Patents by Inventor William A. Brady

William A. Brady has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240397637
    Abstract: A housing assembly for electronics, the assembly including a rigid base member for mounting at least one printed circuit board thereto, a rigid outer shell, and a flexible inner sealing membrane, the base member and the outer shell together forming an enclosure for the at least one printed circuit board. The flexible membrane includes a sealing portion about its periphery for compression between the base member and the outer shell to seal the enclosure, and also includes a plurality of inwardly projecting, elastically deformable abutments configured to compress against the at least one printed circuit board to provide vibration resistance.
    Type: Application
    Filed: August 5, 2022
    Publication date: November 28, 2024
    Inventors: Peter William Cosgriff, Seth Michael Brady
  • Patent number: 12128013
    Abstract: The present invention provides for the treatment, prevention, and/or reduction of a risk of a disease, disorder, or condition in which aldehyde toxicity is implicated in the pathogenesis, including ocular disorders, skin disorders, conditions associated with injurious effects from blister agents, and autoimmune, inflammatory, neurological and cardiovascular diseases by the use of a primary amine to scavenge toxic aldehydes, such as MDA and HNE.
    Type: Grant
    Filed: August 22, 2023
    Date of Patent: October 29, 2024
    Assignee: Aldeyra Therapeutics, Inc.
    Inventors: Todd Brady, Scott Young, William A. Kinney, Kenneth J. Mandell
  • Publication number: 20240350835
    Abstract: The invention relates to prostate specific membrane antigen antibodies (anti-PSMA) and anti-PSMA antibody drug conjugates. The invention also relates to methods and compositions for using anti-PSMA antibody drug conjugates in inhibiting, preventing or treating PSMA related diseases or cancers.
    Type: Application
    Filed: July 1, 2024
    Publication date: October 24, 2024
    Applicant: Ambrx, Inc.
    Inventors: Shivarupam BHOWMIK, Jianing WANG, Jinming XIA, William BRADY, Feng TIAN
  • Publication number: 20240283033
    Abstract: A method for testing a battery component for leakage includes generating a sample from a battery component storing electrolyte using a Fourier Transform infrared (FT-IR) spectrometer, comparing absorbance levels of the sample at N predetermined frequencies to N predetermined thresholds, respectively, where N is an integer greater than one; and selectively detecting at least one of an electrolyte leak and generating an electrolyte concentration estimate in response to the comparison. The battery component is selected from a group consisting of a battery cell, a battery module, and a battery pack.
    Type: Application
    Filed: February 22, 2023
    Publication date: August 22, 2024
    Inventors: Ryan Curtis SEKOL, James R. SALVADOR, Michelle H. WIEBENGA, William Reginald COLLIN, Christopher BRADY, Robert H. DIETZE, JR., Jennifer Therese BRACEY, Houssen YANG
  • Patent number: 12059473
    Abstract: The invention relates to prostate specific membrane antigen humanized antibodies (anti-PSMA) and anti-PSMA antibody drug conjugates. The invention also relates to methods and compositions for using anti-PSMA antibody drug conjugates in inhibiting, preventing or treating PSMA related diseases or cancers.
    Type: Grant
    Filed: March 29, 2019
    Date of Patent: August 13, 2024
    Assignee: Ambrx, Inc.
    Inventors: Shivarupam Bhowmik, Jianing Wang, Jinming Xia, William Brady, Feng Tian
  • Patent number: 11636162
    Abstract: A document review system is configured to quickly provide search results for large amounts of documents. Ontology templates are used to generate objects and links based on the documents. Users can view documents, and linked objects and object properties can be displayed. An index assisted search can be performed to determine the linked objects and object properties. A supplemental search can be performed on a second database that tracks modifications to the documents or objects. The modifications in the second database can be periodically written to the first database, and the index can be rebuilt. The user experience can be free of slow searches and slow index rebuilds.
    Type: Grant
    Filed: November 16, 2021
    Date of Patent: April 25, 2023
    Assignee: Palantir Technologies Inc.
    Inventors: Eric Schwartz, Alexander Bores, Alexander Martino, Brendan Berg, Charles Sharzer, Doron Shapiro, Enoch Hsiao, Eric Knudson, Landon Bell, Martin Manville, Michael Platek, Nathan Bruner, Robert Giardina, Sarah Beckoff, Tri Tang, William Brady, Wenshuai Hou
  • Publication number: 20220292250
    Abstract: A computer-implemented method is provided to provide analysis of claim information. The system may receive claim data from a plurality of entities and, for one or more claim items in the received claim data, determine a format of the claim item. The system may convert the claim item from the determined format into a standard format. The system may receive a selection of one or more providers, and determine one or more claim items associated with the provider in the selection. The system may generate a user interface, the user interface comprising a visual representation of one or more attributes of the one or more claim items.
