Patents by Inventor Willem Jan Bastiaan Van Wamel

Willem Jan Bastiaan Van Wamel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITION AND METHOD FOR TREATING INFECTIONS CAUSED BY VANCOMYCIN-RESISTANT INFECTIOUS AGENTS IN A SUBJECT
    Publication number: 20190000789
    Abstract: The disclosure is related to vancomycin resistance and, in particular, to compositions comprising vancomycin for use in inhibiting growth of a vancomycin-resistant microorganism or for use in treating a subject infected with a vancomycin-resistant pathogen. In one aspect, the disclosure provides a composition comprising vancomycin and d-alanine. The disclosure also provides means and methods for treating a subject infected with a vancomycin-resistant microorganism. The disclosure further provides bacteria with a functionally deactivated gene in the vancomycin-resistance cluster.
    Type: Application
    Filed: December 23, 2016
    Publication date: January 3, 2019
    Inventors: Lizah Tanja van der Aart, Nicole Angelique Lemmens, Willem Jan Bastiaan van Wamel, Gilles Philippus van Wezel
  • Therapeutic Use of LPI, a Staphylococcal Lectin Pathway Inhibitor in Inflammatory Diseases
    Publication number: 20110118194
    Abstract: The invention relates to nucleic acid molecules encoding (poly)peptides having LPI (Lectin Pathway Inhibitor) activity, to recombinant vectors harboring such molecules, and the host cells carrying the vectors. The invention further relates to methods for preparing recombinant (poly)peptides having LPI activity and to the use of such recombinant (poly)peptides having LPI activity for diagnosis, prophylaxis and treatment, such as the treatment of inflammation reactions. In addition the invention provides therapeutic and diagnostic compositions comprising as the active ingredient the (poly)peptide having LPI activity.
    Type: Application
    Filed: November 4, 2010
    Publication date: May 19, 2011
    Applicant: UMC Utrecht Holding B.V.
    Inventors: Willem Jan Bastiaan VAN WAMEL, Suzan Huberdian Maria Rooijakkers, Cornelis Petrus Maria Van Kessel, Johannes Antonius Gerardus Van Strijp
  • THERAPEUTIC USE OF SCIN, A STAPHYLOCOCCAL COMPLEMENT INHIBITOR IN INFLAMMATORY DISEASES
    Publication number: 20090246175
    Abstract: The present invention relates to the use of the staphylococcal complement inhibitor (SCIN) or a homologue thereof, or a derivative or a fragment of SCIN or the SCIN homologue for the preparation of a medicament for intervening with C3 and C5 convertases. The medicament is in particular intended for inhibiting activation of the classical and/or the alternative pathway of complement. More in particular, the medicament is for treating indications that involve complement activation via the classical and/or alternative pathway.
    Type: Application
    Filed: April 3, 2006
    Publication date: October 1, 2009
    Applicant: UMC Utrecht Holding B.V.
    Inventors: Suzan H. M. Rooijakkers, Willem Jan Bastiaan Van Wamel, Cornelis P. M. Van Kessel, Johannes A. G. Van Strijp
  • Therapeutic Use of Lpi, a Staphylococcal Lectin Pathway Inhibitor in Inflammatory diseases
    Publication number: 20090202437
    Abstract: The invention relates to nucleic acid molecules encoding (poly)peptides having LPI (Lectin Pathway Inhibitor) activity, to recombinant vectors harboring such molecules, and the host cells carrying the vectors. The invention further relates to methods for preparing recombinant (poly)peptides having LPI activity and to the use of such recombinant (poly)peptides having LPI activity for diagnosis, prophylaxis and treatment, such as the treatment of inflammation reactions. In addition the invention provides therapeutic and diagnostic compositions comprising as the active ingredient the (poly)peptide having LPI activity.
    Type: Application
    Filed: July 8, 2004
    Publication date: August 13, 2009
    Inventors: Willem Jan Bastiaan Van Wamel, Suzan Huberdina Maria Rooijakkers, Cornelis Petrus Maria Van Kessel, Johannes Antonius Gerardus Van Strijp