Patents by Inventor Willem Roskam

Willem Roskam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Drugs containing a glycosylated interleukin-2
    Patent number: 5417970
    Abstract: An interleukin-2 preparation suitable for pharmaceutical purposes, consisting essentially of disialilated glycosylated interleukin-2, monosialilated glycosylated interleukin-2, or a mixture thereof, and substantially free of organic solvents, is isolated from recombinant CHO cells transformed with a vector containing a DNA sequence coding for a natural precursor of human interleukin-2, and is purified by a multi-step process.
    Type: Grant
    Filed: November 16, 1993
    Date of Patent: May 23, 1995
    Assignee: Sanofi
    Inventors: Willem Roskam, deceased, Bertrand Basuyaux, Pascual Ferrara, Martine Laporte, Thierry Maureaud, Natalio Vita, Alain Bayol, Genevieve Perry
  • Microbiological process for the preparation of a protein by culturing a mutant bacterial strain
    Patent number: 4945047
    Abstract: The invention relates to a microbiological process for the preparation of a protein by culturing a mutant bacterial strain.This process consists in using a bacterial strain carrying a mutation which limits, or even suppresses, the expression of the operons whose transcription depends on the fixation of the cAMP-CRP complex, a DNA sequence coding for a protein precursor having been introduced into the said bacterial strain.
    Type: Grant
    Filed: April 9, 1987
    Date of Patent: July 31, 1990
    Assignee: Societe Anonyme: Sanofi
    Inventors: Richard Legoux, Pascal Leplatois, Evelyne L. Joseph, Brigitte Niaudet, Willem Roskam