    Type: Application
    Filed: February 25, 2022
    Publication date: September 15, 2022
    Inventors: Charles Sharzer, Meghana Bhat, William Brady
  • Publication number: 20220147576
    Abstract: A document review system is configured to quickly provide search results for large amounts of documents. Ontology templates are used to generate objects and links based on the documents. Users can view documents, and linked objects and object properties can be displayed. An index assisted search can be performed to determine the linked objects and object properties. A supplemental search can be performed on a second database that tracks modifications to the documents or objects. The modifications in the second database can be periodically written to the first database, and the index can be rebuilt. The user experience can be free of slow searches and slow index rebuilds.
    Type: Application
    Filed: November 16, 2021
    Publication date: May 12, 2022
    Inventors: Eric Schwartz, Alexander Bores, Alexander Martino, Brendan Berg, Charles Sharzer, Doron Shapiro, Enoch Hsiao, Eric Knudson, Landon Bell, Martin Manville, Michael Platek, Nathan Bruner, Robert Giardina, Sarah Beckoff, Tri Tang, William Brady, Wenshuai Hou
  • Publication number: 20220089768
    Abstract: Disclosed herein are multi-specific binding polypeptide molecules (e.g., multi-specific antibodies) that can interact with a tumor cell and an immunosuppressive cell. In some embodiments, also described herein are methods for treating one or more diseases or conditions (e.g., cancers) using the multi-specific binding polypeptides (e.g., multi-specific antibodies).
    Type: Application
    Filed: January 3, 2020
    Publication date: March 24, 2022
    Inventors: Shivarupam BHOWMIK, William A. BRADY
  • Patent number: 11263382
    Abstract: A computer-implemented method is provided to provide analysis of claim information. The system may receive claim data from a plurality of entities and, for one or more claim items in the received claim data, determine a format of the claim item. The system may convert the claim item from the determined format into a standard format. The system may receive a selection of one or more providers, and determine one or more claim items associated with the provider in the selection. The system may generate a user interface, the user interface comprising a visual representation of one or more attributes of the one or more claim items.
    Type: Grant
    Filed: January 17, 2018
    Date of Patent: March 1, 2022
    Assignee: Palantir Technologies Inc.
    Inventors: Charles Sharzer, Meghana Bhat, William Brady
  • Patent number: 11210349
    Abstract: A document review system is configured to quickly provide search results for large amounts of documents. Ontology templates are used to generate objects and links based on the documents. Users can view documents, and linked objects and object properties can be displayed. An index assisted search can be performed to determine the linked objects and object properties. A supplemental search can be performed on a second database that tracks modifications to the documents or objects. The modifications in the second database can be periodically written to the first database, and the index can be rebuilt. The user experience can be free of slow searches and slow index rebuilds.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: December 28, 2021
    Assignee: Palantir Technologies Inc.
    Inventors: Eric Schwartz, Alexander Bores, Alexander Martino, Brendan Berg, Charles Sharzer, Doron Shapiro, Enoch Hsiao, Eric Knudson, Landon Bell, Martin Manville, Michael Platek, Nathan Bruner, Robert Giardina, Sarah Beckoff, Tri Tang, William Brady, Wenshuai Hou
  • Publication number: 20210015940
    Abstract: The invention relates to prostate specific membrane antigen humanized antibodies (anti-PSMA) and anti-PSMA antibody drug conjugates. The invention also relates to methods and compositions for using anti-PSMA antibody drug conjugates in inhibiting, preventing or treating PSMA related diseases or cancers.
    Type: Application
    Filed: March 29, 2019
    Publication date: January 21, 2021
    Applicant: Ambrx, Inc.
    Inventors: Shivarupam Bhowmik, Jianing Wang, Jinming Xia, William Brady, Feng Tian
  • Publication number: 20200354447
    Abstract: Multivalent binding peptides, including bi-specific binding peptides, having immunoglobulin effector function are provided, along with encoding nucleic acids, vectors and host cells as well as methods for making such peptides and methods for using such peptides to treat or prevent a variety of diseases, disorders or conditions, as well as to ameliorate at least one symptom associated with such a disease, disorder or condition.
    Type: Application
    Filed: December 23, 2019
    Publication date: November 12, 2020
    Inventors: Peter Armstrong THOMPSON, Jeffrey A. LEDBETTER, Martha Susan HAYDEN-LEDBETTER, Laura Sue GROSMAIRE, Robert BADER, William BRADY
  • Patent number: 10678061
    Abstract: An optical system and method that utilize multiple low-etendue lasers to illuminate multiple spots one or more spatial light modulators. Stereoscopic systems may be formed by using different wavelengths or different polarizations for each spot. Light from each spot is guided to each eye of the viewer by wearing 3D glasses.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: June 9, 2020
    Assignee: Laser Light Engines, Inc.
