Abstract: Embodiments are for processor cross-core cache line contention management. A computer-implemented method includes sending a cross-invalidate command to one or more caches based on receiving a cache state change request for a cache line in a symmetric multiprocessing system and determining a retry delay based on receiving a cross-invalidate reject response from at least one of the one or more caches. The computer-implemented method also includes waiting until a retry delay period associated with the retry delay has elapsed to resend the cross-invalidate command to the one or more caches and granting the cache state change request for the cache line based on receiving a cross-invalidate accept response from the one or more caches.

Abstract: The subject application provides small compounds that are able to suppress autophagy in various cells. These compounds are useful in augmenting the existing treatments of various cancers and microbial/parasitic infections. Thus, the subject application also provides methods of treating various types of cancers and microbial/parasitic infections. Also provided by the subject application are methods of suppressing the expansion of autophagosomes within cells or individuals and inhibiting the lipidation of autophagy-related protein 8 (Atg8).