Patents by Inventor Wilhem Dirks

Wilhem Dirks has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for producing a pharmaceutical preparation of PDGF-AB
    Patent number: 5935819
    Abstract: The recombinant production of PDGF-AB in mammalian cells is disclosed by means of a bicistronic vector system in which an IRES sequence is located between the first and second cistrons and in which the B chain coding gene is located in the first cistron. The disclosed expression unit allows the equilmolar expression of the A and B polypeptide chains.
    Type: Grant
    Filed: January 2, 1997
    Date of Patent: August 10, 1999
    Inventors: Wolfram Eichner, Volker Achterberg, Albrecht Dorschner, Wolfgang Meyer-Ingold, Heiko Mielke, Wilhem Dirks, Manfred Wirth, Hansjorg Hauser
  • Preparation of heterodimeric PDGF-AB using a bicistronic vector system in mammalian cells
    Patent number: 5665567
    Abstract: The recombinant production of PDGF-AB in mammalian cells is disclosed by means of a bicistronic vector system in which an IRES sequence is located between the first and second cistrons and in which the B chain coding gene is located in the first cistron. The disclosed expression unit allows the equimolor expression of the A and B polypeptide chains.
    Type: Grant
    Filed: April 24, 1995
    Date of Patent: September 9, 1997
    Assignees: Beiersdorf AG, Gesellschaft fur Biotechnologische Forschung mbH
    Inventors: Wolfram Eichner, Volker Achterberg, Albrecht Dorschner, Wolfgang Meyer-Ingold, Heiko Mielke, Wilhem Dirks, Manfred Wirth, Hansjorg Hauser