Patents by Inventor Willem Luytjes

Willem Luytjes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Respiratory syncytial virus with a genomic deficiency complemented in trans
    Patent number: 10967014
    Abstract: The invention relates to pneumoviral virions comprising a viral genome that has a mutation in a gene coding for a protein that is essential for infectivity of the pneumovirus, whereby the mutation causes a virus produced from only the viral genome to lack infectivity, and whereby the virion comprises the protein in a form and in an amount that is required for infectivity of the virion. The invention also relates to methods for producing the pneumoviral virions and for using the virions in the treatment or prevention of pneumoviral infection and disease. A preferred pneumoviral virion is a virion of Respiratory Syncytial Virus in which preferably the gene for the G attachment protein is inactivated and complemented in trans.
    Type: Grant
    Filed: January 9, 2018
    Date of Patent: April 6, 2021
    Assignee: De Staat der Nederlanden, vert. door de minister van VWS
    Inventors: Willem Luytjes, Myra Noorely Widjojoatmodjo
  • RESPIRATORY SYNCYTIAL VIRUS WITH A GENOMIC DEFICIENCY COMPLEMENTED IN TRANS
    Publication number: 20180207211
    Abstract: The invention relates to pneumoviral virions comprising a viral genome that has a mutation in a gene coding for a protein that is essential for infectivity of the pneumovirus, whereby the mutation causes a virus produced from only the viral genome to lack infectivity, and whereby the virion comprises the protein in a form and in an amount that is required for infectivity of the virion. The invention also relates to methods for producing the pneumoviral virions and for using the virions in the treatment or prevention of pneumoviral infection and disease. A preferred pneumoviral virion is a virion of Respiratory Syncytial Virus in which preferably the gene for the G attachment protein is inactivated and complemented in trans.
    Type: Application
    Filed: January 9, 2018
    Publication date: July 26, 2018
    Applicant: De Staat der Nederlanden, vert. door de minister van VWS
    Inventors: Willem LUYTJES, Myra Noorely WIDJOJOATMODJO
  • Respiratory syncytial virus with a genomic deficiency complemented in trans
    Patent number: 9889168
    Abstract: The invention relates to pneumoviral virions comprising a viral genome that has a mutation in a gene coding for a protein that is essential for infectivity of the pneumovirus, whereby the mutation causes a virus produced from only the viral genome to lack infectivity, and whereby the virion comprises the protein in a form and in an amount that is required for infectivity of the virion. The invention also relates to methods for producing the pneumoviral virions and for using the virions in the treatment or prevention of pneumoviral infection and disease. A preferred pneumoviral virion is a virion of Respiratory Syncytial Virus in which preferably the gene for the G attachment protein is inactivated and complemented in trans.
    Type: Grant
    Filed: July 31, 2015
    Date of Patent: February 13, 2018
    Assignee: De Staat der Nederlanden, vert, door de minister van VWS
    Inventors: Willem Luytjes, Myra Noorely Widjojoatmodjo
  • RESPIRATORY SYNCYTIAL VIRUS WITH A GENOMIC DEFICIENCY COMPLEMENTED IN TRANS
    Publication number: 20150329833
    Abstract: The invention relates to pneumoviral virions comprising a viral genome that has a mutation in a gene coding for a protein that is essential for infectivity of the pneumovirus, whereby the mutation causes a virus produced from only the viral genome to lack infectivity, and whereby the virion comprises the protein in a form and in an amount that is required for infectivity of the virion. The invention also relates to methods for producing the pneumoviral virions and for using the virions in the treatment or prevention of pneumoviral infection and disease. A preferred pneumoviral virion is a virion of Respiratory Syncytial Virus in which preferably the gene for the G attachment protein is inactivated and complemented in trans.
    Type: Application
    Filed: July 31, 2015
    Publication date: November 19, 2015
    Applicant: De Staat der Nederlanden, vert. door de minister van VWS
    Inventors: Willem LUYTJES, Myra Noorely WIDJOJOATMODJO
  • Respiratory syncytial virus with a genomic deficiency complemented in trans
    Patent number: 9107939
    Abstract: The invention relates to pneumoviral virions comprising a viral genome that has a mutation in a gene coding for a protein that is essential for infectivity of the pneumovirus, whereby the mutation causes a virus produced from only the viral genome to lack infectivity, and whereby the virion comprises the protein in a form and in an amount that is required for infectivity of the virion. The invention also relates to methods for producing the pneumoviral virions and for using the virions in the treatment or prevention of pneumoviral infection and disease. A preferred pneumoviral virion is a virion of Respiratory Syncytial Virus in which preferably the gene for the G attachment protein is inactivated and complemented in trans.
    Type: Grant
    Filed: December 24, 2004
    Date of Patent: August 18, 2015
    Assignee: De Staat der Nederlanden, Vert. Door de Minister Van VWS
    Inventors: Willem Luytjes, Myra Noorely Widjojoatmodjo
  • Respiratory syncytial virus with a genomic deficiency complemented in trans
    Publication number: 20100291035
    Abstract: The invention relates to pneumoviral virions comprising a viral genome that has a mutation in a gene coding for a protein that is essential for infectivity of the pneumovirus, whereby the mutation causes a virus produced from only the viral genome to lack infectivity, and whereby the virion comprises the protein in a form and in an amount that is required for infectivity of the virion. The invention also relates to methods for producing the pneumoviral virions and for using the virions in the treatment or prevention of pneumoviral infection and disease. A preferred pneumoviral virion is a virion of Respiratory Syncytial Virus in which preferably the gene for the G attachment protein is inactivated and complemented in trans.
    Type: Application
    Filed: December 24, 2004
    Publication date: November 18, 2010
    Applicant: DE Staat Der Nederlanden, Vertegenwoordigd Door de Minister Van Volksgezondheil, Welzijn en Sprot
    Inventors: Willem Luytjes, Myra Noorely Widjojoatmodjo