    Inventor: William Brady Beck
  • Patent number: 10604327
    Abstract: A removably attachable insulator having a jacket adapted to slide over a container for keeping the contents of the container at or near a predetermined temperature is provided. The jacket may include heating elements attached thereto for heating the container. A control circuitry is also integrated with the jacket, the control circuitry providing a thermostat adapted to set and control the temperature through operatively associating with the heating elements. The jacket and container may become removably attached through the use of detachable fasteners integrated with the container and or the jacket.
    Type: Grant
    Filed: March 9, 2018
    Date of Patent: March 31, 2020
    Inventor: Robert William Brady, Jr.
  • Publication number: 20190364036
    Abstract: The present disclosure generally relates systems, apparatus, and methods for security devices, in particular, low-power, security devices and other devices. The devices typically connect to the Internet or other networks only on an intermittent, event-based basis, typically by cellular modem. The invention meets a need for security devices, as well as other devices, that can connect to the Internet and other networks but that are low-power and/or intermittently connected to networks such as the Internet on an intermittent and/or on demand basis. This renders them more secure, less susceptible to hacking and other attacks, less prone to continuously gathering data that a user might consider to be superfluous and/or invasive in terms of data collected, and can make them low-power, thus allowing them to run on battery for long periods of time.
    Type: Application
    Filed: May 22, 2019
    Publication date: November 28, 2019
    Applicant: Simtek, Inc.
    Inventors: William Brady Simpson, Ari Chivukula, Norman Scott Storkel, Steven Shenker, Eric Shrewsberry, Phang Moh Lim, John O'Leary
  • Publication number: 20190290755
    Abstract: The present invention generally provides methods for B-cell reduction in an individual using CD37-specific binding molecules. In particular, the invention provides methods for B-cell reduction using CD37-specific binding molecules alone, or a combination of CD37-specific binding molecules and CD20-specific binding molecules, in some instances a synergistic combination. The invention further provides materials and methods for treatment of diseases involving aberrant B-cell activity. In addition; the invention provides humanized CD37-specific binding molecules.
    Type: Application
    Filed: October 26, 2018
    Publication date: September 26, 2019
    Inventors: Laura Sue Grosmaire, Martha Susan Hayden-Ledbetter, Jeffrey A. Ledbetter, Peter Armstrong Thompson, Sandy Alexander Simon, William Brady
  • Publication number: 20190276220
    Abstract: A removably attachable insulator having a jacket adapted to slide over a container for keeping the contents of the container at or near a predetermined temperature is provided. The jacket may include heating elements attached thereto for heating the container. A control circuitry is also integrated with the jacket, the control circuitry providing a thermostat adapted to set and control the temperature through operatively associating with the heating elements. The jacket and container may become removably attached through the use of detachable fasteners integrated with the container and or the jacket.
    Type: Application
    Filed: March 9, 2018
    Publication date: September 12, 2019
    Inventor: Robert William Brady, JR.
  • Patent number: 10307481
    Abstract: The present invention generally provides methods for B-cell reduction in an individual using CD37-specific binding molecules. In particular, the invention provides methods for B-cell reduction using CD37-specific binding molecules alone, or a combination of CD37-specific binding molecules and CD20-specific binding molecules, in some instances a synergistic combination. The invention further provides materials and methods for treatment of diseases involving aberrant B-cell activity. In addition, the invention provides humanized CD37-specific binding molecules.
    Type: Grant
    Filed: July 25, 2006
    Date of Patent: June 4, 2019
    Assignee: Aptevo Research and Development LLC
    Inventors: Laura S. Grosmaire, Martha S. Hayden-Ledbetter, Jeffrey A. Ledbetter, Peter A. Thompson, Sandy A. Simon, William Brady
  • Patent number: 10253345
    Abstract: There is provided inter alia a process for stabilizing a eukaryotic cell line which expresses PylRS and tRNAPyl and which is suitable for incorporation of a gene encoding a target protein containing one or more non-natural amino acids encoded by a nonsense codon which comprises culturing said cell line under conditions in which the adverse effect of tRNAPyl expression on cell viability and/or cell growth is reduced or eliminated.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: April 9, 2019
    Assignee: MEDIMMUNE LIMITED
    Inventors: Kenneth H. Grabstein, Michael Van Brunt, Marcello Marelli, William Brady, Jeffrey C. Johnson