing plugging of a continuous-reaction channel-system caused by a by-product of a continuous-reaction being carried out in said channel-system comprises the step of generating at least one ultrasonic wave travelling through said channel-system by coupling in a flow direction of at least one process fluid of a plurality of process fluids said at least one ultrasonic wave into said at least one process fluid.
    Type: Application
    Filed: August 26, 2010
    Publication date: June 11, 2015
    Inventors: Dominique Roberge, Fabio Rainone, Wilhelm Quittmann, Michael Gottsponer, Markus Eyholzer
  • Process for the production of carnitine by cycloaddition
    Patent number: 8563752
    Abstract: The invention relates to a method for the production of L-carnitine, wherein a chiral ?-lactone carnitine precursor is obtained by a [2+2] cycloaddition of ketene with an aldehyde X—CH2—CHO, wherein X is selected from Cl, Br, I and trimethylamine, in the presence of a chiral catalyst.
    Type: Grant
    Filed: July 20, 2011
    Date of Patent: October 22, 2013
    Assignee: Lonza Ltd.
    Inventors: Paul Hanselmann, Ellen Klegraf, Stephan Elzner, Wilhelm Quittmann, Daniel Friedrich Fischer
  • Method for lithium exchange reactions
    Patent number: 8198487
    Abstract: The present invention relates to a process for lithium exchange reactions comprising mixing at least two fluids in a microreactor having at least two injection points.
    Type: Grant
    Filed: February 1, 2008
    Date of Patent: June 12, 2012
    Assignee: Lonza AG
    Inventors: Dominique Roberge, Wilhelm Quittmann, Markus Eyholzer, Bertin Zimmermann, Fabio Rainone
  • REDUCTION OF 5-(ARYL-DIAZENYL)-4,6-DIHALO-PYRIMIDINE
    Publication number: 20120130058
    Abstract: Method of synthesizing a compound of formula (I), wherein R1, R2 are, independently, chloro or fluoro, and wherein R3 is H, alkyl, aralkyl or is an alkylether or alkylthioether comprising the steps of firstly reducing a diazeny compound of formula (II) non-catalytically or with a catalytic amount of an homogenous organic, non-metal catalyst to the corresponding hydrazo compound of formula (III) and in a second step catalytically hydrogenating said hydrazo compound in with a heterogeneous Ni-catalyst to the compound of formula (I).
    Type: Application
    Filed: January 5, 2012
    Publication date: May 24, 2012
    Inventors: Wilhelm Quittmann, Wei Zhu, Feng Ye, Rongmin Chen
  • Reduction of 5-(aryl-diazenyl)-4,6-dihalo-pyrimidine
    Patent number: 8114996
    Abstract: Method of synthesizing a compound of formula (I), wherein R1, R2 are, independently, chloro or fluoro, and wherein R3 is H, alkyl, aralkyl or is an alkylether or alkylthioether comprising the steps of firstly reducing a diazeny compound of formula (II) non-catalytically or with a catalytic amount of an homogenous organic, non-metal catalyst to the corresponding hydrazo compound of formula (III) and in a second step catalytically hydrogenating said hydrazo compound in with a heterogeneous Ni-catalyst to the compound of formula (I).
    Type: Grant
    Filed: September 28, 2010
    Date of Patent: February 14, 2012
    Assignee: Lonza AG
    Inventors: Wilhelm Quittmann, Wei Zhu, Feng Ye, Rongmin Chen
  • PROCESS FOR THE PRODUCTION OF CARNITINE BY CYCLOADDITION
    Publication number: 20120022275
    Abstract: The invention relates to a method for the production of L-carnitine, wherein a chiral ?-lactone carnitine precursor is obtained by a [2+2] cycloaddition of ketene with an aldehyde X—CH2—CHO, wherein X is selected from Cl, Br, I and trimethylamine, in the presence of a chiral catalyst.
    Type: Application
    Filed: July 20, 2011
    Publication date: January 26, 2012
    Inventors: Paul Hanselmann, Ellen Klegraf, Stephan Elzner, Wilhelm Quittmann, Daniel Friedrich Fischer
  • REDUCTION OF 5-(ARYL-DIAZENYL)-4,6-DIHALO-PYRIMIDINE
    Publication number: 20110178298
    Abstract: Method of synthesizing a compound of formula (I), wherein R1, R2 are, independently, chloro or fluoro, and wherein R3 is H, alkyl, aralkyl or is an alkylether or alkylthioether comprising the steps of firstly reducing a diazeny compound of formula (II) non-catalytically or with a catalytic amount of an homogenous organic, non-metal catalyst to the corresponding hydrazo compound of formula (III) and in a second step catalytically hydrogenating said hydrazo compound in with a heterogeneous Ni-catalyst to the compound of formula (I).
