Patents by Inventor Willaim Markland

Willaim Markland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Kallikrein-inhibiting "Kunitz Domain" proteins and analogues thereof
    Patent number: 5994125
    Abstract: Proteins are disclosed that are homologous to bovine pancreatic trypsin inhibitor (BPTI) Kunitz domains, and especially proteins that are homologous to lipoprotein-associated coagulation inhibitor (LACI) Kunitz domains, which inhibit one or more plasma and/or tissue kallikreins, and uses of such proteins in therapeutic and diagnostic methods also are disclosed. In particular, Kunitz domains derived from Kunitz domains of human origin and especially to the first Kunitz domain of LACI are disclosed.
    Type: Grant
    Filed: August 17, 1998
    Date of Patent: November 30, 1999
    Assignee: Dyax Corp.
    Inventors: Willaim Markland, Robert Charles Ladner
  • Kallikrein-inhibiting "kunitz domain" proteins and analogues thereof
    Patent number: 5795865
    Abstract: Proteins are disclosed that are homologous to bovine pancreatic trypsin inhibitor (BPTI) Kunitz domains, and especially proteins that are homologous to lipoprotein-associated coagulation inhibitor (LACI) Kunitz domains, which inhibit one or more plasma and/or tissue kallikreins, and uses of such proteins in therapeutic and diagnostic methods also are disclosed. In particular, Kunitz domains derived from Kunitz domains of human origin and especially to the first Kunitz domain of LACI are disclosed.
    Type: Grant
    Filed: September 25, 1996
    Date of Patent: August 18, 1998
    Assignee: Dyax Corp.
    Inventors: Willaim Markland, Robert Charles Ladner