Abstract: The present invention relates to 11-O-desmethylmacbecin analogues that are useful, e.g. in the treatment of cancer, B-cell malignancies, malaria, fungal infection, diseases of the central nervous system and neurodegenerative diseases, diseases dependent on angiogenesis, autoimmune diseases and/or as a prophylactic pretreatment for cancer. The present invention also provides methods for the production of these compounds and their use in medicine, in particular in the treatment and/or prophylaxis of cancer or B-cell malignancies.

Abstract: A system and method for employing registers for data transfer in multiple hardware contexts and programming engines to facilitate high performance data processing. The system and method includes a processor that includes programming engines with registers for transferring data from one of the registers residing in an executing programming engine to a subsequent one of the registers residing in an adjacent programming engine.

Abstract: A bacterial detection sampling device comprising: a sampling medium for receiving a bacterial sample; and a plurality of bacteriophage. The bacteriophage are located on or in the sampling medium. Each bacteriophage comprises a nucleic acid encoding a protein capable of emitting light at an output wavelength.

Abstract: A processor (403) is provided for processing identifiers of video and/or audio material. The processor is for use with a video and/or audio material processing device. The device has a plurality of inputs (IN) for receiving respective pieces of material to be processed, the pieces having respective identifiers, and an output (OUT) at which is output processed material, which is a combination of the input material, and a state output at which data defining the state of the device is output. The processor is arranged to: detect (405) the identifiers of the input material; determine (406) from the state data the combination of the input material forming the output material; generate (407) an identifier for the output material; and associate the identifier of the output material with the identifiers of the input material used to form the output material. Identifiers preferably indicate whether the material emanates from a recorder or from a live source.

Abstract: A system for storing a biological sample for transfer between two different environments is provided. The system includes a first container defining a first container interior, and a second container defining a second container interior. A first closure is provided for enclosing the open end of the first container, with the first closure adapted to receive a sample holder. A second closure is also provided for enclosing the open end of the second container. The first container is adapted to removably receive the sample holder therein when the first closure encloses the open end of the first container, and the second container is adapted to subsequently receive the same sample holder therein when the first closure encloses the open end of the second container.

Abstract: A portable medicine cooler and a method of operating the same. In one embodiment, the portable medicine cooler includes: (1) a shell having a grille and further having a door configured to provide access to a cavity within the shell for containing a medicine to be cooled, (2) a cooling and receiver structure coupled to the shell and including a thermoelectric cooler interposing a heat sink and a vial receiver and (3) electronic cooling control and medicine efficacy indication circuitry coupled to the cooling and receiving structure and including a processor, at least one temperature sensor configured to provide a signal to the processor indicating a temperature associated with the portable medicine cooler, a battery configured to provide power to the processor and an indicator selected from the group consisting of at least one light-emitting diode and a liquid-crystal display and configured to provide an indication of an operation of the portable medicine cooler.

Abstract: A process for the recovery of ethane, ethylene, propane, propylene, and heavier hydrocarbon components from a hydrocarbon gas stream is disclosed. The stream is cooled and divided into first and second streams. The first stream is further cooled to condense substantially all of it and is thereafter expanded to the fractionation tower pressure and supplied to the fractionation tower at a first mid-column feed position. The second stream is expanded to the tower pressure and is then supplied to the column at a second mid-column feed position. A vapor distillation stream is withdrawn from the column above the feed point of the second stream and is then directed into heat exchange relation with the tower overhead vapor stream to cool the vapor distillation stream and condense at least a part of it, forming a condensed stream. At least a portion of the condensed stream is directed to the fractionation tower as its top feed.

Abstract: A container for storing a biological sample is disclosed. The container includes a housing having a closed end, an open end, and a sidewall extending therebetween defining a container interior. The container has a removable closure for enclosing the open end of the housing and a sample holder for housing a biological sample detachably connected to the closure and insertable within the container interior. A port is disposed within the closure adjacent the sample holder to allow fluid to pass therethrough into the container interior. An injection device for engaging the port may also be provided. A first fluid may be initially provided within the container interior and a second fluid may be subsequently injected by the injection device through the port into the container interior.

Abstract: An input module obtains a media signal to be communicated to a destination system, after which an identification module identifies a plurality of segments within the media signal. A codec includes a selection module that automatically selects different compression methods to respectively compress at least two of the segments. The compression methods are automatically selected to produce a highest compression quality for the respective segments according to a set of criteria without exceeding a target data rate. A compression module within the codec then compresses the segments using the automatically-selected compression methods, after which an output module delivers the compressed segments to the destination system with an indication of which compression method was used to compress each segment.

