Patents by Inventor Willem Raaben

Willem Raaben has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chimeric alkaline phosphatase-like proteins
    Patent number: 11746340
    Abstract: The invention relates to improved alkaline phosphatases, pharmaceutical compositions comprising improved alkaline phosphatases and the use of improved alkaline phosphatases for preventing, treating or curing diseases.
    Type: Grant
    Filed: October 16, 2020
    Date of Patent: September 5, 2023
    Assignee: AM-PHARMA B.V.
    Inventors: Willem Raaben, Luigi Johannes Cornelius Jonk, Erik Jan Van Den Berg, Andrea Van Elsas, José Luis Millán
  • CHIMERIC ALKALINE PHOSPHATASE-LIKE PROTEINS
    Publication number: 20210163905
    Abstract: The invention relates to improved alkaline phosphatases, pharmaceutical compositions comprising improved alkaline phosphatases and the use of improved alkaline phosphatases for preventing, treating or curing diseases.
    Type: Application
    Filed: October 16, 2020
    Publication date: June 3, 2021
    Inventors: Willem RAABEN, Luigi Johannes Cornelius Jonk, Erik Jan Van Den Berg, Andrea Van Elsas, José Luis MILLÁN
  • Chimeric alkaline phosphatase-like proteins
    Patent number: 10822597
    Abstract: The invention relates to improved alkaline phosphatases, pharmaceutical compositions comprising improved alkaline phosphatases and the use of improved alkaline phosphatases for preventing, treating or curing diseases.
    Type: Grant
    Filed: February 7, 2018
    Date of Patent: November 3, 2020
    Assignee: AM-Pharma B.V.
    Inventors: Willem Raaben, Luigi Johannes Cornelius Jonk, Erik Jan Van Den Berg, Andrea Van Elsas, José Luis Millán
  • USE OF ALKALINE PHOSPHATASE FOR PRESERVING RENAL FUNCTION
    Publication number: 20190209662
    Abstract: The invention relates to the field of medicine and in particular to means and methods for preserving renal function after a treatment with a risk of reducing renal function. The present invention also relates to means and methods for shortening the duration of renal replacement therapy, increasing the creatinine clearance and decreasing the adverse effects of medicaments.
    Type: Application
    Filed: September 10, 2018
    Publication date: July 11, 2019
    Inventors: Jacques Salomon Robert Arend, Erik Jan Van Den Berg, Willem Raaben
  • Chimeric Alkaline Phosphatase-Like Proteins
    Publication number: 20190024062
    Abstract: The invention relates to improved alkaline phosphatases, pharmaceutical compositions comprising improved alkaline phosphatases and the use of improved alkaline phosphatases for preventing, treating or curing diseases.
    Type: Application
    Filed: February 7, 2018
    Publication date: January 24, 2019
    Applicant: AM-Pharma B.V.
    Inventors: Willem RAABEN, Luigi Johannes Cornelius JONK, Erik Jan VAN DEN BERG, Andrea VAN ELSAS, José Luis MILLÁN
  • Chimeric alkaline phosphatase-like proteins
    Patent number: 9926544
    Abstract: The invention relates to improved alkaline phosphatases, pharmaceutical compositions comprising improved alkaline phosphatases and the use of improved alkaline phosphatases for preventing, treating or curing diseases.
    Type: Grant
    Filed: January 26, 2015
    Date of Patent: March 27, 2018
    Assignee: AM-Pharma B.V.
    Inventors: Willem Raaben, Luigi Johannes Cornelius Jonk, Erik Jan Van Den Berg, Andrea Van Elsas, José Luis Millán
  • Chimeric Alkaline Phosphatase-Like Proteins
    Publication number: 20170009216
    Abstract: The invention relates to improved alkaline phosphatases, pharmaceutical compositions comprising improved alkaline phosphatases and the use of improved alkaline phosphatases for preventing, treating or curing diseases.
    Type: Application
    Filed: January 26, 2015
    Publication date: January 12, 2017
    Applicant: AM-Pharma B.V.
    Inventors: Willem RAABEN, Luigi Johannes Cornelius JONK, Erik Jan VAN DEN BERG, Andrea VAN ELSAS, José Luis MILLÁN
  • Use of Alkaline Phosphatase for Preserving Renal Function
    Publication number: 20160250299
    Abstract: The invention relates to the field of medicine and in particular to means and methods for preserving renal function after a treatment with a risk of reducing renal function. The present invention also relates to means and methods for shortening the duration of renal replacement therapy, increasing the creatinine clearance and decreasing the adverse effects of medicaments.
