Patents by Inventor Willem Hendrik Dokter

Willem Hendrik Dokter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7417137
    Abstract: The invention relates to the field of cancer therapy and diagnosis, in particular of carcinomas. The invention provides an isolated and/or recombinant nucleic acid comprising a tissue specific promoter or functional fragment thereof allowing for expression of a nucleic acid of interest operably linked to said promoter or functional fragment thereof in a cancer cell wherein said expression in said cancer cell is essentially carcinoma selective.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: August 26, 2008
    Assignee: Synvolux IP B.V.
    Inventors: Lou Franciscus M. H. de Leij, Marcel Herman J. Ruiters, Pamela Marijke J. McLaughlin, Martin Conrad Harmsen, Henk van der Molen, Peter Terpstra, Willem Hendrik A. Dokter
  • Patent number: 7037475
    Abstract: The invention pertains to precipitated silica particles having edged surfaces and a length: width: depth ratio of 1:1:1 to 3:3–1:1 with the length being 0.25 to 15 mm, an absorbing capacity PV water (wt. % >;125, a pore volume PV Hg (ml/g) 0.8–4, a pore volume PV N2 (ml/g) 0.2–1.5, a bulk density BD (g/l) 200–500, and preferably a pH<8, for use as a cat liter.
    Type: Grant
    Filed: December 14, 2001
    Date of Patent: May 2, 2006
    Assignee: Grace GmbH & Co. KG
    Inventors: Willem Hendrik Dokter, Willem Taede Hulshof, Nicolaas H. M. Leliveld, Jürgen Koltzer
  • Patent number: 6855427
    Abstract: The invention pertains to an amorphous silica particle comprising 0.1 to 105 ppm boron atoms, and optionally 0.05 to 15 wt. % aluminum atoms wherein the boron and aluminum atoms are covalently bonded to the oxygen atoms of the silica network. The amorphous silica particles are used as a reinforcing filler for rubber articles, particularly for tires, more particularly for tire treads.
    Type: Grant
    Filed: February 27, 2001
    Date of Patent: February 15, 2005
    Assignee: Grace GmbH & Co. KG.
    Inventors: Paulus Johannes Kunkeler, Willem Hendrik Dokter
  • Publication number: 20040146444
    Abstract: The invention pertains to precipitated silica particles having edged surfaces and a length: width: depth ratio of 1:1:1 to 3:3-1:1 with the length being 0.25 to 15 mm, an absorbing capacity PV water (wt. % >;125, a pore volume PV Hg (ml/g) 0.8-4, a pore volume PV N2 (ml/g) 0.2-1.5, a bulk density BD (g/l) 200-500, and preferably a pH<8, for use as a cat liter.
    Type: Application
    Filed: February 5, 2004
    Publication date: July 29, 2004
    Inventors: Willem Hendrik Dokter, Willem Taede Hulshof, Nicolaas H.M. Leliveld, Jurgen Koltzer
  • Publication number: 20030159623
    Abstract: The invention pertains to an amorphous silica particle comprising 0.1 to 105 ppm boron atoms, and optionally 0.05 to 15 wt. % aluminum atoms wherein the boron and aluminum atoms are covalently bonded to the oxygen atoms of the silica network. The amorphous silica particles arc used as a reinforcing filler for rubber articles, particularly for tires, more particularly for tire treads.
    Type: Application
    Filed: March 14, 2003
    Publication date: August 28, 2003
    Inventors: Paulus Johannes Kunkeler, Willem Hendrik Dokter
  • Publication number: 20020156041
    Abstract: The invention relates to the field of cancer therapy and diagnosis in particular of carcinomas. The invention provides an isolated and/or recombinant nucleic acid comprising a tissue specific promoter or functional fragment thereof allowing for expression of a nucleic acid of interest operably linked to said promoter or functional fragment thereof in a cancer cell wherein said expression in said cancer cell is essentially carcinoma selective.
    Type: Application
    Filed: March 26, 2002
    Publication date: October 24, 2002
    Inventors: Lou Franciscus M. H. De Leij, Marcel Herman J. Ruiters, Pamela Marijke J. McLaughlin, Martin Conrad Harmsen, Henk Van Der Molen, Peter Terpstra, Willem Hendrik A. Dokter
  • Patent number: 6225280
    Abstract: The present invention relates to a compacted sodium silicate is provided having a molar ratio SiO2:Na2O from 1.6 to 3.3, characterized in that the silicate has the following properties: a bulk density of above 500 g/l, a porosity of above 190 ml/kg, and a mechanical strength corresponding to a dust percentage of below 40 wt %. Also provided is a process for preparing such silicate comprising the steps of: spray-drying an aqueous solution of sodium silicate with a molar ratio SiO2:Na2O from 1.6 to 3.3, applying an outlet temperature above 114° C., applying a water glass solution to the spray-dried powder, subjecting the water glass treated powder to a compacting step, applying a pressure below 100 bar, and crushing the resulting flakes having a thickness of above 4 mm to obtain the compacted sodium silicate.
    Type: Grant
    Filed: May 5, 1998
    Date of Patent: May 1, 2001
    Assignee: Akzo-PQ Silica Vof
    Inventors: Willem Hendrik Dokter, Hubertus Josephus Maria De Koning