Abstract: The present disclosure relates to a device, system and method of automated interpretation of medical prescription text. Prescription text may be entered into a user interface that may be analogous to a paper prescription entry such as manually written text. The system may then provide parsing, prompts and/or hints along with validity feedback as the prescription information is entered by the user.

Abstract: In a method and an arrangement for shimming a cylindrical magnet system, that has a cylindrical magnet having a bore therein with an axis extending therethrough, and a gradient coil assembly located within the bore, shimming is accomplished by stacking a number of planar pieces of shim material in each of said tubes, with each of the tubes having an axis parallel to the axis of the cylindrical magnet, and with the planar pieces of shim material and stacked in the tubes in respective planes that are perpendicular to the axis fo the cylindrical magnet.

Abstract: A data processing method for processing a sequence of platform independent instructions on a data processing apparatus comprising a CPU and at least one further processor is disclosed.

Abstract: A chair has a supporting frame, a seat portion, a back portion, and a recline mechanism. The mechanism moves the seat portion upon a reclining action of the back portion. The mechanism has a rear deformable member and a front deformable member operatively connecting the seat portion and the supporting frame. The recline mechanism also has a lower deformable member operatively connecting a lower part of the back portion and the supporting frame, and a puller member above the lower deformable member. The recline mechanism is configured such that as the back portion is reclined, the lower deformable member deforms and the puller member applies a rearward pulling action which causes the seat portion to move and the front and rear deformable members to deform.

Abstract: A magnetic resonance apparatus has an examination region to accommodate a patient to be examined, and a body coil that circumferentially encompasses the examination region and is designed for magnetic resonance examination of the patient. A gradient coil circumferentially encompasses the examination region and the body coil and is designed to detect the position of magnetic resonance measurement values. A basic field magnet is designed to form a basic magnetic field in the examination region for a patient examination to be conducted. The basic field magnet at least partially encompasses the examination region, the body coil and the gradient coil. A shim device is used that is designed to influence the basic magnetic field. Components of the shim device and components of the body coil are associated to exhibit a common distance relative to the longitudinal axis of symmetry of the examination region and thus encompass the examination region.

Abstract: Systems and methods for use in association with a master entity index system may allow data records to be grouped together into various entities, where each of the entities may represent a logical or physical item. These entities may also be associated with one another in a manner such that relationships between entities may likewise be represented. In one embodiment, an interface may be provided for use in conjunction with the master entity index system such that these various entities and relationships may be better managed, manipulated or visualized. This interface may allow a user to search for or otherwise obtain an entity, where a representation of this entity and one or more associated entities may be presented to the user along with representations of the relationships between these entities.

Abstract: Systems and methods are provided for issuing unique identification credentials to a plurality of devices, and their constituent components, in an industrial control system. Identification credentials are granted by an identification authority and conveyed to each of the credentialed devices and/or component through an identity token. The identification credentials include (1) a unique device identifier, (2) an identification authority component identifier, and (3) an indication of the location of the identification authority component. To secure the issued credentials, such credentials are encrypted and the identification token can be embedded with biometrics features. Identification credentials provide for the following prominent features: (i) Secure access to a device form a client and (ii) determination a topology of a set of credentialed devices in an industrial control system. The topology is network agnostic and facilitates organizational modeling of processes in the industrial control system.

Abstract: A barrier transfer device includes a cantilevered support arm and a carriage coupled to the support arm. The carriage includes at least a pair of barrier interface members extending downwardly from the support arm. The barrier interface members are configured to engage a barrier on opposite sides thereof when the barrier. A system for transferring a barrier includes a transfer vehicle having an outermost portion on each of first and second opposite sides of the transfer vehicle. The cantilevered support arm is coupled to the transfer vehicle and extends laterally outwardly past the outermost portion of the transfer vehicle on the first side of the transfer vehicle. A moveable barrier system includes at least one barrier having first and second sides and a bottom adapted to be supported by a ground surface and a transfer vehicle having a barrier interface element engaging only a first side of said barrier. Methods for transferring a barrier are also provided.

Abstract: A system and method for tracking communication for determining device states. Communication between devices is observed and a respective state of at least one device is inferred. The inference is formed without directly communicating with the device. Various states of the devices include unknown, used, unfulfilled, virtual, omitted, and automatic. The respective state of a device is unknown when the observation shows that the device fails to respond to communication. The respective state of the device is unfulfilled when an ARP request comprising a destination address for the device is observed, and the device does not respond to the ARP request prior to expiration of a time limit. The respective state of a device is determined to be virtual when the observation shows that the device received a packet when its respective state was unfulfilled, and the device did not send a reply to the packet within a time limit.