Patents by Inventor Wilhelmus Theodorus Antonius Maria De Laat
Wilhelmus Theodorus Antonius Maria De Laat has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230413882Abstract: The present invention relates to a process for producing single cell protein, wherein a thermophilic fungus is grown a fermentable carbon-rich feedstock at a high temperature and at an acidic pH. This allows for a cost effective fermentation process that can to be run under non-sterile conditions and without additional cooling requirements. The process can be used to convert by-products or waste from agriculture or food production, or organic fractions of municipal solid waste into valuable single cell protein that can be applied as dietary source of protein or protein supplement in human food or animal feed.Type: ApplicationFiled: May 30, 2023Publication date: December 28, 2023Applicant: The Protein Brewery B.V.Inventors: Wilhelmus Theodorus Antonius Maria de Laat, Joan Sebastian Gallego Murillio
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Publication number: 20230240325Abstract: The present invention relates to compositions comprising biomass of a thermophilic fungus for use as an ingredient in food products, beverages, pet foods or animal feed. Due to its nutritional composition the biomass of the thermophilic fungus can be used as a source of protein and/or amino acids, including essential amino acids; lipids, including oleic and linoleic acids; dietary fiber; choline and vitamins such as vitamin E; and minerals such as iron. The biomass of the thermophilic fungus is available as a compressed biomass cake or as a dried powder. As such the biomass of the thermophilic fungus is suitable as ingredient in meat replacers, and in hybrid meat products. In the form of dried powder the biomass of the thermophilic fungus can be easily mixed with other ingredients to produce bakery products such as bread or soups.Type: ApplicationFiled: June 23, 2021Publication date: August 3, 2023Applicant: The Protein Brewery B.V.Inventors: Elisa Leune, Kirsten Knobel, Ap de Haan, Wilhelmus Theodorus Antonius Maria de Laat
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Patent number: 11707078Abstract: The present invention relates to a process for producing single cell protein, wherein a thermophilic fungus is grown a fermentable carbon-rich feedstock at a high temperature and at an acidic pH. This allows for a cost effective fermentation process that can to be run under non-sterile conditions and without additional cooling requirements. The process can be used to convert by-products or waste from agriculture or food production, or organic fractions of municipal solid waste into valuable single cell protein that can be applied as dietary source of protein or protein supplement in human food or animal feed.Type: GrantFiled: August 11, 2017Date of Patent: July 25, 2023Assignee: The Protein Brewery B.V.Inventors: Wilhelmus Theodorus Antonius Maria de Laat, Joan Sebastian Gallego Murillio
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Publication number: 20230212634Abstract: The present invention relates to the animal-free production of animal-derived proteins for human consumption by expression of such proteins, e.g. ovalbumin, in fungal cells. The invention relates to fungal cells modified for the production of animal-derived proteins, such as ovalbumin and to methods wherein these cells are used for the production of animal-derived proteins.Type: ApplicationFiled: January 14, 2021Publication date: July 6, 2023Applicant: The Protein Brewery B.V.Inventors: Joyce Josephine Elisabeth Arnouts, María Vázquez Vitali, Lucie Parenicová, Niels Lauret, Maloe Kleine Haar, Jos Reijngoud, Stefan Robert Marsden, Wilhelmus Theodorus Antonius Maria De Laat
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Patent number: 11667935Abstract: The invention relates to a process for producing a fermentation product that comprises fermentation of a carbon source in a reactor with a cell, capable of converting sugar, glycerol and acetic acid, wherein the carbon source comprises sugar and acetic acid, comprising the following steps: a) Inoculating a optionally diluted carbon source with the cell; b) optionally fermenting the reactor in batch mode; c) adding carbon source comprising glycerol and optionally sugar gradually to the reactor; d) after sufficient fermentation time, isolation of fermentation product from the reactor, e) optionally keeping the remaining fraction after isolation of step d) as spent broth; and f) optionally using the spent broth in step a) to dilute the carbon source.Type: GrantFiled: November 12, 2020Date of Patent: June 6, 2023Assignee: DSM IP ASSETS B.V.Inventors: Hans Marinus Charles Johannes De Bruijn, Wilhelmus Theodorus Antonius Maria De Laat, Paul Klaassen
