Abstract: The present invention relates to pasteurized Akkermansia muciniphila or fragments thereof for treating a metabolic disorder in a subject in need thereof. The present invention also relates to a composition, a pharmaceutical composition and a medicament comprising pasteurized Akkermansia muciniphila or fragments thereof for treating a metabolic disorder. The present invention also relates to the use of pasteurized Akkermansia muciniphila or fragments thereof for promoting weight loss in a subject in need thereof.

Abstract: The present invention relates to a sampling device suitable for in vivo sampling of liquid(s) from the gastro-intestinal tract, comprising a body, the body comprising a channel and an opening for entrance of the liquid(s) at one end of the channel, and a cover bonded to at least part of the body and arranged such that the channel in the body is at least partially covered by the cover, the channel having a length of 2 mm-25 m and a perimeter of 2.4-8600 ?m, the channel further comprising one or more side compartments, and the channel with the optional one or more side compartments having a volume of 5 nl-4500 ?l.

Abstract: Methane can be used as a source for producing hydrogen or hydrogen equivalents in a biological process using mesophilic or thermophilic bacteria of the order of the Thermotogales, e.g. Thermotoga maritima. Hydrogen can be produced as such, or as a reducing equivalent for the reduction of various compounds such as sulphur compounds. Especially, the methane oxidation can be used for anaerobically reducing sulphate to sulphide using methane as the predominant or sole electron donor, in coculture with sulphate-reducing micro-organisms.