Patents by Inventor Will MCLEAN

Will MCLEAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SOLUBILIZED COMPOSITIONS FOR CONTROLLED PROLIFERATION OF STEM CELLS / GENERATING INNER EAR HAIR CELLS USING GSK3 INHIBITORS: III
    Publication number: 20170252449
    Abstract: The present invention relates to compositions and methods of inducing the self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into hair cells.
    Type: Application
    Filed: March 2, 2017
    Publication date: September 7, 2017
    Inventors: Christopher LOOSE, Will MCLEAN, Megan HARRISON, Michael R. JIROUSEK
  • METHODS FOR CONTROLLED PROLIFERATION OF STEM CELLS / GENERATING INNER EAR HAIR CELLS USING N-(ALKYLCARBAMOYL)-1H-PYRAZOL-4-YL)-NICOTINAMIDE BASED COMPOUNDS
    Publication number: 20170252331
    Abstract: The present invention relates to methods of inducing the self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into hair cells. Specifically, the invention relates to methods of using compounds comprising a N-(1H-pyrazol-4-yl)-nicotinamide moiety having a Formula I: and pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: March 2, 2017
    Publication date: September 7, 2017
    Inventors: Christopher LOOSE, Will MCLEAN, Melissa HILL-DRZEWI
  • METHODS FOR CONTROLLED PROLIFERATION OF STEM CELLS / GENERATING INNER EAR HAIR CELLS USING 3-(PYRIDIN-2-YL)-1H-INDOL-2-OL BASED COMPOUNDS
    Publication number: 20170252348
    Abstract: The present invention relates to methods of inducing the self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into hair cells. Specifically, the invention relates to methods of using compounds comprising a 3-(pyridin-2-yl)-1H-indol-2-ol containing moiety having a Formula I: and pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: March 2, 2017
    Publication date: September 7, 2017
    Inventors: Christopher LOOSE, Will MCLEAN, Melissa HILL-DRZEWI
  • METHODS FOR CONTROLLED PROLIFERATION OF STEM CELLS / GENERATING INNER EAR HAIR CELLS USING 1,2,3,4-TETRAHYDRO-[1,4]DIAZEPINO[6,7, 1-HI]INDOLYL BASED COMPOUNDS
    Publication number: 20170252353
    Abstract: The present invention relates to methods of inducing the self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into hair cells. Specifically, the invention relates to methods of using compounds comprising a 1,2,3,4-tetrahydro-[1,4]diazepino[6,7, 1-hi]indole moiety having a Formula I and pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: March 2, 2017
    Publication date: September 7, 2017
    Inventors: Christopher LOOSE, Will MCLEAN, Melissa HILL-DRZEWI
  • THERMOREVERSIBLE COMPOSITIONS FOR ADMINISTRATION OF THERAPEUTIC AGENTS
    Publication number: 20170252448
    Abstract: The present invention relates to compositions and methods of inducing the self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into hair cells.
    Type: Application
    Filed: March 2, 2017
    Publication date: September 7, 2017
    Inventors: Christopher LOOSE, Will MCLEAN, Megan HARRISON, Michael R. JIROUSEK
  • SOLUBILIZED COMPOSITIONS FOR CONTROLLED PROLIFERATION OF STEM CELLS / GENERATING INNER EAR HAIR CELLS USING GSK3 INHIBITORS: II
    Publication number: 20170252329
    Abstract: The present invention relates to compositions and methods of inducing the self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into hair cells.
    Type: Application
    Filed: March 2, 2017
    Publication date: September 7, 2017
    Inventors: Christopher LOOSE, Will MCLEAN, Megan HARRISON, Michael R. JIROUSEK
  • SOLUBILIZED COMPOSITIONS FOR CONTROLLED PROLIFERATION OF STEM CELLS / GENERATING INNER EAR HAIR CELLS USING GSK3 INHIBITORS: I
    Publication number: 20170252340
    Abstract: The present invention relates to compositions and methods of inducing the self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into hair cells.
    Type: Application
    Filed: March 2, 2017
    Publication date: September 7, 2017
    Inventors: Christopher LOOSE, Will MCLEAN, Megan HARRISON, Michael R. JIROUSEK