    Type: Application
    Filed: January 28, 2016
    Publication date: September 1, 2016
    Inventors: Jacques Salomon Robert AREND, Erik Jan Van Den Berg, Willem Raaben
  • Modified Phosphatases
    Publication number: 20160046913
    Abstract: The invention relates to phosphatases and more in specific to (genetically) modified phosphatases, pharmaceutical compositions comprising (genetically) modified phosphatases and the use of (genetically) modified phosphatases for treating or curing for example sepsis, inflammatory bowel disease or other inflammatory diseases, or renal failure. The invention further relates to a method for producing phosphatases.
    Type: Application
    Filed: March 23, 2015
    Publication date: February 18, 2016
    Applicant: AM-PHARMA B.V.
    Inventors: Markwin Paul VELDERS, Luigi Johannes Cornelius JONK, Willem RAABEN, Marty Bernardus Fransiscus WULFERINK
  • The Use of Alkaline Phosphatase for Preserving Renal Function
    Publication number: 20140219984
    Abstract: The invention relates to the field of medicine and in particular to means and methods for preserving renal function after a treatment with a risk of reducing renal function. The present invention also relates to means and methods for shortening the duration of renal replacement therapy, increasing the creatinine clearance and decreasing the adverse effects of medicaments.
    Type: Application
    Filed: June 8, 2012
    Publication date: August 7, 2014
    Applicant: AM-PHARMA B.V.
    Inventors: Jacques Salomon Robert Arend, Erik Jan Van Den Berg, Willem Raaben
  • Modified Phosphatases
    Publication number: 20140193388
    Abstract: The invention relates to phosphatases and more in specific to (genetically) modified phosphatases, pharmaceutical compositions comprising (genetically) modified phosphatases and the use of (genetically) modified phosphatases for treating or curing for example sepsis, inflammatory bowel disease or other inflammatory diseases, or renal failure. The invention further relates to a method for producing phosphatases.
    Type: Application
    Filed: September 6, 2013
    Publication date: July 10, 2014
    Applicant: AM-PHARMA B.V.
    Inventors: MARKWIN PAUL VELDERS, LUIGI JOHANNES CORNELIUS JONK, WILLEM RAABEN, MARTY BERNARDUS FRANSISCUS WULFERINK
  • Use of alkaline phosphatase in the treatment of reduced renal function
    Patent number: 8586032
    Abstract: The invention relates to the field of medicine and in particular to the use of alkaline phosphatase in the treatment of renal diseases, such as reduced renal function. The present invention also relates to the field of pharmacy and in particular to the pharmaceutical use of alkaline phosphatase. The present invention provides an alternative treatment to improve a situation in which the renal function is reduced by using alkaline phosphatase.
    Type: Grant
    Filed: January 30, 2008
    Date of Patent: November 19, 2013
    Assignee: AM-Pharma B.V.
    Inventors: Roelof P. Pickkers, Suzanne Heemskerk, Markwin P. Velders, Willem Raaben, Marty B. F. Wulferink
  • Modified phosphatases
    Patent number: 8557545
    Abstract: The invention relates to phosphatases and more in specific to (genetically) modified phosphatases, pharmaceutical compositions comprising (genetically) modified phosphatases and the use of (genetically) modified phosphatases for treating or curing for example sepsis, inflammatory bowel disease or other inflammatory diseases, or renal failure. The invention further relates to a method for producing phosphatases.
    Type: Grant
    Filed: April 25, 2008
    Date of Patent: October 15, 2013
    Assignee: Am-Pharma B.V.
    Inventors: Markwin Paul Velders, Luigi Johannes Cornelius Jonk, Willem Raaben, Marty Bernardus Fransiscus Wulferink
  • MODIFIED PHOSPHATASES
    Publication number: 20100143323
    Abstract: The invention relates to phosphatases and more in specific to (genetically) modified phosphatases, pharmaceutical compositions comprising (genetically) modified phosphatases and the use of (genetically) modified phosphatases for treating or curing for example sepsis, inflammatory bowel disease or other inflammatory diseases, or renal failure. The invention further relates to a method for producing phosphatases.
    Type: Application
    Filed: April 25, 2008
    Publication date: June 10, 2010
    Inventors: Markwin Paul Velders, Luigi Johannes Cornelius Jonk, Willem Raaben, Marty Bernardus Fransiscus Wulferink
  • USE OF ALKALINE PHOSPHATASE IN THE TREATMENT OF REDUCED RENAL FUNCTION
    Publication number: 20100111923
    Abstract: The invention relates to the field of medicine and in particular to the use of alkaline phosphatase in the treatment of renal diseases, such as reduced renal function. The present invention also relates to the field of pharmacy and in particular to the pharmaceutical use of alkaline phosphatase. The present invention provides an alternative treatment to improve a situation in which the renal function is reduced by using alkaline phosphatase.
    Type: Application
    Filed: January 30, 2008
    Publication date: May 6, 2010
    Inventors: Roelof P. Pickkers, Suzanne Heemskerk, Markwin P. Velders, Willem Raaben, Marty B.F. Wulferink