Patents by Inventor Willem Bijleveld

Willem Bijleveld has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11999923
    Abstract: The present invention relates to a process for reducing an amount of intact phospholipids in a triacylglyceride oil comprising incubating the oil with a polypeptide having phospholipase A1 activity, wherein the polypeptide comprises a polypeptide having at least 80% identity to the mature amino acid sequence of SEQ ID NO: 1.
    Type: Grant
    Filed: May 6, 2019
    Date of Patent: June 4, 2024
    Assignee: DSM IP ASSETS B.V.
    Inventors: Ying Zha, Arjen Sein, Willem Bijleveld
  • Publication number: 20230250406
    Abstract: The present invention relates to a polypeptide having lipase activity wherein the polypeptide when aligned with the polypeptide according to SEQ ID NO: 1, comprises at least an amino acid substitution G414X, wherein the numbering of amino acid position(s) is/are defined with reference to SEQ ID NO: 1. The invention further relates to a process for preparing a product comprising an oil or fat comprising bringing an intermediary form of the product comprising oil or fat into contact with a polypeptide as disclosed herein and the use of a polypeptide as disclosed herein to saturated fatty acids in an oil or fat.
    Type: Application
    Filed: May 17, 2019
    Publication date: August 10, 2023
    Inventors: René Marcel DE JONG, Willem BIJLEVELD, Paul Frederick MUGFORD
  • Publication number: 20230080079
    Abstract: The present invention relates to a polypeptide having lipase activity wherein the polypeptide when aligned with the polypeptide according to SEQ ID NO: 1, comprises at least an amino acid substitution L410X and optionally one or more amino acid substitutions chosen from S365Q, S365N, L413M, G414A, G414S, G414V, G414T, V534L and V534l, wherein the 10 numbering of amino acid position(s) is/are defined with reference to SEQ ID NO: 1. The invention further relates to a process for preparing a product comprising an oil or fat comprising bringing an intermediary form of the product comprising oil or fat into contact with a polypeptide as disclosed herein and the use of a polypeptide as disclosed herein to saturated fatty acids in an oil or fat.
    Type: Application
    Filed: May 17, 2019
    Publication date: March 16, 2023
    Inventors: René Marcel DE JONG, Willem BIJLEVELD, Paul Frederick MUGFORD
  • Publication number: 20210371770
    Abstract: The present invention relates to a process for reducing an amount of intact phospholipids in a triacylglyceride oil comprising incubating the oil with a polypeptide having phospholipase A1 activity, wherein the polypeptide comprises a polypeptide having at least 80% identity to the mature amino acid sequence of SEQ ID NO: 1.
    Type: Application
    Filed: May 6, 2019
    Publication date: December 2, 2021
    Inventors: Ying ZHA, Arjen SEIN, Willem BIJLEVELD
  • Patent number: 10829748
    Abstract: The present invention relates to a polypeptide having lipase activity wherein the polypeptide, which, when aligned with a polypeptide according to SEQ ID NO: 1, comprises at least one amino acid substitution resulting in Ser (S), Ala (A) or Leu (L) at position 246, Trp (W) at position 307, Leu (L) at position 345, Ile (I) at position 365, and/or Phe (F) at position 534, wherein the position is defined with reference to SEQ ID NO: 1, wherein Ala(A) at position 1 in SEQ ID NO: 1 is counted as number 1 and a method for preparing the polypeptide. The present invention further relates to a process for preparing a food product wherein a polypeptide according to the present invention is used.
    Type: Grant
    Filed: June 8, 2017
    Date of Patent: November 10, 2020
    Assignee: DSM IP ASSETS B.V.
    Inventors: Rene Marcel De Jong, Willem Bijleveld, Evert Tjeerd Van Rij
  • Patent number: 10457890
    Abstract: The present invention relates to a polypeptide having phospholipase C activity, selected from the group consisting of i. a polypeptide comprising a mature polypeptide sequence of SEQ ID NO: 2; ii. a polypeptide that has least 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98% or 99% identity to the mature polypeptide sequence of SEQ ID NO: 2; iii. a polypeptide encoded by a nucleic acid that hybridizes under medium stringency, preferably under high stringency conditions to the complementary strand of the mature polypeptide coding sequence of SEQ ID NO:1; iv. a polypeptide encoded by a nucleic acid that has at least 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99% or 100% identity to the mature polypeptide coding sequence of SEQ ID NO: 1.
    Type: Grant
    Filed: April 8, 2016
    Date of Patent: October 29, 2019
    Assignee: DSM IP ASSETS B.V.
    Inventors: Arjen Sein, Rene Marcel De Jong, Evert Tjeerd Van Rij, Willem Bijleveld, Maarten Hotse Wilbrink
  • Publication number: 20190185830
    Abstract: The present invention relates to a polypeptide having lipase activity wherein the polypeptide, which, when aligned with a polypeptide according to SEQ ID NO: 1, comprises at least one amino acid substitution resulting in Ser (S), Ala (A) or Leu (L) at position 246, Trp (W) at position 307, Leu (L) at position 345, Ile (I) at position 365, and/or Phe (F) at position 534, wherein the position is defined with reference to SEQ ID NO: 1, wherein Ala(A) at position 1 in SEQ ID NO: 1 is counted as number 1 and a method for preparing the polypeptide. The present invention further relates to a process for preparing a food product wherein a polypeptide according to the present invention is used.
    Type: Application
    Filed: June 8, 2017
    Publication date: June 20, 2019
    Inventors: Rene Marcel DE JONG, Willem BIJLEVELD, Evert Tjeerd VAN RIJ
  • Publication number: 20180134986
    Abstract: The present invention relates to a polypeptide having phospholipase C activity, selected from the group consisting of i. a polypeptide comprising a mature polypeptide sequence of SEQ ID NO: 2; ii. a polypeptide that has least 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98% or 99% identity to the mature polypeptide sequence of SEQ ID NO: 2; iii. a polypeptide encoded by a nucleic acid that hybridizes under medium stringency, preferably under high stringency conditions to the complementary strand of the mature polypeptide coding sequence of SEQ ID NO:1; iv. a polypeptide encoded by a nucleic acid that has at least 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99% or 100% identity to the mature polypeptide coding sequence of SEQ ID NO: 1.
    Type: Application
    Filed: April 8, 2016
    Publication date: May 17, 2018
    Applicant: DSM IP ASSETS B.V.
    Inventors: Arjen SEIN, Rene Marcel DE JONG, Evert Tjeerd VAN RIJ, Willem BIJLEVELD, Maarten Hotse WILBRINK
  • Publication number: 20120164708
    Abstract: The present invention relates to a composition comprising an enzyme and octanol. Additionally, the present invention relates to a composition comprising a transition metal ion.
    Type: Application
    Filed: June 15, 2010
    Publication date: June 28, 2012
    Inventors: Willem Bijleveld, Rudolf Van Der Pol, Roeland Christiaan Vollinga