Abstract: An implantable medical device uses a sampling scheme to obtain digital representation from analog signals. The analog signals represent intracardiac activity. Generally, a detector detects the amplitude of the analog signals and generates first and second difference signals. The first difference signal is generated after detection of significant changes in the analog signal amplitude. The second difference signal is generated upon confirmation of the absence of significant changes in the analog signal amplitude over a predetermined period of time. A frequency selection is implemented to select the sampling frequency based on the first and second difference signal.

Abstract: An implantable medical device including a sampling scheme to obtain digital representation from analog signals is disclosed. The analog signals represent intracardiac activity. Generally, a detector detects the amplitude of the analog signals and generates first and second difference signals. The first difference signal is generated after detection of significant changes in the analog signal amplitude. The second difference signal is generated upon confirmation of the absence of significant changes in the analog signal amplitude over a predetermined period of time. A frequency selection is implemented to select the sampling frequency based on the first and second difference signal.

Abstract: A system and method for use in an implanted cardiac pacing device, whereby an optimal AV delay is determined at or near lower rate (pacing) limit (LRL) by determining measuring the variance, or instability, of the QT interval for a set of intervals. In one embodiment, asynchronous “LRL pacing” with a first programmed AV delay determines a measure of QT variance. The difference between the maximum QT and the minimum QT is expressed as QT difference (QTD). For each programmed AV delay the QT variance is again measured and the optimal AV delay produces minimum QTD. In another embodiment, AV delay is modulated around base values for a time. The difference between QT for the modulated AV and for the base AV (dQT) is measured at each base value, and the optimal AV delay corresponds to the smallest dQT.

Abstract: A system and method are provided for monitoring cardiac wall motion. A cardiac lead is provided with a motion sensor that is responsive to an excitation signal. The motion sensor signal induced by the excitation signal varies in time due to motion caused by myocardial wall motion. The time-varying motion sensor signal is obtained by sensing circuitry and provided to a processor for use in computing a wall motion parameter useful in assessing ventricular function. The processor provides wall motion parameter output for display or storage. Pacing parameters may be optimized according to wall motion parameter measurements obtained during iterative procedures using the lead-mounted motion sensor.

Abstract: A system and method for use in an implanted cardiac pacing device, whereby an optimal AV delay is determined at or near lower rate (pacing) limit (LRL) by determining measuring the variance, or instability, of the QT interval for a set of intervals. In one embodiment, asynchronous “LRL pacing” with a first programmed AV delay determines a measure of QT variance. The difference between the maximum QT and the minimum QT is expressed as QT difference (QTD). For each programmed AV delay the QT variance is again measured and the optimal AV delay produces minimum QTD. In another embodiment, AV delay is modulated around base values for a time. The difference between QT for the modulated AV and for the base AV (dQT) is measured at each base value, and the optimal AV delay corresponds to the smallest dQT.