Patents by Inventor Willard H. Dere

Willard H. Dere has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of reducing the risk of bone fracture
    Patent number: 7351414
    Abstract: The invention relates to a method for increasing the toughness and/or stiffness of bone and/or reducing the likelihood and/or severity of bone fracture by administering a parathyroid hormone. The method can be employed to increase toughness or stiffness of bone at a site of a potential or actual trauma, such as the hip or spine of a person at risk of or suffering from osteoporosis. The method of the invention can reduce the incidence of vertebral fracture, reduce the incidence of multiple vertebral fractures, reduce the severity of vertebral fractur and/or reduce the incidence of non-vertebral fracture.
    Type: Grant
    Filed: March 12, 2007
    Date of Patent: April 1, 2008
    Assignee: Eli Lilly and Company
    Inventors: Gregory A. Gaich, Willard H. Dere, Janet M. Hock
  • Method of increasing bone toughness and stiffness and reducing fractures
    Patent number: 7163684
    Abstract: The invention relates to a method for increasing the toughness and/or stiffness of bone and/or reducing the likelihood and/or severity of bone fracture by administering a parathyroid hormone. The method can be employed to increase toughness or stiffness of bone at a site of a potential or actual trauma, such as the hip or spine of a person at risk of or suffering from osteoporosis. The method of the invention can reduce the incidence of vertebral fracture, reduce the incidence of multiple vertebral fractures, reduce the severity of vertebral fracture, and/or reduce the incidence of non-vertebral fracture.
    Type: Grant
    Filed: April 5, 2005
    Date of Patent: January 16, 2007
    Assignee: Eli Lilly and Company
    Inventors: Gregory A. Gaich, Willard H. Dere, Janet M. Hock
  • Method of increasing bone toughness and stiffness and reducing fractures
    Patent number: 6977077
    Abstract: The invention relates to a method for increasing the toughness and/or stiffness of bone and/or reducing the likelihood and/or severity of bone fracture by administering a parathyroid hormone. The method can be employed to increase toughness or stiffness of bone at a site of a potential or actual trauma, such as the hip or spine of a person at risk of or suffering from osteoporosis. The method of the invention can reduce the incidence of vertebral fracure, reduce the incidence of multiple vertebral fractures, reduce the severity of vertebral fracture, and/or reduce the incidence of non-vertebral fracture.
    Type: Grant
    Filed: August 19, 1999
    Date of Patent: December 20, 2005
    Assignee: Eli Lilly and Company
    Inventors: Janet M. Hock, Gregory A. Gaich, Willard H. Dere
  • Method of increasing bone toughness and stiffness and reducing fractures
    Publication number: 20040033950
    Abstract: The invention relates to a method for increasing the toughness and/or stiffness of bone and/or reducing the likelihood and/or severity of bone fracture by administering a parathyroid hormone. The method can be employed to increase toughness or stiffness of bone at a site of a potential or actual trauma, such as the hip or spine of a person at risk of or suffering from osteoporosis. The method of the invention can reduce the incidence of vertebral fracture, reduce the incidence of multiple vertebral fractures, reduce the severity of vertebral fracture, and/or reduce the incidence of non-vertebral fracture.
    Type: Application
    Filed: May 22, 2003
    Publication date: February 19, 2004
    Inventors: Janet M. Hock, Gregory H. Gaich, Willard H. Dere
  • Methods of decreasing serum calcium levels
    Patent number: 5512583
    Abstract: A method of lowering serum calcium levels comprising administering to a human in need thereof an effective amount of a compound having the formula ##STR1## wherein R.sup.l and R.sup.3 are independently hydrogen, --CH.sub.3, ##STR2## wherein Ar is optionally substituted phenyl; R.sup.2 is selected from the group consisting of pyrrolidine, hexamethyleneamino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.
    Type: Grant
    Filed: January 30, 1995
    Date of Patent: April 30, 1996
    Assignee: Eli Lilly and Company
    Inventors: Susan M. Boss, Willard H. Dere