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Publication number: 20230148627Abstract: The invention relates to a method for pasteurising a biomass, for example a fungal biomass, wherein the biomass is pasteurised using specific time and temperature parameters to obtain pasteurised biomass. The pasteurised biomass is suitable for use as a source of single-cell proteins in food products. The invention also relates to the pasteurised product, and to food products comprising it.Type: ApplicationFiled: March 5, 2021Publication date: May 18, 2023Applicant: The Protein Brewery B.V.Inventors: Kirsten Knobel, Ap de Haan, Wilhelmus Theodorus Antonius Maria de Laat
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Patent number: 11649471Abstract: The present invention relates to a process for the production of one or more fermentation product from a sugar composition, comprising the following steps: a) fermentation of the sugar composition in the presence of a yeast belonging to the genera Saccharomyces, Kluyveromyces, Candida, Pichia, Schizosaccharomyces, Hansenula, Kloeckera, Schwanniomyces or Yarrowia: and b) recovery of the fermentation product, wherein the yeast comprises the genes araA, araB and araD and the sugar composition comprises glucose, galactose and arabinose.Type: GrantFiled: March 12, 2021Date of Patent: May 16, 2023Assignee: DSM IP ASSETS B.V.Inventors: Paul Klaassen, Gijsberdina Pieternella Van Suylekom, Bianca Elisabeth Maria Gielesen, Nicolette Jasmijn Broers, Beate Wiedemann, Wilhelmus Theodorus Antonius Maria De Laat
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Publication number: 20230139404Abstract: The invention relates to a method for preparing a stable composition of single-cell protein by using antioxidants. The single-cell protein can be derived from a fungal biomass, wherein the biomass is pasteurised after antioxidants have been added to it. The stable composition has low TOTOX values and is suitable for use as a source of single-cell proteins in food or feed products. The invention also relates to the pasteurised product, and to food products comprising it.Type: ApplicationFiled: March 5, 2021Publication date: May 4, 2023Applicant: The Protein Brewery B.V.Inventors: Kirsten Knobel, Ap de Haan, Wilhelmus Theodorus Antonius Maria de Laat
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Publication number: 20230046934Abstract: The present invention relates to the use of a defoaming agent for preventing pellet morphology of thermophilic fungi when grown at acidic pH in chemically defined media. The invention pertains to processes for producing a fermentation product, wherein the thermophilic fungus, e.g. a Rhizomucor species, is grown in submerged culture at acidic pH in a chemically defined medium and wherein the strain is cultured in the presence of a defoaming agent. The defoaming agent can be a vegetable oil such as olive or sun flower oil and the fermentation product can be single cell protein in the form of biomass of the thermophilic fungus for use as a dietary source of protein.Type: ApplicationFiled: January 22, 2021Publication date: February 16, 2023Applicant: The Protein Brewery B.V.Inventors: Kirsten Knobel, Ap De Haan, Wilhelmus Theodorus Antonius Maria De Laat
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Publication number: 20210198701Abstract: The present invention relates to a process for the production of one or more fermentation product from a sugar composition, comprising the following steps: a) fermentation of the sugar composition in the presence of a yeast belonging to the genera Saccharomyces, Kluyveromyces, Candida, Pichia, Schizosaccharomyces, Hansenula, Kloeckera, Schwanniomyces or Yarrowia: and b) recovery of the fermentation product, wherein the yeast comprises the genes araA, araB and araD and the sugar composition comprises glucose, galactose and arabinose.Type: ApplicationFiled: March 12, 2021Publication date: July 1, 2021Inventors: Paul KLAASSEN, Gijsberdina Pieternella VAN SUYLEKOM, Bianca Elisabeth Maria GIELESEN, Nicolette Jasmijn BROERS, Beate WIEDEMANN, Wilhelmus Theodorus Antonius Maria DE LAAT