    Type: Application
    Filed: February 13, 2007
    Publication date: July 21, 2011
    Inventors: Wilhelm Quittmann, Wei Zhu, Feng Ye, Rongmin Chen
  • METHOD FOR THE PREPARATION OF ORGANIC NITRATES
    Publication number: 20100312003
    Abstract: The present invention relates to a process for the preparation of organic nitrates having at least one nitryloxy and at least one hydroxy group, wherein the at least one hydroxy group may be present in form of an esterified hydroxy residue, the latter being esterified with an acid other than nitric acid.
    Type: Application
    Filed: October 10, 2008
    Publication date: December 9, 2010
    Inventors: Walter Brieden, Dominique Michel, Wilhelm Quittmann, Fabio Rainone, Jie-Hui Pan, Hang-Bing Fang, Ying-Xia Song
  • METHOD FOR LITHIUM EXCHANGE REACTIONS
    Publication number: 20100113839
    Abstract: The present invention relates to a process for lithium exchange reactions comprising mixing at least two fluids in a microreactor having at least two injection points.
    Type: Application
    Filed: February 1, 2008
    Publication date: May 6, 2010
    Inventors: Dominique Roberge, Wilhelm Quittmann, Markus Eyholzer, Bertin Zimmermann, Fabio Rainone
  • Process for preparing .gamma.-mercaptocarboxylic acid derivatives
    Patent number: 5534651
    Abstract: .gamma.-Mercaptocarboxylic acids and their derivatives, in particular esters and amides, are prepared from .gamma.-butyrolactones via the corresponding thiolactones. The thiolactones are obtained by reaction of a .gamma.-lactone with thiocarboxylates in polar solvents and are converted by ring opening using nucleophilic reagents, such as, alkali metal alkoxides, into the .gamma.-mercaptocarboxylic acid derivatives. These are intermediates, for example, for the synthesis of leucotriene antagonists.
    Type: Grant
    Filed: August 30, 1994
    Date of Patent: July 9, 1996
    Assignee: Lonza Ltd.
    Inventors: Wilhelm Quittmann, John McGarrity
  • Process for the production of 3-aminocrotononitrile
    Patent number: 5187297
    Abstract: A process for the production of 3-aminocrotononitrile by dimerization of acetonitrile. In this process, the deprotonation step takes place with sodium amide as a strong base in the presence of liquid ammonia. 3-Aminocrotononitrile is used as an initial product for the production of pharmaceutical agents, pesticides or azo dyes.
    Type: Grant
    Filed: November 1, 1991
    Date of Patent: February 16, 1993
    Assignee: Lonza Ltd.
    Inventors: Wilhelm Quittmann, Leo Zumoberhaus, Peter Ruppen
  • Process for the purification of adenine
    Patent number: 5089618
    Abstract: Crude adenine, that is contaminated by 9-phenyladenine and/or colored additives, is converted with hexamethyldisilazane in the presence of a catalyst into N,N'-bis(trimethylsilyl) adenine, which is distilled and then reconverted into pure adenine by hydrolysis.
    Type: Grant
    Filed: July 31, 1990
    Date of Patent: February 18, 1992
    Assignee: Lonza Ltd.
    Inventor: Wilhelm Quittmann
  • Process for the reduction of the polymer portion in the dimerization of ketene
    Patent number: 4999438
    Abstract: The polymer portion in the production of diketene by the dimerization of ketene obtained from acetic acid by pyrolysis is reduced by the addition of sulfur dioxide to the ketene gas or to the reaction medium.
    Type: Grant
    Filed: January 3, 1990
    Date of Patent: March 12, 1991
    Assignee: Lonza Ltd.
    Inventors: Renzo Bergmin, Wilhelm Quittmann, Josef Stoffel
  • Process for the reduction of the ketene trimer content in raw diketene
    Patent number: 4808735
    Abstract: Process for the reduction of the ketene trimer portion in raw diketene by mixing of the diketene with water, an alcohol, a phenol or a carboxylic acid, and heating the mixture to 50.degree. to 130.degree. C., and then distilling off the diketene.
    Type: Grant
    Filed: April 5, 1988
    Date of Patent: February 28, 1989
    Assignee: Lonza Ltd.
    Inventors: Renzo Bergamin, Wilhelm Quittmann