Abstract: A reciprocating piston pump may include a fluid handling portion comprising a fluid inlet, a fluid outlet, and a pump chamber; a drive assembly portion comprising a piston drive assembly, a reciprocating piston, a drive assembly housing, and a drive assembly chamber; and an electro-fluidic leak detection element comprising a fluid sensing portion. The reciprocating piston of the drive assembly portion extends into the pump chamber of the fluid handling portion. The piston drive assembly operates to reciprocate the reciprocating piston within the pump chamber. The electro-fluidic leak detection element is mounted within the drive assembly portion. The electro-fluidic leak detection element is configured to generate a fluid leakage signal when fluid from the pump chamber enters the drive assembly chamber and contacts the fluid sensing portion of the electro-fluidic leak detection element. A plurality of reciprocating piston pumps may be incorporated into fluid handling systems.

Abstract: A pinch valve configuration may include a pinch valve comprising a valve body, a valve plunger, and a fluidic tubing pinch passage defined between a tubing seat of the valve body and an operative end of the valve plunger. The pinch valve configuration may further include a Hall effect sensor assembly comprising a stationary element anchored to the valve body and a motive element anchored to the valve plunger. The pinch valve configuration additionally includes a failure prediction module in communication with the Hall effect sensor assembly. The failure prediction module is programmed to process an output signal of the Hall effect sensor assembly as a displacement reading, to compare the displacement reading with a failure prediction threshold, and to generate a failure prediction signal from the comparison of the displacement reading with the failure prediction threshold.

Abstract: A medication delivery device, particularly an intradermal delivery device, having a needle cannula, with a sharpened distal end having a forward tip, and a limiter disposed about the needle cannula. The limiter has a distal end defining a skin engaging surface which is disposed transversely to, and at least partially about, the needle cannula. The skin engaging surface is generally non-flat with generally coplanar portions, and a recess being defined in the skin engaging surface which defines a void in or adjacent to the coplanar portions into which portions of a patient's skin can be deformed into when the skin engaging surface is pressed against the patient's skin. The forward tip of the needle cannula is spaced apart from a plane defined by the coplanar portions a distance ranging from about 0.5 mm to 3.0 mm such that the skin engaging surface limits penetration of the forward tip of the needle cannula to the dermis layer of the patient's skin.

Abstract: A medication delivery device, particularly an intradermal delivery device, having a needle cannula, with a sharpened distal end having a forward tip, and a limiter disposed about the needle cannula. The limiter has a distal end defining a skin engaging surface which is disposed transversely to, and at least partially about, the needle cannula. The skin engaging surface is generally non-flat with generally coplanar portions, and a recess being defined in the skin engaging surface which defines a void in or adjacent to the coplanar portions into which portions of a patient's skin can be deformed into when the skin engaging surface is pressed against the patient's skin. The forward tip of the needle cannula is spaced apart from a plane defined by the coplanar portions a distance ranging from about 0.5 mm to 3.0 mm such that the skin engaging surface limits penetration of the forward tip of the needle cannula to the dermis layer of the patient's skin.