Abstract: A compound of formula (I), or a pharmaceutically acceptable salt thereof.

Abstract: The present disclosure pertains to a system for facilitating configuration modifications for a patient interface computer system based on an equivalent effort parameter. In some embodiments, the system obtains (i) one or more first measurements associated with a first subject, the first subject having a clinical coefficient, (ii) one or more second measurements associated with a second subject. The system determines (i) a first effort parameter based on the one or more first measurements, (ii) a second effort parameter based on the one or more second measurements, and (iii) an equivalent effort factor for the first subject based on the one or more first measurements, the one or more second measurements, and the clinical coefficient. The system causes a configuration of the patient interface computer system to be modified based on the equivalent effort factor.

Abstract: The present invention relates to a container base for holding live poultry, a container segment for holding live poultry that can be stacked onto such a container base, and a container cover as well as to a container assembly for holding live poultry, comprising such a container base and at least one such container segment placed on top of the container base. Furthermore the invention also relates to a method for loading the container assembly according the present invention.

Abstract: In embodiments, aerosol-type devices are provided. The devices have a main body comprising a pressure chamber, with pressure piston and pressure spring, and a piston chamber which draws liquid from a reservoir and fills the pressure chamber as a user performs compression and release strokes. The piston chamber has both inlet and outlet valves. In a dispensing head a valve is provided to regulate the flow strength and preclude leakage. Once the liquid is sufficiently pressurized, it is dispensed by a user opening an activation valve, and spray can be abruptly stopped by closing the activation valve. In alternate embodiments, without an activation valve, once the liquid is pressurized, continuous spray occurs until the pressure chamber is fully emptied. Pumping the trigger before the pressure chamber is fully emptied achieves continuous spray. When the input volume is greater than the volume of the pressure chamber volume, continuous spray with fewer pumping strokes occurs.

Abstract: Dispensing devices can include buffers. This obviates the need for continually pumping the device to dispense spray or foam. A buffer can be spring loaded, spring loaded combination, elastomeric or gas, and can be in line or adjacent to a piston chamber. Such sprayers and foamers can be mounted upside down. With a buffer, a piston chamber can deliver a greater amount of liquid per unit time than can be dispensed through the nozzle(s). The fraction of liquid that cannot be dispensed can be sent to the buffer for dispensing after the piston downstroke has completed. Volume of the piston chamber and buffer, pressure response of the buffer, throughput of the nozzle, and the minimum opening pressure of the outlet valve can be arranged to restrict the outlet pressures of liquid droplets exiting the nozzle within a defined range.

Abstract: The present invention relates nucleic acid constructs for the production of recombinant parvoviral (e.g. adeno-associated viral) vectors in insect cells, to insect cells comprising such constructs and to methods wherein the cells are used to produce recombinant parvoviral virions. The insect cells preferably comprise a first nucleotide sequence encoding the parvoviral rep proteins whereby the initiation codon for translation of the parvoviral Rep78 protein is a suboptimal initiation codon that effects partial exon skipping upon expression in insect cells. The insect cell further comprises a second nucleotide sequence comprising at least one parvoviral (AA V) inverted terminal repeat (ITR) nucleotide sequence and a third nucleotide sequence comprising a sequences coding for the parvoviral capsid proteins.

Abstract: An extreme ultraviolet radiation (EUV) source, including: a vessel having an inner vessel wall and an intermediate focus (IF) region; an EUV collector disposed inside the vessel, the EUV collector including a reflective surface configured to reflect EUV radiation toward the intermediate focus region, the reflective surface configured to directionally face the IF region of the vessel; a showerhead disposed along at least a portion of the inner vessel wall, the showerhead including a plurality of nozzles configured to introduce gas into the vessel; and one or more exhausts configured to remove gas introduced into the vessel, the one or more exhausts being oriented along at least a portion of the inner vessel wall so that the gas is caused to flow away from the EUV collector.

Abstract: A preform can be made from two different materials that do not bond together by a bi-injection process, using the same mold. First an outer preform can be fashioned first, then an inner preform molded through a center hole in the outer preform, and the preforms connected. Inner/outer preform materials can be different, e.g., PET/polyolefin or polyamide, or the same, e.g., PET/PET. To prevent mutual bonding during molding of the second, a non-stick coating can be sprayed on a surface portion of the first preform prior to molding, the second. Manufacturing order can be either outer/inner, or inner/outer, and the non-stick coating sprayed on the inside/outside of the perform first molded.

Abstract: An OLED lighting module comprising a support (2); an OLED lighting panel (3) with an emissive side with emissive and non-emissive areas (38) and an opposite side which comprises an OLED substrate (31), an OLED light-generating unit and a circuit board (34); an opaque liner with a first section (41) that covers at least part of the non-emitting areas (38) over the OLED substrate and a second section (42) that extend past the edges of the OLED substrate on the emissive side of the OLED panel; and an opaque bezel (6) in contact with the support (20), the opaque bezel (6) covering at least part of the second section (42) of the opaque liner but not the first section (41) of the opaque liner. By covering only that portion of an opaque liner that extends past the edges of the OLED substrate with a bezel and not the OLED substrate itself, the module can be made thin.