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Patent number: 10982235Abstract: The present invention relates to a process for the production of one or more fermentation product from a sugar composition, comprising the following steps: a) fermentation of the sugar composition in the presence of a yeast belonging to the genera Saccharomyces, Kluyveromyces, Candida, Pichia, Schizosaccharomyces, Hansenula, Kloeckera, Schwanniomyces or Yarrowia: and b) recovery of the fermentation product, wherein the yeast comprises the genes araA, araB and araD and the sugar composition comprises glucose, galactose and arabinose.Type: GrantFiled: February 22, 2019Date of Patent: April 20, 2021Assignee: DSM IP ASSETS B.V.Inventors: Paul Klaassen, Gijsberdina Pieternella Van Suylekom, Bianca Elisabeth Maria Gielesen, Nicolette Jasmijn Broers, Beate Wiedemann, Wilhelmus Theodorus Antonius Maria De Laat
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Patent number: 10945439Abstract: The present invention relates Pseudomonas strains and consortia thereof that are useful in protecting plants against microbial plant diseases caused by pathogens such as Ralstonia, Clavibacter, Erwinia, Curtobacterium, Fusarium, Phytophthora and Helminthosporium. The Pseudomonas strains were selected on the basis of their antagonistic abilities against plant pathogens such as production of antimicrobial compounds, direct inhibition of growth of plant pathogens, competition of carbon or nitrogen sources and endophytic features such as anaerobic growth on nitrate as electron acceptor and growth on arabinose as carbon source. The invention further relates to compositions comprising the strains or consortia of the invention, preferably lyophilized compositions, and to methods wherein they are used in protecting a wide variety of plants against a wide variety of microbial plant diseases.Type: GrantFiled: April 12, 2017Date of Patent: March 16, 2021Assignee: Wim de Laat Consultancy B.V.Inventors: Wilhelmus Theodorus Antonius Maria de Laat, Erwin Suir, Ap de Haan, Joyce Josephine Elisabeth Arnouts
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Publication number: 20210071205Abstract: The invention relates to a process for producing a fermentation product that comprises fermentation of a carbon source in a reactor with a cell, capable of converting sugar, glycerol and acetic acid, wherein the carbon source comprises sugar and acetic acid, comprising the following steps: a) Inoculating a optionally diluted carbon source with the cell; b) optionally fermenting the reactor in batch mode; c) adding carbon source comprising glycerol and optionally sugar gradually to the reactor; d) after sufficient fermentation time, isolation of fermentation product from the reactor, e) optionally keeping the remaining fraction after isolation of step d) as spent broth; and f) optionally using the spent broth in step a) to dilute the carbon source.Type: ApplicationFiled: November 12, 2020Publication date: March 11, 2021Inventors: Hans Marinus Charles Johannes DE BRUIJN, Wilhelmus Theodorus Antonius Maria DE LAAT, Paul KLAASSEN
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Patent number: 10883122Abstract: The invention relates to a process for producing a fermentation product that comprises fermentation of a carbon source in a reactor with a cell, capable of converting sugar, glycerol and acetic acid, wherein the carbon source comprises sugar and acetic acid, comprising the following steps: a) Inoculating a optionally diluted carbon source with the cell; b) optionally fermenting the reactor in batch mode; c) adding carbon source comprising glycerol and optionally sugar gradually to the reactor; d) after sufficient fermentation time, isolation of fermentation product from the reactor, e) optionally keeping the remaining fraction after isolation of step d) as spent broth; and f) optionally using the spent broth in step a) to dilute the carbon source.Type: GrantFiled: December 17, 2015Date of Patent: January 5, 2021Assignee: DSM IP ASSETS B.V.Inventors: Hans Marinus Charles Johannes De Bruijn, Wilhelmus Theodorus Antonius Maria De Laat, Paul Klaassen
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Publication number: 20200123577Abstract: The present invention describes a method for the treatment of lignocellulosic material which method comprises contacting said lignocellulosic material with a composition comprising two or more enzyme activities, said enzyme activities being cellulase and/or hemicellulase activities, wherein the pH during the treatment is about 4.5 or lower, and the treatment is carried out at a dry matter content of 15% or more.Type: ApplicationFiled: November 7, 2019Publication date: April 23, 2020Inventors: Wilhelmus Theodorus Antonius Maria DE LAAT, Manoj Kumar, Margot Elisabeth Francois Schooneveld-Bergmans
