Abstract: The present invention relates compositions and methods for microRNA (miRNA) expression profiling of colorectal cancer. In particular, the invention relates to a diagnostic kit of molecular markers for identifying one or more mammalian target cells exhibiting or having a predisposition to develop colorectal cancer, the kit comprising a plurality of nucleic acid molecules, each nucleic acid molecule encoding a miRNA sequence, wherein one or more of the plurality of nucleic acid molecules are differentially expressed in the target cells and in one or more control cells, and wherein the one or more differentially expressed nucleic acid molecules together represent a nucleic acid expression signature that is indicative for the presence of or the predisposition to develop colorectal cancer.

Abstract: The present invention relates compositions and methods for microRNA (miRNA) expression profiling of colorectal cancer. In particular, the invention relates to a diagnostic kit of molecular markers for identifying one or more mammalian target cells exhibiting or having a predisposition to develop colorectal cancer, the kit comprising a plurality of nucleic acid molecules, each nucleic acid molecule encoding a miRNA sequence, wherein one or more of the plurality of nucleic acid molecules are differentially expressed in the target cells and in one or more control cells, and wherein the one or more differentially expressed nucleic acid molecules together represent a nucleic acid expression signature that is indicative for the presence of or the predisposition to develop colorectal cancer.

Abstract: A system (400), apparatus (300), and method (200) are provided to simultaneously select TV programs for recording and watching during a certain time period [b, e] having a beginning time b and an ending time e. For each TV program a value is provided for receiving and recording and an additional value for watching. The values represent the preferences of a viewer. A dynamic programming approach is provided that solves the selection and viewing problem to optimality (guaranteed). The key idea behind the DP approach is the definition of the states, which represent all relevant information of previous steps needed to be able to judge a following step. A state definition includes time points at which the tuners are available after having received a program, and the time point at which the viewer is available again for watching the next program. Using this state definition, the present invention recursively expresses and calculates the effect of choosing a certain program for recording and/or watching.