Patents by Inventor Wilhelmus Johannes Theodorus Alexander KREBBER

Wilhelmus Johannes Theodorus Alexander KREBBER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT OF DISEASES RELATED TO HEPATITIS B VIRUS
    Publication number: 20230242590
    Abstract: The invention provides novel immunogenic peptides derived from the X protein and polymerase protein of hepatitis B virus (HBV). The peptides contain epitopes that are well-conserved across multiple HBV variants and are derived from regions of proteins that are essential for viral replication. Moreover, the novel HBV antigens bind multiple HLA types and epitopes that elicit IFN? responses in PBMCs from HBV resolvers have been identified.
    Type: Application
    Filed: December 4, 2020
    Publication date: August 3, 2023
    Applicants: ISA Pharmaceuticals B.V., Erasmus University Medical Center Rotterdam
    Inventors: Sonja Ingrid Buschow, Monica Theodora Antonetta de Beijer, Miranda Bernardina Johanna Molenaar, Thomas Johannes Maria Beenakker, Wilhelmus Johannes Theodorus Alexander Krebber, Cornelis Johannes Maria Melief, Anna-Sophia Wiekmeijer, Peter van Rijn, Diahann Talia Satirah Ludovica Jansen, Wilhelmus Johannes Elisabeth van Esch
  • Synthetic long peptides (SLP) for therapeutic vaccination against Hepatitis B virus infection
    Patent number: 10898567
    Abstract: The present invention relates to the fields of medicine and immunology. In particular, it relates to novel peptides that may be used in the treatment and/or prevention of a Hepatitis B viral infection and/or an Hepatitis B related disease or condition.
    Type: Grant
    Filed: July 1, 2019
    Date of Patent: January 26, 2021
    Assignee: ISA PHARMACEUTICALS B.V.
    Inventors: Wilhelmus Johannes Theodorus Alexander Krebber, Johan Herman Kessler, Cornelis Joseph Maria Melief, Kitty Michelle Corinne Kwappenberg
  • SYNTHETIC LONG PEPTIDES (SLP) FOR THERAPEUTIC VACCINATION AGAINST HEPATITIS B VIRUS INFECTION
    Publication number: 20190314494
    Abstract: The present invention relates to the fields of medicine and immunology. In particular, it relates to novel peptides that may be used in the treatment and/or prevention of a Hepatitis B viral infection and/or an Hepatitis B related disease or condition.
    Type: Application
    Filed: July 1, 2019
    Publication date: October 17, 2019
    Applicant: ISA Pharmaceuticals B.V.
    Inventors: Wilhelmus Johannes Theodorus Alexander KREBBER, Johan Herman KESSLER, Cornelis Joseph Maria MELIEF, Kitty Michelle Corinne KWAPPENBERG
  • Synthetic long peptides (SLP) for therapeutic vaccination against hepatitis B virus infection
    Patent number: 10376576
    Abstract: The present invention relates to the fields of medicine and immunology. In particular, it relates to novel peptides that may be used in the treatment and/or prevention of a Hepatitis B viral infection and/or an Hepatitis B related disease or condition.
    Type: Grant
    Filed: June 1, 2015
    Date of Patent: August 13, 2019
    Assignee: ISA Pharmaceuticals B.V.
    Inventors: Wilhelmus Johannes Theodorus Alexander Krebber, Johan Herman Kessler, Cornelis Joseph Maria Melief, Kitty Michelle Corinne Kwappenberg
  • SYNTHETIC LONG PEPTIDES (SLP) FOR THERAPEUTIC VACCINATION AGAINST HEPATITIS B VIRUS INFECTION
    Publication number: 20170246293
    Abstract: The present invention relates to the fields of medicine and immunology. In particular, it relates to novel peptides that may be used in the treatment and/or prevention of a Hepatitis B viral infection and/or an Hepatitis B related disease or condition.
    Type: Application
    Filed: June 1, 2015
    Publication date: August 31, 2017
    Applicant: ISA Pharmaceuticals B.V.
    Inventors: Wilhelmus Johannes Theodorus Alexander KREBBER, Johan Herman KESSLER, Cornelis Joseph Maria MELIEF, Kitty Michelle Corinne KWAPPENBERG