Abstract: An extreme ultraviolet radiation (EUV) source, including: a vessel having an inner vessel wall and an intermediate focus (IF) region; an EUV collector disposed inside the vessel, the EUV collector including a reflective surface configured to reflect EUV radiation toward the intermediate focus region, the reflective surface configured to directionally face the IF region of the vessel; a showerhead disposed along at least a portion of the inner vessel wall, the showerhead including a plurality of nozzles configured to introduce gas into the vessel; and one or more exhausts configured to remove gas introduced into the vessel, the one or more exhausts being oriented along at least a portion of the inner vessel wall so that the gas is caused to flow away from the EUV collector.

Abstract: A method of processing a substrate includes: providing a substrate with a layer of photosensitive material on a surface of the substrate; and removing at least part of the photosensitive material from around an outer edge of the layer of photosensitive material so as to generate an edge, having a radial width, around the layer of photosensitive material remaining on the surface of the substrate, wherein the photosensitive material varies in thickness forming a thickness profile across the radial width and the removing is controlled so as to generate variation in the thickness profile along the length of the edge, and/or wherein the removing is controlled so as to generate a rough edge around the layer of photosensitive material remaining on the surface of the substrate.

Abstract: A personal care device including at least one sensor (28) configured to obtain sensor data including information about a user; a controller (30) having a feature extraction module (230) and a classifier (240), the feature extraction module configured to extract one or more features from the obtained sensor data, the classifier configured to determine a status of a user based on the extracted one or more features; and a personal care device (10) configured to provide a personal care function and receive one or more control signals to adjust the personal care function based on a determined status of at least a portion of the user's body.

Abstract: The invention relates to a method and apparatus for providing feedback to a user, in particular relating to the fall risk of the user and/or relating to advice to reduce the fall risk of the user. According to an embodiment, there is provided an apparatus for providing feedback to a user, the apparatus comprising a user interface for providing feedback to the user; and a processing unit.

Abstract: A system (10) and method for selecting a mouthpiece (25) for a user. The method includes receiving a signal with a personal care system (10) to initiate oral arch measurements using a personal care device (12). Data is collected from a position sensor (16) related to a location of a probe (14) of the personal care device as the probe is moved about an oral arch of the user. A controller (18) of the personal care system determines a dimension of the oral arch from the data. The controller selects a mouthpiece for the user based on the dimension of the oral arch. Information identifying the mouthpiece is transmitted to the user or other intended recipient.

Abstract: The present invention relates to the fields of medicine and immunology. In particular, it relates to novel peptides that may be used in the treatment and/or prevention of a Hepatitis B viral infection and/or an Hepatitis B related disease or condition.

Abstract: A preform can be made from two different materials that do not bond together by a bi-injection process, using the same mold. First an outer preform can be fashioned, then an inner preform molded through a center hole in the bottom of the outer preform, and the preforms connected. Inner/outer preform materials can be different, e.g., PET/polyolefin or polyamide, or same, e.g., PET/PET. To prevent mutual bonding during molding of the second, a non-stick coating can be sprayed on a surface portion of the first preform prior to molding the second. Manufacturing order can be either outer/inner, or inner/outer, and the non-stick coating sprayed on the inside/outside of the preform first molded.

Abstract: A method (200) for determining a position and an orientation of a portion of a handheld personal care device relative to a user's body (50), comprising: providing (210) a handheld personal care device comprising at least one energy source (20) and at least one detector (22), both the at least one energy source and the at least one detector located within the handheld personal care device, the at least one energy source arranged at a first position and having a first orientation within the handheld personal care device; emitting (220) energy in a three dimensional space surrounding the handheld personal care device; detecting (230) a portion of the energy emitted; generating (240) sensor data; extracting (250) one or more features from the generated sensor data; and estimating (260) a position and an orientation of a portion of the handheld personal care device relative to the user's body based on the extracted one or more features.

Abstract: An in-line coating machine adapted to coat food products with a particulate coating material has a food products conveyor; a coating device; an excess coating material separation station; an excess coating material recovery conveyor; and a particulate coating material elevator device. An elevator device fill assembly along the recovery conveyor is configured to fill the elevator device with recovered excess coating material. An adjustable discharge opening device controls a discharge opening in the recovered excess coating material bed support. An adjustable upper layer diverter device engages an upper layer of the recovered excess coating material bed passing over the recovered excess coating material bed support and diverts at least a portion of the upper layer at an adjustable rate into the particulate coating material elevator device.

Abstract: A method of anti-fouling of a surface while said surface is at least partially submersed in an liquid environment, comprising: providing an anti-fouling light; distributing at least part of the light through an optical medium comprising a silicone material and/or UV grade fused silica; emitting the anti-fouling light from the optical medium and from the surface.

Abstract: In exemplary embodiments of the present invention, “Flairosol” dispensing devices can be provided. Such devices utilize a combination of Flair® technology, pre-compression valves and aerosol-like pressurization of the dispensed liquid. Such a dispensing device has, for example, a main body comprising a pressure chamber, the latter being provided with a pressure piston and a pressure spring. The device further has a piston and a piston chamber which draws liquid from a container, for example, the inner container of a Flair® bottle, and fills the pressure chamber with that liquid as a user operates a trigger in various compression and release strokes. The piston chamber has both an inlet valve and an outlet valve, which serve to prevent backflow.