Patents by Inventor Willem H. Gispen

Willem H. Gispen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of 1,4-dihydropyridines in diabetes
    Patent number: 5438144
    Abstract: The invention relates to the use of 1,4-dihydropyridines having calcium antagonistic action, in particular of nimodipine, for the preparation of medicaments for controlling damage to peripheral nerves which is caused by diabetes.
    Type: Grant
    Filed: July 9, 1993
    Date of Patent: August 1, 1995
    Assignee: Troponwerke GmbH & Co. KG
    Inventors: Jorg Traber, Willem H. Gispen
  • Peptides with nerve-regenerating properties
    Patent number: 4550099
    Abstract: The present invention relates to the use of the peptides of the general formula:A--B--L--Phe (or L--Ala)--D--Lys--L--Phe--Z--OH, IwhereA represents one of the following groups: H--L--Met, H--L--Met(O), H--L--Met(O.sub.2), desamino-Met, desamino-Met(O) or desamino-Met(O.sub.2),B represents one of the following di-peptide fragments: Glu--His or Ala--Ala, where one amino acid residue of this di-peptide fragment can occur in the D form, andZ is either absent, or represents the amino acid residue Gly, or is the peptide fragment (10-16)--ACTH, where the amino acid L--Lys may be replaced, if desired, by D--Lys at position 11 of the (10-16)--ACTH fragment,and the functional derivatives thereof in promoting axonal regeneration.
    Type: Grant
    Filed: October 9, 1984
    Date of Patent: October 29, 1985
    Assignee: Akzo N.V.
    Inventor: Willem H. Gispen