Patents by Inventor Willem LIGTENBERG

Willem LIGTENBERG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IBRUTINIB COMBINATION THERAPY
    Publication number: 20200368235
    Abstract: Combinations of Bruton's tyrosine kinase (Btk) inhibitors, e.g., 1-((R)-3-(4-amino-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, with a second anticancer agent are provided. Also provided are methods of treating cancers, and autoimmune disorders by administering combinations of Bruton's tyrosine kinase (Btk) inhibitors, e.g., 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, and second anticancer agents.
    Type: Application
    Filed: August 1, 2019
    Publication date: November 26, 2020
    Inventors: Betty Chang, Sriram Balasubramanian, Richard Crowley, Hsu-Ping Kuo, Brett Hall, Kate A. Sasser, Tineke Casneuf, Michael Schaffer, Matthias Versele, Willem Ligtenberg, Cue Davis
  • IBRUTINIB COMBINATION THERAPY
    Publication number: 20160287592
    Abstract: Combinations of Bruton's tyrosine kinase (Btk) inhibitors, e.g., 1-((R)-3-(4-amino-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, with a second anticancer agent are provided. Also provided are methods of treating cancers, and autoimmune disorders by administering combinations of Bruton's tyrosine kinase (Btk) inhibitors, e.g., 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, and second anticancer agents.
    Type: Application
    Filed: April 8, 2014
    Publication date: October 6, 2016
    Inventors: Betty CHANG, Sriram BALASUBRAMANIAN, Richard CROWLEY, Hsu-Ping KUO, Brett HALL, Kate A. SASSER, Tineke CASNEUF, Michael SHAFFER, Matthias VERSELE, Willem LIGTENBERG, Cuc DAVIS