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Patent number: 10557153Abstract: The present invention describes a method for the treatment of lignocellulosic material which method comprises contacting said lignocellulosic material with a composition comprising two or more enzyme activities, said enzyme activities being cellulase and/or hemicellulase activities, wherein the pH during the treatment is about 4.5 or lower, and the treatment is carried out at a dry matter content of 15% or more.Type: GrantFiled: August 4, 2009Date of Patent: February 11, 2020Assignee: DSM IP ASSETS B.V.Inventors: Wilhelmus Theodorus Antonius Maria De Laat, Manoj Kumar, Margot Elisabeth Francoise Schooneveld-Bergmans
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Publication number: 20190177748Abstract: The present invention relates to a process for the production of one or more fermentation product from a sugar composition, comprising the following steps: a) fermentation of the sugar composition in the presence of a yeast belonging to the genera Saccharomyces, Kluyveromyces, Candida, Pichia, Schizosaccharomyces, Hansenula, Kloeckera, Schwanniomyces or Yarrowia: and b) recovery of the fermentation product, wherein the yeast comprises the genes araA, arae and araD and the sugar composition comprises glucose, galactose and arabinose.Type: ApplicationFiled: February 22, 2019Publication date: June 13, 2019Inventors: Paul KLAASSEN, Gijsberdina Pieternella VAN SUYLEKOM, Bianca Elisabeth Maria GIELESEN, Nicolette Jasmijn BROERS, Beate WIEDEMANN, Wilhelmus Theodorus Antonius Maria DE LAAT
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Publication number: 20190174809Abstract: The present invention relates to a process for producing single cell protein, wherein a thermophilic fungus is grown a fermentable carbon-rich feedstock at a high temperature and at an acidic pH. This allows for a cost effective fermentation process that can to be run under non-sterile conditions and without additional cooling requirements. The process can be used to convert by-products or waste from agriculture or food production, or organic fractions of municipal solid waste into valuable single cell protein that can be applied as dietary source of protein or protein supplement in human food or animal feed.Type: ApplicationFiled: August 11, 2017Publication date: June 13, 2019Applicant: Wim de Laat Consultancy B.V.Inventors: Wilhelmus Theodorus Antonius Maria de Laat, Joan Sebastian Gallego Murillio
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Publication number: 20190116800Abstract: The present invention relates Pseudomonas strains and consortia thereof that are useful in protecting plants against microbial plant diseases caused by pathogens such as Ralstonia, Clavibacter, Envinia, Curtobacterium, Fusarium, Phytophthora and Helminthosporium. The Pseudomonas strains were selected on the basis of their antagonistic abilities against plant pathogens such as production of antimicrobial compounds, direct inhibition of growth of plant pathogens, competition of carbon or nitrogen sources and endophytic features such as anaerobic growth on nitrate as electron acceptor and growth on arabinose as carbon source. The invention further relates to compositions comprising the strains or consortia of the invention, preferably lyophilized compositions, and to methods wherein they are used in protecting a wide variety of plants against a wide variety of microbial plant diseases.Type: ApplicationFiled: April 12, 2017Publication date: April 25, 2019Applicant: Wim de Laat Consultancy B.V.Inventors: Wilhelmus Theodorus Antonius Maria de Laat, Erwin Suir, Ap de Haan, Joyce Josephine Elisabeth Arnouts
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Patent number: 10260075Abstract: The present invention relates to a process for the production of one or more fermentation product from a sugar composition, comprising the following steps: a) fermentation of the sugar composition in the presence of a yeast belonging to the genera Saccharomyces, Kluyveromyces, Candida, Pichia, Schizosaccharomyces, Hansenula, Kloeckera, Schwanniomyces or Yarrowia, and b) recovery of the fermentation product, wherein the yeast comprises the genes araA, araB and araD and the sugar composition comprises glucose, galactose and arabinose.Type: GrantFiled: January 17, 2017Date of Patent: April 16, 2019Assignee: DSM IP ASSETS B.V.Inventors: Paul Klaassen, Gijsberdina Pieternella Van Suylekom, Bianca Elisabeth Maria Gielesen, Nicolette Jasmijn Broers, Beate Wiedemann, Wilhelmus Theodorus Antonius Maria De Laat